Tissue Engineering And Regeneration In Dentistry

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Tissue Engineering And Regeneration In Dentistry

Author : Rachel J. Waddington
ISBN : 9781118741078
Genre : Medical
File Size : 52.94 MB
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Tissue Engineering and Regeneration in Dentistry: Current Strategies presents a thorough update on the current advances, methods and understanding in tissue engineering in dentistry. It offers invaluable tools, case studies, and methodologies for undertaking research, including important biological and practical considerations to facilitate successful migration of research from the bench to the clinic. Offers detailed coverage of the basic underlying principles and scientific evidence, and includes protocols to highlight practical applications Written by an internationally renowned team of expert contributors A must-have read for researchers and specialist clinicians in tissue engineering, oral biology, dental materials science, periodontology and oral surgery
Category: Medical

Stem Cell Biology And Tissue Engineering In Dental Sciences

Author : Ajaykumar Vishwakarma
ISBN : 9780123977786
Genre : Medical
File Size : 53.77 MB
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Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine Print book is available and black and white, and the ebook is in full color
Category: Medical

Applications Of Biomedical Engineering In Dentistry

Author : Lobat Tayebi
ISBN : 9783030215835
Genre : Technology & Engineering
File Size : 88.63 MB
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This book offers readers a valuable overview of recent advances in biomedical engineering, as applied to the modern dentistry. It begins by studying the biomaterials in dentistry, and materials used intraoperatively during oral and maxillofacial surgery procedures. Next, it considers the subjects in which biomedical engineers can be influential, such as 3-dimensional (3D) imaging, laser and photobiomodulation, surface modification of dental implants, and bioreactors. Hard and soft tissue engineerings in dentistry are discussed, and some specific and essential methods such as 3D-printing are elaborated. Presenting particular clinical functions of regenerative dentistry and tissue engineering in treatment of oral and maxillofacial soft tissues is the subject of a separate chapter. Challenges in the rehabilitation handling of large and localized oral and maxillofacial defects is a severe issue in dentistry, which are considered to understand how bioengineers help with treatment methods in this regard. Recent advances in nanodentistry is discussed followed by a chapter on the applications of stem cell-encapsulated hydrogel in dentistry.Periodontal regeneration is a challenging issue in dentistry, and thus, is going to be considered separately to understand the efforts and achievements of tissue engineers in this matter. Oral mucosa grafting is a practical approach in engineering and treatment of tissues in ophthalmology, which is the subject of another chapter. Microfluidic approaches became more popular in biomedical engineering during the last decade; hence, one chapter focuses on the advanced topic of microfluidics technologies using oral factors as saliva-based studies. Injectable gels in endodontics is a new theme in dentistry that bioengineering skills can advance its development, specifically by producing clinically safe and effective gels with regeneration and antibacterial properties. Engineered products often need to be tested in vivo before being clinical in dentistry; thus, one chapter is dedicated to reviewing applicable animal models in dental research. The last chapter covers the progress on the whole tooth bioengineering as a valuable and ultimate goal of many dental researchers. Offers readers an interdisciplinary approach that relates biomedical engineering and restorative dentistry Discusses recent technological achievements in engineering with applications in dentistry Provides useful tool to dental companies for future product planning, specifically to biomedical engineers engaged in dental research
Category: Technology & Engineering

Regenerative Endodontics An Issue Of Dental Clinics E Book

Author : Sami M.A. Chogle
ISBN : 9781455747535
Genre : Medical
File Size : 67.13 MB
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Regenerative endodontics is the generation and replacement of diseased, damaged or absent pulp. This issue of Dental Clinics of North America provides a clinical view of regenerative endodontics and its aims, methods and techniques.
Category: Medical

