Systems Biology A Very Short Introduction

Download Systems Biology A Very Short Introduction ebook PDF or Read Online books in PDF, EPUB, and Mobi Format. Click Download or Read Online button to Systems Biology A Very Short Introduction book pdf for free now.

Systems Biology A Very Short Introduction

Author : Eberhard O. Voit
ISBN : 9780192563453
Genre : Science
File Size : 61.81 MB
Format : PDF, ePub
Download : 979
Read : 504

Systems biology came about as growing numbers of engineers and scientists from other fields created algorithms which supported the analysis of biological data in incredible quantities. Whereas biologists of the past had been forced to study one item or aspect at a time, due to technical and biological limitations, it suddenly became possible to study biological phenomena within their natural contexts. This interdisciplinary field offers a holistic approach to interpreting these processes, and has been responsible for some of the most important developments in the science of human health and environmental sustainability. This Very Short Introduction outlines the exciting processes and possibilities in the new field of systems biology. Eberhard O. Voit describes how it enabled us to learn how intricately the expression of every gene is controlled, how signaling systems keep organisms running smoothly, and how complicated even the simplest cells are. He explores what this field is about, why it is needed, and how it will affect our understanding of life, particularly in the areas of personalized medicine, drug development, food and energy production, and sustainable stewardship of our environments. Throughout he considers how new tools are being provided from the fields of mathematics, computer science, engineering, physics, and chemistry to grasp the complexity of the countless interacting processes in cells which would overwhelm the cognitive and analytical capabilities of the human mind. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Science

Earth System Science

Author : Tim Lenton
ISBN : 9780198718871
Genre :
File Size : 77.99 MB
Format : PDF, Kindle
Download : 299
Read : 391

When humanity first glimpsed planet Earth from space, the unity of the system that supports humankind entered the popular consciousness. The concept of the Earth's atmosphere, biosphere, oceans, soil, and rocks operating as a closely interacting system has rapidly gained ground in science. This new field, involving geographers, geologists, biologists, oceanographers, and atmospheric physicists, is known as Earth System Science. In this Very Short Introduction, Tim Lenton considers how a world in which humans could evolve was created; how, as a species, we are now reshaping that world; and what a sustainable future for humanity within the Earth System might look like. Drawing on elements of geology, biology, chemistry, physics, and mathematics, Lenton asks whether Earth System Science can help guide us onto a sustainable course before we alter the Earth system to the point where we destroy ourselves and our current civilisation. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category:

Synthetic Biology A Very Short Introduction

Author : Jamie A. Davies
ISBN : 9780192525277
Genre : Science
File Size : 63.17 MB
Format : PDF, Docs
Download : 922
Read : 1201

Synthetic biology is one of the 21st century's fastest growing fields of research, as important for technology as for basic science. Building on traditional genetic engineering, which was restricted to changing one or two genes, synthetic biology uses multi-gene modules and pathways to make very significant changes to what cells can do. Synthetic biologists aim to have an impact in fields as diverse as drug manufacture, biofuel production, tackling pollution, and medical diagnostics. Further ahead, synthetic biology may even make possible the long-standing goal of creating new life from non-living starting materials. This Very Short Introduction provides a concise explanation of what synthetic biology is, and how it is beginning to affect many fields of technology. Jamie Davies also discusses the considerable controversies surrounding synthetic biology, from questions over the assumption that engineering concepts can be applied to living systems easily, to scepticism over the claims for commercial promise, fears that the dangers of engineering life are worse than its benefits, and concerns over whether humans should be designing living systems at all. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Science

Marine Biology A Very Short Introduction

Author : Philip V. Mladenov
ISBN : 9780199695058
Genre : Science
File Size : 43.58 MB
Format : PDF
Download : 267
Read : 674

In this Very Short Introduction, Philip Mladenov provides a fascinating overview of marine biology. Including a tour of marine life and marine processes that ranges from the polar oceans to tropical coral reefs, he outlines the principles of marine biology whilst demonstrating the fundamental impact humans have on the oceans and their ecology.
Category: Science

Human Anatomy

Author : Leslie Klenerman
ISBN : 9780198707370
Genre : Medical
File Size : 86.16 MB
Format : PDF, ePub
Download : 166
Read : 749

An understanding of the structure and function of the human body is vital for anyone studying the medical and health sciences. In this book, Leslie Klenerman provides a clear and accessible overview of the main systems of the human anatomy, illustrated with a number of clear explanatory diagrams.
Category: Medical

