The Mysterious Epigenome

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The Mysterious Epigenome

Author : Thomas Woodward
ISBN : 9780825488825
Genre : Religion
File Size : 77.43 MB
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In this creative and inventive treatment, authors Thomas E. Woodward and James P. Gills take readers on an exploration of the human epigenome. Acting as tour guides leading visitors through a 3-D model of a human cell, Woodward and Gills bring to life the human molecular makeup. Readers (as visitors) will get up close and personal with the minute details of human molecular structure, including E. coli, flagellum, a DNA helix, an RNA molecule, and more. By seeing it with their own eyes, readers will gain a better understanding of their genetic systems and a better appreciation for the Creator who put this all into place.
Category: Religion

Why Can T I Get Better Solving The Mystery Of Lyme And Chronic Disease

Author : Richard Horowitz
ISBN : 9781250038487
Genre : Health & Fitness
File Size : 30.29 MB
Format : PDF
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From one of the country's foremost doctors comes a ground-breaking book about diagnosing, treating and healing Lyme, and peeling away the layers that lead to chronic disease. You may not know that you have Lyme. It can mimic every disease process including Chronic Fatigue Syndrome, Fibromyalgia, autoimmune conditions like MS, psychiatric conditions like depression and anxiety, and cause significant memory and concentration problems, mimicking early dementia. It is called the "Great Imitator," and inaccurate testing-combined with a fierce, ongoing debate that questions chronic infection-makes it difficult for sufferers to find effective care. When Dr. Richard Horowitz moved to the Hudson Valley over two decades ago to start his own medical practice, he had no idea that he was jumping into a hotbed of Lyme disease. He would soon realize that many of the chronic disease diagnoses people were receiving were also the result of Lyme-and he would discover how once-treatable infections, in the absence of timely intervention, could cause disabling conditions. In a field where the number of cases is growing exponentially around the world and answers remain elusive, Dr. Horowitz has treated over 12,000 patients and made extraordinary progress. His plan represents a crucial paradigm shift, without which the suffering will continue. In this book, Dr. Horowitz: - Breaks new ground with a 16 Point Differential Diagnostic Map, the basis for his revolutionary Lyme treatment plan, and an overarching approach to treating all chronic illness. - Introduces MSIDS, or Multiple Systemic Infectious Disease Syndrome, a new lens on chronic illness that may prove to be an important missing link. - Covers in detail Lyme's leading symptoms and co-infections, including immune dysfunction, sleep disorders, chronic pain and neurodegenerative disorders - providing a unique functional and integrative health care model, based on the most up-to-date scientific research, for physicians and health care providers to effectively treat Lyme and other chronic illnesses. Cutting through the frustration, misinformation and endless questions, Dr. Horowitz's enlightening story of medical discovery, science and politics is an all-in-one source for patients of chronic illness to identify their own symptoms and work with their doctors for the best possible treatment outcome.
Category: Health & Fitness

A Reasonable Accommodation

Author : David K. Shortess
ISBN : 9781449786359
Genre : Nature
File Size : 50.63 MB
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Have you ever wondered... Why do people have to suffer? Did the Garden of Eden really exist? Is there evidence of design in the universe? Why is there so much sin and evil in the world? Was there really a worldwide flood in Noah’s day? Do non-physical, supernatural entities actually exist? Were Adam and Eve a unique, divinely created couple? Who was Cain’s wife, and who did he fear would kill him? What is the age of the earth, thousands or billions of years? Was the tree of the knowledge of good and evil really a tree? Can evolution account for the diversity of life on earth today?
Category: Nature

The Developing Genome

Author : David S. Moore
ISBN : 9780190613761
Genre : Psychology
File Size : 75.60 MB
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Why do we grow up to look, act, and feel as we do? Through most of the twentieth century, scientists and laypeople answered this question by referring to two factors alone: our experiences and our genes. But recent discoveries about how genes work have revealed a new way to understand the developmental origins of our characteristics. These discoveries have emerged from the new science of behavioral epigenetics--and just as the whole world has now heard of DNA, "epigenetics" will be a household word in the near future. Behavioral epigenetics is important because it explains how our experiences get under our skin and influence the activity of our genes. Because of breakthroughs in this field, we now know that the genes we're born with don't determine if we'll end up easily stressed, likely to fall ill with cancer, or possessed of a powerful intellect. Instead, what matters is what our genes do. And because research in behavioral epigenetics has shown that our experiences influence how our genes function, this work has changed how scientists think about nature, nurture, and human development. Diets, environmental toxins, parenting styles, and other environmental factors all influence genetic activity through epigenetic mechanisms; this discovery has the potential to alter how doctors treat diseases, and to change how mental health professionals treat conditions from schizophrenia to post-traumatic stress disorder. These advances could also force a reworking of the theory of evolution that dominated twentieth-century biology, and even change how we think about human nature itself. In spite of the importance of this research, behavioral epigenetics is still relatively unknown to non-biologists. The Developing Genome is an introduction to this exciting new discipline; it will allow readers without a background in biology to learn about this work and its revolutionary implications.
Category: Psychology

