Translational Biomedical Informatics

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Translational Biomedical Informatics

Author : Bairong Shen
ISBN : 9789811015038
Genre : Science
File Size : 85.1 MB
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This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.
Category: Science

Biomedical Informatics In Translational Research

Author : Hai Hu
ISBN : 9781596930391
Genre : Computers
File Size : 68.55 MB
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This trailblazing resource on biomedical informatics provides medical researchers with innovative techniques for integrating and federating data from clinical and molecular studies. This volume helps researchers manage data, expedite their efforts, and make the most of targeted basic research.
Category: Computers

Translational Informatics

Author : Philip R.O. Payne
ISBN : 9781447146469
Genre : Medical
File Size : 36.11 MB
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Integrative and translational methodologies and frameworks have transformed modern biomedical research and the delivery of clinical care. This shift has been manifested in a number of ways, including the rapid growth and increasing availability of high-throughput bio-molecular instrumentation and analysis platforms, innovative clinical research programs intended to accelerate knowledge translation, and initial efforts to deliver personalized healthcare informed by the genomic profiles of patients. A common theme of reports and publications concerned with such transformative changes in the biomedical and healthcare domains is concerned with the challenges and opportunities related to the collection, management, integration, analysis, and dissemination of large-scale, heterogeneous biomedical data sets. In particular, the absence of well-established and adopted theoretical and practical frameworks intended to address such needs is a major impediment to the realization of translational and knowledge-driven healthcare, in which the best possible scientific evidence is used to inform the care of every patient. In this vacuum, the development of integrative clinical or translational research paradigms is significantly limited by the propagation of both data and expertise silos. This book details for the first time the current state of this extremely potent area of healthcare innovation and policy and defines the interaction between clinical/translational science and biomedical informatics.​
Category: Medical

Biomedical Informatics Information Systems In Medicine And Health

Author : Cole Webb
ISBN : 1632428792
Genre :
File Size : 68.29 MB
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Biomedical informatics is a field of information engineering that has applications in healthcare, particularly in the management and use of healthcare information. It is an interdisciplinary study that involves the design, adoption, development and IT-based innovations in healthcare services planning, delivery and management. Some of the tools of biomedical informatics are information and communication systems, computers, clinical guidelines, etc. It has applications in the areas of clinical medicine, pharmacy, nursing, public health, occupational therapy, biomedical research and physical therapy, among others. Some of the sub-fields of biomedical informatics are pathology informatics, imaging informatics, community health informatics, consumer health informatics, etc. Translational bioinformatics is an emerging field that integrates bio-statistics, molecular bioinformatics, clinical informatics and statistical genetics. It strives to identify the linkages between biological and clinical information, and enable better approaches to the study and treatment of diseases. This book explores all the important aspects of biomedical informatics in the present day scenario. The various studies that are constantly contributing towards advancing technologies and evolution of this field are examined in detail. The readers would gain knowledge that would broaden their perspective about the use of information systems in medicine and health.
Category:

Translational Informatics In Smart Healthcare

Author : Bairong Shen
ISBN : 9789811057175
Genre : Science
File Size : 35.62 MB
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This book is about the transformation of the biomedical information to smart healthcare, the chapters are designed to discuss the health associated factors such as genetics, lifestyle, nutrition and environmental factors. The interactions of these factors and the informatics for the analyses of their effects on health are also covered. The era of aging is approaching and the P4 (predictive, preventive, personalized and participatory) medicine paradigm is becoming practical and reality. According to the Kondratiev's long wave theory, IT (information technology) and health will be the next technological revolution for the new economic cycle. This book is written for biomedical informatics scientists, clinicians, health practitioners and researchers, etc.
Category: Science

Translational Bioinformatics In Healthcare And Medicine

Author :
ISBN : 9780323898904
Genre : Business & Economics
File Size : 22.21 MB
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Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice. Covers recent advancements in translational bioinformatics and its healthcare applications Discusses integrative and multidisciplinary approaches to U-healthcare systems development and management Bridges the gap among various knowledge domains in the field, integrating both technological and clinical knowledge into practical content
Category: Business & Economics

Translational Bioinformatics And Systems Biology Methods For Personalized Medicine

Author : Qing Yan
ISBN : 9780128043882
Genre : Computers
File Size : 33.3 MB
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Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine. Introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine Presents a problem-solving oriented methodology to deal with practical problems in various applications Covers both basic scientific and clinical applications in order to enhance the collaboration between researchers and clinicians Brings integrative and multidisciplinary approaches to bridge the gaps among various knowledge domains in the field
Category: Computers