Computer Science A Very Short Introduction

Author : Subrata Dasgupta
ISBN : 9780198733461
Genre : Computers
File Size : 59.57 MB
Format : PDF, Docs
Download : 131
Read : 287

Over the past sixty years, the spectacular growth of the technologies associated with the computer is visible for all to see and experience. Yet, the science underpinning this technology is less visible and little understood outside the professional computer science community. As a scientific discipline, computer science stands alongside the likes of molecular biology and cognitive science as one of the most significant new sciences of the post Second World War era. In this Very Short Introduction, Subrata Dasgupta sheds light on these lesser known areas and considers the conceptual basis of computer science. Discussing algorithms, programming, and sequential and parallel processing, he considers emerging modern ideas such as biological computing and cognitive modelling, challenging the idea of computer science as a science of the artificial. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Computers

Lakes

Author : Warwick F. Vincent
ISBN : 9780198766735
Genre : Science
File Size : 24.1 MB
Format : PDF, Docs
Download : 945
Read : 512

From the mysterious depths of Lake Vostok, Antarctica, to tropical floodplain lakes, inland seas, hydro-reservoirs and the variety of waterbodies in our local environment, lakes encompass a huge diversity of shapes, sizes, depths, colours, and even salinities. Often very large and very deep,they sustain important and unique ecosystems which can be hotspots of biodiversity, and are used by humans as sources of drinking water and food, in particular, fish. What is the origin of differences among lakes, and how does that affect the life within them? What are the seasons of a lake, and howdo human actions alter lake ecosystems locally, and at a global scale? In this Very Short Introductions, Warwick Vincent outlines the essential features of lake environments and their biology, offering an up-to-date view of lake ecosystems. Vincent traces the origins of lake science (limnology) from the seminal work of Francois Forel on Lake Geneva at the edge of theSwiss Alps, to modern approaches such as environmental sensors, satellite observations, stable isotope analysis, and DNA-based technologies which are used to probe the microbial life support systems that lead from sunlight to fish. Drawing on varied case studies he considers the intimaterelationship between humans and lakes, the value of lakes as indicators of environmental change, the impact of pollution,and our urgent need to improve the protection and management of these vitally important living resources via an integrated understanding of their ecology. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.
Category: Science

Complexity

Author : John H. Holland
ISBN : 9780199662548
Genre : History
File Size : 24.87 MB
Format : PDF, ePub, Docs
Download : 285
Read : 557

In this Very Short Introduction, John Holland presents an introduction to the science of complexity. Using examples from biology and economics, he shows how complexity science models the behaviour of complex systems.
Category: History

Veterinary Science

Author : James Yeates
ISBN : 9780198790969
Genre : Medical
File Size : 37.42 MB
Format : PDF
Download : 729
Read : 884

Every year billions of animals, from housecats to racehorses to pythons, are treated by veterinarians. The use of veterinary science to treat the health of animals has a long history; for the past five centuries it has developed as our understanding of animals' fundamental biology, pathology, and pharmacology has grown. Rapid global changes expected in the twenty-first century will require the profession to respond proactively, embracing new challenges and opportunities. James Yeates, Chief Veterinary Officer of the RSPCA, introduces the field of veterinary science, covering the history of its scientific and clinical aspects from early practices to recent challenges such as the outbreak of BSE and antibiotic resistance, and considering the differences between human medicine and veterinary medicine. Analyzing the key roles played by diagnosis, treatment, and prevention with regard to the health of farm animals and pets, he relates this to wider aspects concerning public health, such as zoonoses (diseases that jump from animals to humans). Yeates also covers recent "One Health" approaches involving the health of both humans and animals, seen as synergistic, and discusses the challenges for the future of veterinary medicine, including the ethical dilemmas in balancing the interests of owners and animals when they do not coincide. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Medical

Developmental Biology A Very Short Introduction

Author : Lewis Wolpert
ISBN : 9780199601196
Genre : Science
File Size : 60.24 MB
Format : PDF, Docs
Download : 160
Read : 387

"A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.
Category: Science

Symmetry A Very Short Introduction

Author : Ian Stewart
ISBN : 9780191652745
Genre : Mathematics
File Size : 40.25 MB
Format : PDF
Download : 888
Read : 1234