Regenerative Dentistry

Author : Mona Marei
ISBN : 9781608452149
Genre : Technology & Engineering
File Size : 34.96 MB
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Dental caries, periodontitis, tooth loss, and bone resorption are considered prevalent health problems that have direct affect on the quality of life. While, advances in stem cell biology and biotechnology have sparked hope for devastating maladies, such as diabetes, cardiovascular diseases, etc., it also provides a strategy of regenerative therapy for dental tissues. From the prospective of tissue engineering, it is of utmost importance to understand and emulate the complex cell interactions that make up a tissue or organ. Unlike other tissues in the body, dental tissues are unique in their development, function, and even in their maintenance throughout life. The harmonized stimulations of biology and mechanical regulators to promote cellular activities have matured our understanding of the value of regenerative therapy of dental tissue versus the reparative treatment. In this book, we review the current knowledge available to regenerate alveolar bone, periodontal structure, and pulp/dentin complex. The book provides researchers with detailed information about development and functional characteristics of the dental unit with detailed protocols covering a comprehensive range of various approaches to engineer dental tissues: to use isolated cells or cell substitutes as cellular replacement, to use acellular biomaterials capable of inducing tissue regeneration, and/or to use a combination of cells, biomaterial and growth factors. We are well aware, with the concept changes in the field toward in-vitro biomimetics of in-vivo tissue development. The theoretical frame work integrating these concepts of developmental biology and developmental engineering is yet to be emphasized and implemented. Until this happens, we consider this book of regenerative dentistry as a call for scientists to achieve, researchers to innovate, practitioners to apply, and students to learn the art and science of regenerative therapy in dentistry. Table of Contents: Introduction to Regenerative Dentistry / Tissue Engineering Alveolar Bone / Tissue Engineering of the Periodontal Tissues / Dynamics for Pulp-Dentin Tissue Engineering in Operative Dentistry
Category: Technology & Engineering

Craig S Restorative Dental Materials E Book

Author : Ronald L. Sakaguchi
ISBN : 9780323082518
Genre : Medical
File Size : 54.47 MB
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Master the use of dental materials in the clinic and dental laboratory and stay current with this ever-changing field with Craig's Restorative Dental Materials, 13th Edition. From fundamental concepts to advanced skills, this comprehensive text details everything you need to know to understand the scientific basis for selecting dental materials when designing and fabricating restorations. This practical, clinically relevant approach to the selection and use of dental materials challenges you to retain and apply your knowledge to realistic clinical scenarios, giving you an authoritative advantage in dental practice. Problems and Solutions at the end of each chapter test your ability to apply chapter concepts to solve common clinical challenges. Mind Maps on the companion Evolve website condense essential chapter content into single-page overviews ideal for quick reference, study outlines, or comprehensive reviews. Comprehensive coverage reflects fundamental concepts and the latest practical knowledge all in one authoritative source. Appendix of useful resource materials provides quick, convenient access to Weights and Measurements, Conversion Tables, and Comparative Table of Troy, Avoirdupois, and Metric Weights. Content updates and links on Evolve keep you current with the latest developments in the field. NEW! Full-color design and illustrations clarify clinical detail for greater understanding. NEW! Reorganized content emphasizes scientific evidence and is organized by usage in a clinical setting to help you study more efficiently. NEW! Digital Imaging and Processing for Restorations chapter equips you with essential understanding of current imaging practices. NEW! Major revisions reflect the latest advances in the use of enamel, dental, biofilms, mechanical testing, ceramics, polymers, and composites.
Category: Medical

Handbook Of Intelligent Scaffolds For Tissue Engineering And Regenerative Medicine

Author : Gilson Khang
ISBN : 9781315341026
Genre : Medical
File Size : 40.85 MB
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Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.
Category: Medical

Biomaterials For Oral And Dental Tissue Engineering

Author : Lobat Tayebi
ISBN : 9780081009673
Genre : Technology & Engineering
File Size : 76.43 MB
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Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers in academia and industry. The first set of chapters reviews a wide range of biomaterial classes for oral tissue engineering. Further topics include material characterization, modification, biocompatibility and biotoxicity. Part Two reviews strategies for biomaterial scaffold design, while chapters in parts three and four review soft and hard tissues. Connects materials science with restorative dentistry Focuses on the unique field of intraoral tissues Highlights long-term biocompatibility and toxicity of biomaterials for engineered oral tissues
Category: Technology & Engineering

Advances In Craniofacial And Dental Materials Through Nanotechnology And Tissue Engineering

Author : Giovanna Orsini
ISBN : 9782889458585
Genre :
File Size : 61.41 MB
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Dental and craniofacial treatments are actually based on advances in biomaterials, tissue engineering and nanotechnology sciences. These developments brought considerable improvements on biomaterials commonly used in dental clinics. However, there is still a medical need for innovative techniques and materials for a controllable and efficient regeneration/repair of damaged craniofacial tissues and teeth. The novel biomaterials, imaging techniques, diagnostic and technological tools may offer thrilling perspectives for alternative treatments in dentistry.
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Dental Stem Cells Regenerative Potential