Translational Bioinformatics Applications In Healthcare

Author : Khalid Raza
ISBN : 0367705702
Genre :
File Size : 58.2 MB
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Translational bioinformatics (TBI) involves development of storage, analytics and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview and concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare including IoT potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT-images, viroinformatics and viral diseases, COVID-19 related research. Covers recent technologies such as Blockchain, IoT, Big data analytics, in bioinformatics Presents the role of translational bioinformatic methods in the fields of Viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and its applications in better healthcare Explores medical image analysis with focus on CT-image and novel coronavirus disease detection Aimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics.
Category:

Quantified

Author : Dawn Nafus
ISBN : 9780262034173
Genre : Computers
File Size : 81.9 MB
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What is at stake socially, culturally, politically, and economically when we routinely use technology to gather information about our bodies and environments?
Category: Computers

Provenance And Annotation Of Data And Process

Author : Deborah L. McGuinness
ISBN : 9783642178184
Genre : Business & Economics
File Size : 68.3 MB
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The 7 revised full papers, 11 revised medium-length papers, 6 revised short, and 7 demo papers presented together with 10 poster/abstract papers describing late-breaking work were carefully reviewed and selected from numerous submissions. Provenance has been recognized to be important in a wide range of areas including databases, workflows, knowledge representation and reasoning, and digital libraries. Thus, many disciplines have proposed a wide range of provenance models, techniques, and infrastructure for encoding and using provenance. The papers investigate many facets of data provenance, process documentation, data derivation, and data annotation.
Category: Business & Economics

Pediatric Biomedical Informatics

Author : John J. Hutton
ISBN : 9789811011047
Genre : Medical
File Size : 40.67 MB
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The book describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research. The focus is on the authors’ recent practical experiences in establishing an informatics infrastructure in a large research-intensive children’s hospital. This book is intended for translational researchers and informaticians in pediatrics, but can also serve as a guide to all institutions facing the challenges of developing and strengthening informatics support for biomedical research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children.
Category: Medical

Global Healthgrid

Author : Tony Solomonides
ISBN : 9781586038748
Genre : Medical
File Size : 80.3 MB
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HealthGrid 2008 is the sixth conference in this series of open forums for the integration of grid technologies and its applications in the biomedical, medical and biological domains to pave the path to an international research area in healthgrids. The main objective of the HealthGrid conference and the HealthGrid Association is the exchange and discussion of ideas, technologies, solutions and requirements that interest the grid and the life-sciences communities to foster the integration of grids into health. Subjects in this publication reflect the diversity of mature practice: Advancing Virtual Communities, offering a glimpse of the kind of communities that are brought together by means of collaboration grids; Public Health Informatics, exploring the diffusion of grid concepts and technologies in health informatics; Translational Bioinformatics, the contact point between medicine, healthcare and genomics; and Knowledge Management and Decision Support, one direction that is confidently expected to grow as the synergy of grids and 'evidence-based practice' in healthcare is exploited.
Category: Medical

Issues In Biomedical Engineering Research And Application 2011 Edition

Author :
ISBN : 9781464964558
Genre : Technology & Engineering
File Size : 62.95 MB
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Issues in Biomedical Engineering Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biomedical Engineering Research and Application. The editors have built Issues in Biomedical Engineering Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biomedical Engineering Research and Application in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biomedical Engineering Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Category: Technology & Engineering

Applied Computational Genomics

Author : Yin Yao Shugart
ISBN : 9789400755581
Genre : Medical
File Size : 65.65 MB
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"Applied Computational Genomics" focuses on an in-depth review of statistical development and application in the area of human genomics including candidate gene mapping, linkage analysis, population-based, genome-wide association, exon sequencing and whole genome sequencing analysis. The authors are extremely experienced in the area of statistical genomics and will give a detailed introduction of the evolution in the field and critical evaluations of the advantages and disadvantages of the statistical models proposed. They will also share their views on a future shift toward translational biology. The book will be of value to human geneticists, medical doctors, health educators, policy makers, and graduate students majoring in biology, biostatistics, and bioinformatics. Dr. Yin Yao Shugart is investigator in the Intramural Research Program at the National Institute of Mental Health, Bethesda, Maryland USA. ​
Category: Medical