In the 1800s mathematicians introduced a formal theory of symmetry: group theory. Now a branch of abstract algebra, this subject first arose in the theory of equations. Symmetry is an immensely important concept in mathematics and throughout the sciences, and its applications range across the entire subject. Symmetry governs the structure of crystals, innumerable types of pattern formation, how systems change their state as parameters vary; and fundamental physics is governed by symmetries in the laws of nature. It is highly visual, with applications that include animal markings, locomotion, evolutionary biology, elastic buckling, waves, the shape of the Earth, and the form of galaxies. In this Very Short Introduction, Ian Stewart demonstrates its deep implications, and shows how it plays a major role in the current search to unify relativity and quantum theory. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Mathematics

The Immune System A Very Short Introduction

Author : Paul Klenerman
ISBN : 9780191068485
Genre : Medical
File Size : 82.30 MB
Format : PDF, Kindle
Download : 449
Read : 932

The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine. In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behaviour, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called "innate" immune responses, which react very fast to infection, and "adaptive" immune responses, which have huge diversity and a capacity to recognise and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the "Immune system v2.o" — how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Medical

The Scientific Revolution A Very Short Introduction

Author : Lawrence Principe
ISBN : 9780199567416
Genre : Science
File Size : 48.62 MB
Format : PDF, ePub, Docs
Download : 423
Read : 434

Lawrence M. Principe takes a fresh approach to the story of the scientific revolution, emphasising the historical context of the society and its world view at the time. From astronomy to alchemy and medicine to geology, he tells this fascinating story from the perspective of the historical characters involved.
Category: Science

The Cell A Very Short Introduction

Author : Terence Allen
ISBN : 9780191620263
Genre : Science
File Size : 23.82 MB
Format : PDF, ePub
Download : 347
Read : 738

All living things on Earth are composed of cells. A cell is the simplest unit of a self-contained living organism, and the vast majority of life on Earth consists of single-celled microbes, mostly bacteria. These consist of a simple 'prokaryotic' cell, with no nucleus. The bodies of more complex plants and animals consist of billions of 'eukaryotic' cells, of varying kinds, adapted to fill different roles - red blood cells, muscle cells, branched neurons. Each cell is an astonishingly complex chemical factory, the activities of which we have only begun to unravel in the past fifty years or so through modern techniques of microscopy, biochemistry, and molecular biology. In this Very Short Introduction, Terence Allen and Graham Cowling describe the nature of cells - their basic structure, their varying forms, their division, their differentiation from initially highly flexible stem cells, their signalling, and programmed death. Cells are the basic constituent of life, and understanding cells and how they work is central to all biology and medicine. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Science

Foundations Of Systems Biology

Author : Masao Nagasaki
ISBN : 1848820232
Genre : Science
File Size : 39.58 MB
Format : PDF, Docs
Download : 628
Read : 1234

Today, as hundreds of genomes have been sequenced and thousands of proteins and more than ten thousand metabolites have been identi?ed, navigating safely through this wealth of information without getting completely lost has become crucial for research in, and teaching of, molecular biology. Consequently, a considerable number of tools have been developed and put on the market in the last two decades that describe the multitude of potential/putative interactions between genes, proteins, metabolites, and other biologically relevant compounds in terms of metabolic, genetic, signaling, and other networks, their aim being to support all sorts of explorations through bio-data bases currently called Systems Biology. As a result, navigating safely through this wealth of information-processing tools has become equally crucial for successful work in molecular biology. To help perform such navigation tasks successfully, this book starts by providing an extremely useful overview of existing tools for ?nding (or designing) and inv- tigating metabolic, genetic, signaling, and other network databases, addressing also user-relevant practical questions like • Is the database viewable through a web browser? • Is there a licensing fee? • What is the data type (metabolic, gene regulatory, signaling, etc. )? • Is the database developed/maintained by a curator or a computer? • Is there any software for editing pathways? • Is it possible to simulate the pathway? It then goes on to introduce a speci?c such tool, that is, the fabulous “Cell - lustrator 3. 0” tool developed by the authors.
Category: Science

Systems Biology And Regulatory Genomics

Author : Eleazar Eskin
ISBN : 9783540482932
Genre : Science
File Size : 39.13 MB
Format : PDF
Download : 548
Read : 1257

This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2005 satellite events: the First Annual Workshop on Systems Biology, RSB 2005 and the Second Annual Workshop on Regulatory Genomics, RRG 2005, held in San Diego, CA, USA in December 2005. It contains 21 revised full papers that address a broad variety of topics in systems biology and regulatory genomics.
Category: Science

Evolution A Very Short Introduction

Author : Brian Charlesworth
ISBN : 9780191577666
Genre : Science
File Size : 52.89 MB
Format : PDF, Kindle
Download : 780
Read : 788

