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Textbook Of Vascular Medicine

Author : Rhian M. Touyz
ISBN : 9783030164812
Genre : Medical
File Size : 54.99 MB
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This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.
Category: Medical

Endothelium And Cardiovascular Diseases

Author : Protasio Lemos Da Luz
ISBN : 9780128125519
Genre : Medical
File Size : 26.27 MB
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Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes
Category: Medical

Vascular Biology Protocols

Author : Nair Sreejayan
ISBN : 9781588295743
Genre : Science
File Size : 59.43 MB
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Over the past decades, the pathogenesis, diagnosis, treatment and prevention of cardiovascular diseases have been benefited significantly from intensive research activities. In order to provide a comprehensive “manual” in a field that has become as broad and deep as cardiovascular medicine, this volume of “Methods in Molecular Medicine” covers a wide spectrum of in vivo and in vitro techniques encompassing biochemical, pharmacological and molecular biology disciplines which are currently used to assess vascular disease progression. Each chapter included in this volume focuses on a specific vascular biology technique and describes various applications as well as caveats of these techniques. The protocols included here are described in detail, allowing beginners with little experience in the field of vascular biology to embark on new research projects.
Category: Science

Heme Oxygenase In Biology And Medicine

Author : Nader G. Abraham
ISBN : 9781461507413
Genre : Medical
File Size : 62.28 MB
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Heme oxygenase is rapidly taking its place as the centerpiece of multiple inter acting metabolic systems. Only 25 years ago heme oxygenase and its metabolic prod ucts appeared to be merely a simple metabolic system-one substrate, heme; one enzyme, heme oxygenase; and one set of products, iron to be recycled, and bilirubin and carbon monoxide to be disposed. From a group of about 25 people in 1974, as judged by attendance at various Gordon conferences, heme oxygenase has, in the year 2000, attracted working scientists-and clinicians I might add-by the hundreds and has produced referenced publications by the thousands. It is well-deserved attention. Heme oxygenase system is now similar to the metabolic networks surrounding glucose in those complex maps of glycolytic and non-glycolytic metabolic pathways, which we had to memorize as students. The relevance of heme oxygenase to regulatory biology was recognized many years ago, but the work conducted over the past five years has created a new wave of emphasis focusing on genetic manipulation to alter heme oxygenase gene expression, the regulatory actions of heme oxygenase products including carbon monoxide, and the significance of changes in the heme oxygenase system. The physiological and pathological relevance of heme oxygenase in the brain, heart, liver, bone marrow, organ transplant, lung and kidney, opens many areas of investigation in various dis ciplines. Advances in the pharmacology of bilirubin and its ability as an antioxidant have provided a new avenue in clinical research.
Category: Medical

Vascular Engineering

Author : Kazuo Tanishita
ISBN : 9784431548010
Genre : Medical
File Size : 70.68 MB
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This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and explains how the impact of related disease conditions — atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction — has generated a focus on developing expertise to both maintain and treat the vascular system. As a comprehensive book in this expanding area, Vascular Engineering serves as a valuable resource for clinicians as well as academics and professionals working in biophysics, biomedical engineering, and nano and microrheology. Graduate students in these subject areas will also find this volume insightful.
Category: Medical

Textbook Of Cardiovascular Medicine

Author : Eric J. Topol
ISBN : 0781770122
Genre : Medical
File Size : 68.10 MB
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The Topol Solution gives you a complete print and multimedia package consisting of Textbook of Cardiovascular Medicine, Third Edition, a DVD, and access to a wealth of online resources. Updated throughout by renowned international authorities, Dr. Topol's best-selling text provides a comprehensive, contemporary view of every area of cardiovascular medicine--preventive cardiology; clinical cardiology; cardiovascular imaging; electrophysiology and pacing; invasive cardiology and surgical techniques; heart failure and transplantation; molecular cardiology; and vascular biology and medicine. The bound-in DVD contains the full text, plus heart sounds, an image/chart/table bank, and videos of procedures--catheterization, CT/MRI, echocardiography, electrophysiology and pacing, intravascular ultrasonography, nuclear cardiology, and surgery. The Topol Solution Website includes the fully searchable text, heart sounds, and an image/chart/table bank downloadable to PowerPoint--plus questions and answers from The Cleveland Clinic Cardiology Board Review; a PDA download of cardiology drug facts; quarterly articles from Critical Pathways in Cardiology, and links to other cardiology Websites.FEATURES: - Thoroughly updated Third Edition of best-selling Textbook of Cardiovascular Medicine, plus DVD and instant access to a wealth of online resources- THE TEXT: - Renowned international contributors- A comprehensive, contemporary view of every area of cardiovascular medicine-preventive cardiology; clinical cardiology; cardiovascular imaging; electrophysiology and pacing; invasive cardiology and surgical techniques; heart failure and transplantation; molecular cardiology; and vascular biology and medicine- Focus on clinical material, particularly the application of clinical research to practice- Each chapter includes comments on current controversies and pioneering insights into future developments- THE BOUND-IN DVD: - Full content of book- Heart sounds-a
Category: Medical

Issues In Physiology Cell Biology And Molecular Medicine 2011 Edition

Author :
ISBN : 9781464965463
Genre : Medical
File Size : 83.74 MB
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Issues in Physiology, Cell Biology, and Molecular Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Physiology, Cell Biology, and Molecular Medicine. The editors have built Issues in Physiology, Cell Biology, and Molecular Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Physiology, Cell Biology, and Molecular Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Physiology, Cell Biology, and Molecular Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at
Category: Medical

A Strategy For Research In Space Biology And Medicine In The New Century

Author : National Research Council
ISBN : 9780309060479
Genre : Science
File Size : 87.29 MB
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Construction of the international space station, scheduled to start in late 1998, ushers in a new era for laboratory sciences in space. This is especially true for space life sciences, which include not only the use of low gravity as an experimental parameter to study fundamental biological processes but also the study of the serious physiological changes that occur in astronauts as they remain in space for increasingly longer missions. This book addresses both of these aspects and provides a comprehensive review of ground-based and space research in eleven disciplines, ranging from bone physiology to plant biology. It also offers detailed, prioritized recommendations for research during the next decade, which are expected to have a considerable impact on the direction of NASA's research program. The volume is also a valuable reference tool for space and life scientists.
Category: Science

Adaptation Biology And Medicine

Author : J. Moravec
ISBN : 0849324270
Genre : Medical
File Size : 27.10 MB
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Taking a science-based look at an emerging area of medicine, Adaptive Biology and Medicine: New Frontiers, Volume 3 discusses the biology of adaptation at the molecular, cellular, and system levels in response to a variety of stressful conditions. Leading international experts present a total of 37 chapters that cover a common continuum of adaptations. For easy reading, the information has been grouped under the sub-headings: Cardiovasular Adaptation, Adaptations to Changes in Altitude and Microgravity, and Environmental Stresses. Examples of cross adaptations are included where repeated exposure to one stimulus may have applications in the treatment and prophylaxis of different diseases. Understanding disease and the mechanisms involved can help us fight disease. When you look at illness through the lens of adaptive biology you can sometimes see medical problems in a new and thought-provoking light. Offering promise for therapeutic strategies in both experimental and clinical pathology, Adaptive Biology and Medicine: New Frontiers explores a new way of thinking about physiological adaptations and their link to disease development.
Category: Medical