Epigenetic Epidemiology

Author : Karin B. Michels
ISBN : 9789400724945
Genre : Medical
File Size : 82.34 MB
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The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!
Category: Medical

Epigenetics In Retinoblastoma

Author : Sophia Stahl
ISBN : 9783656347057
Genre : Medical
File Size : 66.49 MB
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Essay from the year 2012 in the subject Medicine - Ophthalmology, grade: 1,3, University of Heidelberg, language: English, abstract: Today's DNA sequencing technologies are becoming more and more impressive. That it is not only important to focus on mutations in the sequence of DNA, however, but also on differences that occur on the level above the genes, the epigenetic modifications of the DNA, has been found out by the researchers of Michael Dyer's group. The quickly developing childhood cancer retinoblastoma is directly related to the inactivation of the tumor suppressor gene RB1. With RB1 having different roles relevant for understanding this cancer, the process leading to advancing retinoblastoma after its inactivation is not yet understood. After analysis of the genome and the epigenome of different retinoblastomas, the genome was detected as relatively stable. A newly proposed part of the chain of events leading to the outbreak of this severe cancer is as follows. Biallelic loss of RB1 leads to the deregulation of epigenetic mechanisms and thereby also of cancer pathways. This is followed by cells acquiring the characteristics of cancer cells. With the experiments conducted by Dyer et al., the proto-oncogene SYK (spleen tyrosine kinase) was found to be upregulated in retinoblastoma and also necessary for the survival of the tumor cells. With SYK inhibited, increasing apoptosis of the cancer cells could be observed. The conclusion seems likely that SYK promises to be a new target for treating retinoblastoma patients and a broader approach in research, including not only genomic data, but also epigenetic analyses, is necessary for better understanding of cancer in the future.
Category: Medical

Cancer Autism And Their Epigenetic Roots

Author : K. John Morrow, Jr.
ISBN : 9781476615639
Genre : Health & Fitness
File Size : 41.65 MB
Format : PDF
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This book considers the branch of heredity known as “epigenetics” and its implications for a variety of diseases in humans and animals. After background information on the growth in understanding genetics and the mechanisms of the epigenetic control of gene expression, the book moves into its main focus: the gathering body of evidence connecting genetics to a range of significant illnesses, including cancer, autism, Alzheimer’s disease, diabetes and others. Areas of uncertainty are stressed as well as the scientific debate concerning the role of environmental factors. The final chapters discuss the implications for society. Extensive notes provide additional details and personal anecdotes.
Category: Health & Fitness

God Of Wonders

Author : David A. Steen
ISBN : 9780828025119
Genre : Religion
File Size : 67.61 MB
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Explore the wonders of God's creation with biologist David A. Steen, and discover the intricacies of things we usually take for granted: taste, gravity, skin, bacteria, trees, DNA, stars, cellular reproduction, and many more. Are you ready to experience an overwhelming sense of awe? God's creative genius is simply breathtaking.
Category: Religion

Nutrition Concepts And Controversies Myplate Update

Author : Frances Sizer
ISBN : 9781285226002
Genre : Medical
File Size : 64.86 MB
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Why not have it ALL for your Introductory Nutrition course? With Sizer/Whitney's NUTRITION: CONCEPTS AND CONTROVERSIES, MYPLATE UPDATE, 12e you can! A trusted author team with unparalleled research and excellent writing A modern textbook thoroughly updated with 2010 Dietary Guidelines, MyPlate, and Healthy People 2020. A superior program integrated with market-leading Diet Analysis software to meet all teaching and learning objectives. Updated with the 2010 Dietary Guidelines, MyPlate, and Healthy People 2020, NUTRITON: CONCEPTS AND CONTROVERSIES, MYPLATE UPDATE, continues to focus on core nutrition principles and their personal applications while offering outstanding coverage of the biological foundations of nutrition without assuming previous knowledge. The authors' lively, approachable writing style gives students just the right amount of detail--striking the perfect balance between scientific research, core concepts, and applications that provide a meaningful context for students. Drawing readers into the study of nutrition, the text dispels students' existing misconceptions, and empowers them to make better nutrition choices and enact real, lasting behavior change. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Category: Medical

Time

Author :
ISBN : NWU:35556039813092
Genre : Periodicals
File Size : 35.59 MB
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Category: Periodicals

