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Author : Vladimir P. Torchilin
ISBN : 0849383080
Genre : Medical
File Size : 33.16 MB
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This is the first time detailed and updated information on the targeted delivery of imaging agents has been collected into a single handbook. This comprehensive volume presents the scientific background together with the latest experimental and clinical data in this fast-growing area. The Handbook of Targeted Delivery of Imaging Agents meets the requirements of the broadest audience including researchers, practitioners, and students. The basic principles of targeted delivery of imaging are presented and discussed together with various imaging agents and different imaging modalities such as gamma-imaging, MR-imaging, and CT, PET, and SPECT imaging. The book consists of eight parts and 39 chapters covering all aspects of targeted drug delivery-from the imaging theory and chemistry of imaging agents to their experimental and clinical use for targeted visualization of cancer, including ovarian, prostate, colorectal, and thyroid cancer, cardiovascular (atherosclerosis, myocardial infarction, and thromboses) and neurological diseases, infection, and inflammation sites. A special section discusses the targeted delivery of imaging agents into lymph nodes, which are often sites of metasteses during different malignant diseases. Monoclonal antibody-based targeted imaging agents are considered together with new approaches involving the use of labeled micelles, liposomes, and polymer-coated particles. The book describes the possible application of designer antibodies for the delivery of diagnostic agents, including the preparation, properties, labeling, and experimental use of multifunctional antibodies. The alternative improvement of antibody-directed targeting describes the application of avidin-biotin system for the delivery of imaging agents. Long circulating blood pool imaging agents are considered as a special group of organ-specific pharmaceuticals. The latest trends in the synthesis of immunoscintigraphic, MR, and CT agents are presented. This Handbook of Targeted Delivery of Imaging Agents is a must-have reference for all those who need to stay abreast of the latest developments in this hot field.
Author : Len Fulton
ISBN : 0913218383
Genre : Language Arts & Disciplines
File Size : 37.20 MB
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The biggest revision in ten years of the Bible of the business (Wall Street Journal). This essential reference for writers, librarians, students of modern literature, and readers worldwide was started in the 1960s during the initial phase of the small-press revolution. It is safe to say that, in its forty-first edition, the directory is a publishing legend. It includes information on over 5,000 presses and journals from around the world, listing addresses, manuscript requirements, payment rates, and recent publications. Subject and regional indexes are also provided.
Author : Len Fulton
ISBN : 0913218006
Genre : Language Arts & Disciplines
File Size : 65.58 MB
Format : PDF, Kindle
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The biggest revision in ten years of "the Bible of the business" (Wall Street Journal). This essential reference for writers, librarians, students of modern literature, and readers worldwide was started in the 1960s during the initial phase of the small-press revolution. It is safe to say that, in its forty-first edition, the directory is a publishing legend. It includes information on over 5,000 presses and journals from around the world, listing addresses, manuscript requirements, payment rates, and recent publications. Subject and regional indexes are also provided.
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ISBN : UOM:39015023731568
Genre : Arts
File Size : 81.11 MB
Format : PDF, Kindle
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A multidisciplinary index covering the journal literature of the arts and humanities. It fully covers 1,144 of the world's leading arts and humanities journals, and it indexes individually selected, relevant items from over 6,800 major science and social science journals.