Less than 450 years ago, all European scholars believed that the earth was the centre of a universe that was at most a few million miles in extent, and that the planets, sun, and stars all rotated around this centre. Less than 250 years ago, they believed that the universe was created essentially in its present state about 6000 years ago. Less than 150 years ago, the special creation by God of living species was still dominant. The relentless application of the scientific method of inference from experiment and observation, without reference to religious, or governmental authority has completely transformed our view of our origins and relation to the universe, in less than 500 years. Few would dispute that this programme has been spectacularly successful, particularly in the twentieth century. This book is about the crucial role of evolutionary biology in transforming our view of human origins and relation to the universe, and the impact of this idea on traditional philosophy and religion. The purpose of this book is to introduce the general reader to some of the most important basic findings, concepts, and procedures of evolutionary biology, as it has developed since the first publications of Darwin and Wallace on the subject, over 140 years ago. Evolution provides a unifying set of principals for the whole of biology; it also illuminates the relation of human beings to the universe and each other. In addition, many aspects of evolution have practical importance; for instance, the rapid evolution of resistance by bacteria to antibiotics and of HIV to antiviral drugs are pressing medical problems. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Science

Advances In Computational Biology

Author : Luis F. Castillo
ISBN : 9783319015682
Genre : Computers
File Size : 70.86 MB
Format : PDF, ePub, Docs
Download : 365
Read : 738

This volume compiles accepted contributions for the 2nd Edition of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous review process in which 54 papers were accepted for publication from 119 submitted contributions. Bioinformatics and Computational Biology are areas of knowledge that have emerged due to advances that have taken place in the Biological Sciences and its integration with Information Sciences. The expansion of projects involving the study of genomes has led the way in the production of vast amounts of sequence data which needs to be organized, analyzed and stored to understand phenomena associated with living organisms related to their evolution, behavior in different ecosystems, and the development of applications that can be derived from this analysis.
Category: Computers

Biogeography A Very Short Introduction

Author : Mark V. Lomolino
ISBN : 9780198850069
Genre : Science
File Size : 80.48 MB
Format : PDF
Download : 942
Read : 832

Biogeography is the study of geographic variation in all characteristics of life - ranging from genetic, morphological and behavioural variation among regional populations of a species, to geographic trends in diversity of entire communities across our planet's sufrace. From the ancient hunters and gatherers to the earliest naturalists, Charles Darwin, Alfred Russel Wallace, and scientists today, the search for patterns in life has provided insights that proved invaluable for understanding the natural world. And many, if not most, of the compelling kaleidoscope of patterns in biological diversity make little sense unless placed in an explicit geographic context. The Very Short Introduction explains the historical development of the field of biogeography, its fundamental tenets, principles and tools, and the invaluable insights it provides for understanding the diversity of life in the natural world. As Mark Lomolino shows, key questions such as where species occur, how they vary from place to place, where their ancestors occurred, and how they spread across the globe, are essential for us to develop effective strategies for conserving the great menagerie of life across our planet. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Science

Forensic Science A Very Short Introduction

Author : Jim Fraser
ISBN : 9780191609664
Genre : Science
File Size : 41.70 MB
Format : PDF, Mobi
Download : 635
Read : 1266

Forensic science is a subject of wide fascination. What happens at a crime scene? How does DNA profiling work? How can it help solve crimes that happened 20 years ago? In forensic science, a criminal case can often hinge on a piece of evidence such as a hair, a blood trace, half a footprint, or a tyre mark. High profile cases such as the Stephen Lawrence enquiry and the Madeleine McCann case have attracted enormous media attention and enhanced this interest in recent years. However, the public understanding of forensic science is poor, and largely based on TV shows such as CSI: Crime Scene Investigation, which exploit high-tech imagery for dramatic effect. Forensic science is a complex activity at the interface of science and law. However, it also deals with real life issues and its results are interpreted within unique situations. Complex scientific findings must be considered carefully, dispassionately, and communicated with clarity, simplicity, and precision. In this Very Short Introduction, Jim Fraser introduces the concept of forensic science and explains how it is used in the investigation of crime. He begins at the crime scene itself, explaining the principles and processes of crime scene management. He explores how forensic scientists work; from the reconstruction of events to laboratory examinations. He considers the techniques they use, such as fingerprinting, and goes on to highlight the immense impact DNA profiling has had. Providing examples from forensic science cases in the UK, US, and other countries, he considers the techniques and challenges faced around the world. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Science