Author : Barbara Zavan
ISBN : 9783319332994
Genre : Science
File Size : 28.41 MB
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This book focuses on the basic aspects of dental stem cells (DSCs) as well as their clinical applications in tissue engineering and regenerative medicine. It opens with a discussion of classification, protocols, and properties of DSCs and proceeds to explore DSCs within the contexts of cryopreservation; epigenetics; pulp, periodontal, tooth, bone, and corneal stroma regeneration; neuronal properties, mesenchymal stem cells and biomaterials; and as sources of hepatocytes for liver disease treatment. The fifteen expertly authored chapters comprehensively examine possible applications of DSCs and provide invaluable insights into mechanisms of growth and differentiation. Dental Stem Cells: Regenerative Potential draws from a wealth of international perspectives and is an essential addition to the developing literature on dental stem cells. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is indispensable for biomedical researchers interested in bioengineering, dentistry, tissue engineering, regenerative medicine, cell biology and oncology.
Category: Science

Cohen S Pathways Of The Pulp Expert Consult E Book

Author : Louis H. Berman
ISBN : 9780323079075
Genre : Medical
File Size : 74.66 MB
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The definitive endodontics reference, Cohen’s Pathways of the Pulp is known for its comprehensive coverage of leading-edge information, materials, and techniques. It examines all aspects of endodontic care, from preparing the clinician and patient for endodontic treatment to the role the endodontist can play in the treatment of traumatic injuries and to the procedures used in the treatment of pediatric and older patients. Not only does Hargreaves and Cohen’s 10th edition add five chapters on hot new topics, it also includes online access! As an Expert Consult title, Cohen’s Pathways of the Pulp lets you search the entire contents of the book on your computer, and includes five online chapters not available in the printed text, plus videos, a searchable image collection, and more. For evidence-based endodontics research and treatment, this is your one-stop resource!
Category: Medical

Stem Cells And Cancer Stem Cells Volume 5

Author : M.A. Hayat
ISBN : 9789400729001
Genre : Medical
File Size : 74.78 MB
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It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor. It is emphasized that a unique feature of cancer stem cells is that, although conventional chemotherapy kills most cells in a tumor, cancer stem cells remain intact. Vast applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, human mesenchymal stem cells, cancer stem cells, arterial stem cells, neural stem cells, cardiac stem cells, dental stem cells, limbal stem cells, and hematopoietic stem cells. Because human embryonic stem cells possess the potential to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential in this volume. These cells are used in tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. It is pointed out that the formation of embryoid bodies, which are three-dimensional aggregates of embryonic cells, is the initial step in the differentiation of these cells. Therapeutic implications of signalling pathways in cancer stem cells are pointed out. Targeting self-renewal pathways in cancer stem cells are also included. Application of mesenchymal stem cells for treating ischemic brain injury is explained. Neural stem cells proliferation into the surrounding area of the traumatic brain injury is explained.
Category: Medical

Current Advances In Oral And Craniofacial Tissue Engineering

Author : Vincenzo Guarino
ISBN : 9780429750830
Genre : Medical
File Size : 86.44 MB
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Oral tissue engineering involves the study of current approaches for in vitro regeneration of soft and hard tissues located into the oral cavity. In this context, recent approaches involves the use of innovative biomaterials to replace the lost or damaged human oral tissues. Recent discoveries in materials science and nanotechnology are drastically changing the traditional approach to dentistry by the design of innovative devices able more efficiently supporting the natural regeneration process. The objective of this book is to highlight current progress in tissue engineering for various dental hard/soft tissues including enamel, dentin, pulp, alveolar bone, periodontium, gum and oral mucosa, by emphasizing the role of materials and their specific applications.
Category: Medical

Tissue Engineering Use Of Growth Factors In Bone Regeneration

Author : Carmen Mortellaro
ISBN : OCLC:1154305758
Genre : Technology
File Size : 41.77 MB
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Tissue healing is a complex process involving a cascade of cellular and molecular events that are mostly shared by the different tissues of the body. Interestingly, the tissue repair process initiates immediately after a traumatic injury and is mediated and controlled by a wide range of cytokines, proteins, and growth factors released from platelets upon activation. Consequently, many growth factors have been considered as therapeutic molecules for the repair or regeneration of a wide range of tissues. Although their role has been only partially elucidated, the potential benefit of most growth factors has been demonstrated. In the last few years, the development of platelet-rich preparations has revolutionized the field of regenerative medicine, due to the repair capacities of the platelet-released growth factors that stimulate and accelerate both soft and hard tissue healing and regeneration. Today, autologous platelet concentrates (APCs) are used in a wide range of disciplines such as dentistry, oral surgery, orthopedics, sport medicine, dermatology, and plastic and reconstructive surgery. The purpose of this chapter is to describe the current evidence regarding the benefits of using autologous platelet concentrates in various oral surgery procedures, using a systematic review approach.
Category: Technology