Genius Foods

Author : Max Lugavere
ISBN : 9780062562890
Genre : Health & Fitness
File Size : 60.28 MB
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New York Times Bestseller Discover the critical link between your brain and the food you eat and change the way your brain ages, in this cutting-edge, practical guide to eliminating brain fog, optimizing brain health, and achieving peak mental performance from media personality and leading voice in health Max Lugavere. After his mother was diagnosed with a mysterious form of dementia, Max Lugavere put his successful media career on hold to learn everything he could about brain health and performance. For the better half of a decade, he consumed the most up-to-date scientific research, talked to dozens of leading scientists and clinicians around the world, and visited the country’s best neurology departments—all in the hopes of understanding his mother’s condition. Now, in Genius Foods, Lugavere presents a comprehensive guide to brain optimization. He uncovers the stunning link between our dietary and lifestyle choices and our brain functions, revealing how the foods you eat directly affect your ability to focus, learn, remember, create, analyze new ideas, and maintain a balanced mood. Weaving together pioneering research on dementia prevention, cognitive optimization, and nutritional psychiatry, Lugavere distills groundbreaking science into actionable lifestyle changes. He shares invaluable insights into how to improve your brain power, including the nutrients that can boost your memory and improve mental clarity (and where to find them); the foods and tactics that can energize and rejuvenate your brain, no matter your age; a brain-boosting fat-loss method so powerful it has been called “biochemical liposuction”; and the foods that can improve your happiness, both now and for the long term. With Genius Foods, Lugavere offers a cutting-edge yet practical road map to eliminating brain fog and optimizing the brain’s health and performance today—and decades into the future.
Category: Health & Fitness

The Scientific American Book Of Love Sex And The Brain

Author : Judith Horstman
ISBN : 9781118109533
Genre : Psychology
File Size : 82.68 MB
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Who do we love? Who loves us? And why? Is love really a mystery, or can neuroscience offer some answers to these age-old questions? In her third enthralling book about the brain, Judith Horstman takes us on a lively tour of our most important sex and love organ and the whole smorgasbord of our many kinds of love-from the bonding of parent and child to the passion of erotic love, the affectionate love of companionship, the role of animals in our lives, and the love of God. Drawing on the latest neuroscience, she explores why and how we are born to love-how we're hardwired to crave the companionship of others, and how very badly things can go without love. Among the findings: parental love makes our brain bigger, sex and orgasm make it healthier, social isolation makes it miserable-and although the craving for romantic love can be described as an addiction, friendship may actually be the most important loving relationship of your life. Based on recent studies and articles culled from the prestigious Scientific American and Scientific American Mind magazines, The Scientific American Book of Love, Sex, and the Brain offers a fascinating look at how the brain controls our loving relationships, most intimate moments, and our deep and basic need for connection.
Category: Psychology

Cardiovascular Genetics And Genomics In Clinical Practice

Author : Donna K. Arnett, PhD
ISBN : 9781617051784
Genre : Medical
File Size : 87.73 MB
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Weighted Numerical Score: 100 - 5 Stars! This is a systematic guide to cardiovascular genetics and genomics from basic concepts to clinical application. It organizes a large volume of information from an active area of research, which holds promise for future discovery. --Doody's Reviews Cardiovascular Genetics and Genomics in Clinical Practice presents clinical cases to illuminate basic concepts of cardiovascular genetics and genomics as practitioners encounter them in day-to-day practice. The unique use of real-world case discussions facilitates the memorization and understanding of basic principles, which can be more readily applied to actual cases. Cardiovascular Genetics and Genomics in Clinical Practice features a step-by-step learning process that begins with an easy-to-understand "primer" of basic scientific concepts regarding cardiovascular genetics and genomics followed by state-of-the-art research and applications for treatment of cardiovascular disorders. Expert clinicians and researchers describe illustrative cases for each topic along with detailed discussions of current scientific understanding and its application in current disease management and treatment. Summaries, key teaching points, and illustrations are highlighted to facilitate quick recall and review. The book will be useful for cardiovascular clinicians in training, board preparation, or as a review for those already in clinical practice. Cardiovascular Genetics and Genomics in Clinical Practice features: Clinical case scenarios to illuminate the basic concepts of cardiovascular genetics and genomics as they are used in daily practice Explanation of fundamental concepts as a foundation for more in-depth understanding Detailed discussions of current scientific knowledge and clinical management The expertise of renowned clinician-scientists in the field Real practical insight for practice
Category: Medical

Bioinformatics For Geneticists

Author : Michael R. Barnes
ISBN : 9780470026199
Genre : Computers
File Size : 63.77 MB
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Bioinformatics for geneticists describes the key bioinformatics and genetic analysis processes that are needed to identify human genetic determinants. Including SNP functional analysis and statistical genetics.
Category: Computers

Science

Author : John Michels
ISBN : UIUC:30112037736946
Genre : Science
File Size : 27.36 MB
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Category: Science