Translational Medicine What Why And How

Author : Barbara Alving
ISBN : 9783318022841
Genre : Science
File Size : 54.67 MB
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This book is the first to provide an aerial view, as well as detailed information, on 'how' activities in translational medicine are under development in countries such as the USA, China, the UK, and Taiwan. Institutions in each country are training investigators to work as sophisticated interdisciplinary teams. Investigators from 11 US academic health centers explain how they are incentivizing collaborations through pilot project programs, forming partnerships with business schools to promote efficient management of basic and clinical research, creating ethical, high- value public-private (industry) partnerships, improving efficiency with utilization of informatics, and engaging the community in research. The essential role of evaluation is explained in a clear and concise manner. The readers will also learn about the role of private funding in Taiwan and the vision of the government in China in developing multiple translational research centers. The UK is developing methodical approaches to patient needs across their lifespans; ongoing innovation is encouraged through incubator programs. With the emphasis on open innovation and sharing, the concepts and practice of translational medicine are spreading rapidly on an international scale.
Category: Science

Bioinformatics For Diagnosis Prognosis And Treatment Of Complex Diseases

Author : Bairong Shen
ISBN : 9789400779754
Genre : Science
File Size : 47.98 MB
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The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction. With the coming of personal genomics era, the biomedical data will be accumulated fast and then it will become reality for the personalized and accurate diagnosis, prognosis and treatment of complex diseases. The book covers both state of the art of bioinformatics methodologies and the examples for the identification of simple or network biomarkers. In addition, bioinformatics software tools and scripts are provided to the practical application in the study of complex diseases. The present state, the future challenges and perspectives were discussed. The book is written for biologists, biomedical informatics scientists and clinicians, etc. Dr. Bairong Shen is Professor and Director of Center for Systems Biology, Soochow University; he is also Director of Taicang Center for Translational Bioinformatics.
Category: Science

Advances In Biotechnology Research And Application 2011 Edition

Author :
ISBN : 9781464921049
Genre : Medical
File Size : 55.22 MB
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Advances in Biotechnology Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biotechnology. The editors have built Advances in Biotechnology Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biotechnology Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Category: Medical

Artificial Intelligence In Medicine

Author : Riccardo Bellazzi
ISBN : 9783540735984
Genre : Medical
File Size : 55.46 MB
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This book constitutes the refereed proceedings of the 11th Conference on Artificial Intelligence in Medicine in Europe, AIME 2007, held in Amsterdam, The Netherlands in July 2007. The 28 revised full papers and 38 revised short papers presented were carefully reviewed and selected from 137 submissions. The papers are organized in topical sections on agent-based systems, temporal data mining, machine learning and knowledge discovery, text mining, natural language processing and generation, ontologies, decision support systems, applications of AI-based image processing techniques, protocols and guidelines, as well as workflow systems.
Category: Medical

Bioinformatics And Biomedical Engineering

Author : Francisco Ortuño
ISBN : 9783319164809
Genre : Computers
File Size : 20.6 MB
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The two volume set LNCS 9043 and 9044 constitutes the refereed proceedings of the Third International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2015, held in Granada, Spain, in April 2015. The 135 papers presented were carefully reviewed and selected from 268 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases, biomedical engineering, biomedical image analysis, biomedical signal analysis, computational genomics, computational proteomics, computational systems for modelling biological processes, e Health, next generation sequencing and sequence analysis, quantitative and systems pharmacology, Hidden Markov Model (HMM) for biological sequence modeling, advances in computational intelligence for bioinformatics and biomedicine, tools for next generation sequencing data analysis, dynamics networks in system medicine, interdisciplinary puzzles of measurements in biological systems, biological networks, high performance computing in bioinformatics, computational biology and computational chemistry, advances in drug discovery and ambient intelligence for bio emotional computing.
Category: Computers

Biomedical Informatics

Author : Edward H. Shortliffe
ISBN : 3030587207
Genre : Medical
File Size : 45.54 MB
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This 5th edition of this essential textbook continues to meet the growing demand of practitioners, researchers, educators, and students for a comprehensive introduction to key topics in biomedical informatics and the underlying scientific issues that sit at the intersection of biomedical science, patient care, public health and information technology (IT). Emphasizing the conceptual basis of the field rather than technical details, it provides the tools for study required for readers to comprehend, assess, and utilize biomedical informatics and health IT. It focuses on practical examples, a guide to additional literature, chapter summaries and a comprehensive glossary with concise definitions of recurring terms for self-study or classroom use. Biomedical Informatics: Computer Applications in Health Care and Biomedicine reflects the remarkable changes in both computing and health care that continue to occur and the exploding interest in the role that IT must play in care coordination and the melding of genomics with innovations in clinical practice and treatment. New and heavily revised chapters have been introduced on human-computer interaction, mHealth, personal health informatics and precision medicine, while the structure of the other chapters has undergone extensive revisions to reflect the developments in the area. The organization and philosophy remain unchanged, focusing on the science of information and knowledge management, and the role of computers and communications in modern biomedical research, health and health care.
Category: Medical