Comprehensive Biomaterials

Author : Paul Ducheyne
ISBN : 9780080552941
Genre : Technology & Engineering
File Size : 24.23 MB
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Comprehensive Biomaterials brings together the myriad facets of biomaterials into one, major series of six edited volumes that would cover the field of biomaterials in a major, extensive fashion: Volume 1: Metallic, Ceramic and Polymeric Biomaterials Volume 2: Biologically Inspired and Biomolecular Materials Volume 3: Methods of Analysis Volume 4: Biocompatibility, Surface Engineering, and Delivery Of Drugs, Genes and Other Molecules Volume 5: Tissue and Organ Engineering Volume 6: Biomaterials and Clinical Use Experts from around the world in hundreds of related biomaterials areas have contributed to this publication, resulting in a continuum of rich information appropriate for many audiences. The work addresses the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, and strategic insights for those entering and operational in diverse biomaterials applications, research and development, regulatory management, and commercial aspects. From the outset, the goal was to review materials in the context of medical devices and tissue properties, biocompatibility and surface analysis, tissue engineering and controlled release. It was also the intent both, to focus on material properties from the perspectives of therapeutic and diagnostic use, and to address questions relevant to state-of-the-art research endeavors. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance as well as future prospects Presents appropriate analytical methods and testing procedures in addition to potential device applications Provides strategic insights for those working on diverse application areas such as R&D, regulatory management, and commercial development
Category: Technology & Engineering

3d Bioprinting And Nanotechnology In Tissue Engineering And Regenerative Medicine

Author : Lijie Grace Zhang
ISBN : 9780128006641
Genre : Technology & Engineering
File Size : 76.27 MB
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3D Bioprinting and Nanotechnology in Tissue Engineering provides an in depth introduction to these two technologies and their industrial applications. Stem cells in tissue regeneration are covered, along with nanobiomaterials. Commercialization, legal and regulatory considerations are also discussed in order to help you translate nanotechnology and 3D printing-based products to the marketplace and the clinic. Dr. Zhang’s and Dr. Fishers’ team of expert contributors have pooled their expertise in order to provide a summary of the suitability, sustainability and limitations of each technique for each specific application. The increasing availability and decreasing costs of nanotechnologies and 3D printing technologies are driving their use to meet medical needs, and this book provides an overview of these technologies and their integration. It shows how nanotechnology can increase the clinical efficiency of prosthesis or artificial tissues made by bioprinting or biofabrication. Students and professionals will receive a balanced assessment of relevant technology with theoretical foundation, while still learning about the newest printing techniques. Includes clinical applications, regulatory hurdles, and risk-benefit analysis of each technology. This book will assist you in selecting the best materials and identifying the right parameters for printing, plus incorporate cells and biologically active agents into a printed structure Learn the advantages of integrating 3D printing and nanotechnology in order to improve the safety of your nano-scale materials for biomedical applications
Category: Technology & Engineering

Tissue Engineering

Author : John P. Fisher
ISBN : 9781439874035
Genre : Medical
File Size : 45.72 MB
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Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the fi
Category: Medical

Introduction To Nanomedicine And Nanobioengineering

Author : Paras N. Prasad
ISBN : 9781118351079
Genre : Science
File Size : 73.57 MB
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This book is an introduction to the emerging field of nanomedicine and its applications to health care. It describes the many multidisciplinary challenges facing nanomedicine and discusses the required collaboration between chemists, physicists, engineers and clinicians. The book introduces the reader to nanomedicine's vast potential to improve and extend human life through the application of nanomaterials in diagnosis and treatment of disease.
Category: Science

Treatment Of Periodontal Disease An Issue Of Dental Clinics E Book

Author : Frank A. Scannapieco
ISBN : 9781455700233
Genre : Medical
File Size : 28.32 MB
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Articles include: Current Rationale for Treatment of Periodontitis, Effects of Periodontal Treatment on Systemic Health, Non-Surgical Mechanical Treatment Strategies, Use of Lasers to Treat Periodontal Diseases, Regeneration of Periodontal Tissues: Bone Grafts, Implants and Periodontal Patient, Regeneration of Periodontal Tissues: Growth Factors and Bone Morphogenetic Protein, Treatment of Gingival Recession, Non-surgical Chemotherapeutic Treatment Strategies, Regeneration of Periodontal Tissues: Guided, Future Approaches in Periodontal Therapy: Gene Therapy, RNA Interference and Stem Cells, and Restorative Trends for the Periodontal Patient.
Category: Medical