STAPHYLOCOCCUS GENETICS AND PHYSIOLOGY

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Staphylococcus

Author : Greg A. Somerville
ISBN : 1910190497
Genre : Science
File Size : 54.57 MB
Format : PDF
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In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research. This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.
Category: Science

Staphylococcus

Author : Greg A. Somerville
ISBN : 9781910190500
Genre : Medical
File Size : 47.89 MB
Format : PDF
Download : 900
Read : 1042

In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research. This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.
Category: Medical

Staphylococci In Human Disease

Author : Kent B. Crossley
ISBN : 1444308475
Genre : Medical
File Size : 25.29 MB
Format : PDF, Kindle
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Staphylococci remain the most important cause of hospital-acquiredinfections in the U.S. and MRSA has become the most common cause ofskin and soft tissue infection in many parts of the world. There is now a much greater understanding of the physiology andevolution of the staphylococci and this new edition reflects therapid advancements in knowledge about this pathogen and provides acomprehensive review from both clinical and basic scienceperspectives. The first section addresses the basic biology of thestaphylococci, their molecular genetics, host defenses and hostevasion, virulence determinants, mechanisms of antibioticresistance, and laboratory techniques. The second section dealswith epidemiology, and the third section provides an overview ofthe varied clinical manifestations of human staphylococcalinfections. The fourth section covers prevention and treatment ofthese often life-threatening infections. Written by experts from around the globe, this book is essentialreading for all clinicians and basic scientists studying thestaphylococci.
Category: Medical

The Staphylococci And Staphylococcal Pathogenesis

Author : David Heinrichs
ISBN : 9782889190577
Genre :
File Size : 47.57 MB
Format : PDF, Docs
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Members of the genus Staphylococcus play important roles in disease causation in humans and animals. Over the past decade, the completed sequencing of many staphylococcal genomes has contributed to a surge in the number of publications, which have promoted a tremendous advance in our knowledge of these important pathogens. Significant developments include the emergence of new and highly virulent strains of S. aureus, advances in tracking the evolution of human and animal adapted strains, a heightened appreciation of the role of mobile genetic elements in antibiotic resistance and pathogenesis, and important insights into staphylococcal physiology, immune evasion strategies, and cell surface proteins, as well as significant advances in vaccine development and therapeutics. This Research Topic will focus attention on the latest developments in these areas as they pertain to S. aureus and members of the coagulase-negative Staphylococci, and will also strive to identify areas of future development.
Category:

Physiology And Genetics

Author : Timm Anke
ISBN : 3642002862
Genre : Science
File Size : 62.97 MB
Format : PDF, ePub
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In the last decade the discipline of mycology has been substantially changed by new research technologies. In particular DNA-based tools for the investigation of fungal taxonomy, signal transduction and regulation, and biosynthetic potential have accelerated advances in mycological knowledge. This volume presents a selection of exciting issues on basic and applied aspects of fungal physiology and genetics. In 18 chapters renowned experts provide an overview of traditional as well as current and future aspects of potential application of fungi in biotechnology. The contributions can be used by scientists to keep up-to-date on the latest developments in the corresponding research area, and by students to familiarize themselves with the different topics.
Category: Science

Staphylococcus Aureus Infection And Disease

Author : Allen Honeyman
ISBN : 9780306468483
Genre : Medical
File Size : 87.58 MB
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Staphylococcus aureus is now acknowledged as being the most important bacterial pathogen of humans. It usually produces localized disease but can be rapidly invasive, spreading through the tissues, invading bone, and seeding the bloodstream to produce a fulminant picture of septic shock, disseminated intravascular coagulation, and rapid death. Moreover, most strains of staph infections are becoming resistant to most antibiotics, thus posing a significant problem for hospitals and health care facilities. This book, a volume in the Infectious Agents and Pathogenesis series, presents chapters by the major researchers in the field.
Category: Medical

Anatomy And Physiology For Midwives E Book

Author : Jane Coad
ISBN : 9780702045936
Genre : Medical
File Size : 42.99 MB
Format : PDF
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Anatomy & Physiology for Midwives 3rd edition builds on the success of the first two editions with electronic ancillaries, more accessible, woman-centred language and strengthened links with good practice. The book provides a thorough review of anatomy and physiology applicable to midwifery, from first principles through to current research, utilizing case studies for reflection. A comprehensive and well-illustrated textbook that is an essential purchase for all students of midwifery.
Category: Medical

Nutraceutical And Functional Food Processing Technology

Author : Joyce I. Boye
ISBN : 9781118504970
Genre : Technology & Engineering
File Size : 55.65 MB
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For several years, the food industry has been interested inidentifying components in foods which have health benefits to beused in the development of functional food and nutraceuticalproducts. Examples of these ingredients include fibre,phytosterols, peptides, proteins, isoflavones, saponins, phyticacid, probiotics, prebiotics and functional enzymes. Although muchprogress has been made in the identification, extraction andcharacterisation of these ingredients, there remains a need forready and near-market platform technologies for processing theseingredients into marketable value-added functional food andnutraceutical products. This book looks at how these ingredientscan be effectively incorporated into food systems for market, andprovides practical guidelines on how challenges in specific foodsectors (such as health claims and marketing) can be addressedduring processing. Nutraceutical and Functional Food Processing Technologyis a comprehensive overview of current and emerging trends in theformulation and manufacture of nutraceutical and functional foodproducts. It highlights the distinctions between foods falling intothe nutraceutical and functional food categories. Topics includesustainable and environmentally–friendly approaches to theproduction of health foods, guidelines and regulations, and methodsfor assessing safety and quality of nutraceutical and functionalfood products. Specific applications of nutraceuticals in emulsionand salad dressing food products, beverages and soft drinks, bakedgoods, cereals and extruded products, fermented food products arecovered, as are novel food proteins and peptides, and methods forencapsulated nutraceutical ingredients and packaging. The impact ofprocessing on the bioactivity of nutraceutical ingredients,allergen management and the processing of allergen-free foods,health claims and nutraceutical food product commercialization arealso discussed. Nutraceutical and Functional Food Processing Technologyis a comprehensive source of practical approaches that can be usedto innovate in the nutraceutical and health food sectors. Fullyup-to-date and relevant across various food sectors, the book willbenefit both academia and industry personnel working in the healthfood and food processing sectors.
Category: Technology & Engineering