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Side Effects Of Cancer Chemotherapy On The Gastrointestinal Tract

Author : M. Staritz
ISBN : 0792387910
Genre : Medical
File Size : 63.51 MB
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Cancer chemotherapy frequently attacks the gastrointestinal tract. Many of the possible side-effects reduce the patient's quality of life, may limit acceptance of further drug administration, and even life-threatening complications must be considered. This book is the proceedings of the Falk Workshop 'Side-effects of Chemotherapy on the Gastrointestinal Tract: Pathogenesis and Therapy', held in Freiburg, Germany, on October 11, 2002 (Part IV of the Freiburg Gastroenterology Week). Chapters by pathologists, pharmacologists, oncologists and gastroenterologists will improve our understanding of the effects of anticancer agents on the organs of the gastrointestinal tract and help to compensate for chemotherapy-induced adverse effects.
Category: Medical

Side Effects

Author : Michael Palmer
ISBN : 9780307781215
Genre : Fiction
File Size : 28.68 MB
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“Has everything—a terrifying plot . . . breakneck pace . . . vividly drawn characters.”—John Saul Kate Bennet. A bright hospital pathologist with a loving husband and a solid future. Until one day her world turns dark. A strange, puzzling illness has killed two women. Now it endangers Kate's closest friend. Soon it will threaten Kate's marriage. Her sanity. Her life. Kate has uncovered a horrifying secret. Important people will stop at nothing to protect it. It is a terrifying medical discovery. And its roots lie in one of the greatest evils in the history of humankind.
Category: Fiction


Author : Graziano Pinna
ISBN : 1634820762
Genre :
File Size : 81.94 MB
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Fluoxetine, best known by the trade name Prozac®, unlike other psychotropic drugs whose effects were serendipitously stumbled upon, was the first developed for a precise mechanism of action, that is, the ability to selectively inhibit serotonin reuptake, based upon the theory that increasing the availability of serotonin would treat major depression. Once approved by the FDA in 1987, fluoxetine quickly became the most prescribed psychotropic drug worldwide and its success in improving mood disorders has triggered the development of a large number of congener molecules, commonly known as SSRIs after their purported mechanism of action. However, a quarter of a century after its development, the idea that fluoxetine asserts its positive behavioral effect through inhibition of serotonergic reuptake is not firmly established. This book reviews several preclinical and clinical reports suggesting that the pharmacological effects of fluoxetine may be mediated by means other than the regulation of serotonin, including the regulation of gene expression, modifying epigenetic mechanisms as well as modifying microRNAs. One of the most prominent mechanisms for the therapeutic relevance of fluoxetine relates to influencing neuroplasticity by enhancing neurotropic factors, including BDNF signaling and altering adult neurogenesis. The ability of fluoxetine to rapidly increase neurosteroid levels accounts for the fast anxiolytic effects of this drug. Fluoxetine action at sigma-1 receptor or modulating glutamatergic neurotransmission as well as the combination of fluoxetine with other psychotropic drugs is discussed in relation to its therapeutic effects. While fluoxetine was primarily prescribed as an antidepressant, this drug currently represents a treatment of choice for a broad spectrum of psychiatric disorders, including post-traumatic stress disorder and a range of anxiety disorders. This drug even possesses analgesic actions and is a valuable therapy for stroke. This book also highlights emerging evidence on the gender-specific effects of fluoxetine, its potential adverse features, including its addiction liability in combination with psychostimulants, and the impact of perinatal fluoxetine exposure.

Meyler S Side Effects Of Endocrine And Metabolic Drugs

Author : Jeffrey K. Aronson
ISBN : 0080932924
Genre : Medical
File Size : 51.85 MB
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Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician. Endocrine and metabolic diseases are common, includes diseases such as diabetes, thyroid disease, and obesity. Endocrinologists, including diabetes professionals, internal medicine and primary care practitioners, obstetricians and gynecologists, and others will find this book useful when treating endocrine or metabolic diseases. The material is drawn from the 15th edition of the internationally renowned encyclopedia, Meyler’s Side Effects of Drugs, and the latest volumes in the companion series, Side Effects of Drugs Annuals. Drug names have usually been designated by their recommended or proposed International Non-proprietary Names (rINN or pINN); when those are not available, clinical names have been used. In some cases, brand names have been used. This volume is critical for any health professional involved in the administration of endocrine and metabolics mediations. Surpasses the Physician’s Desk Reference © by including clinical case studies and independent expert analysis Complete index of drug names Most complete cross referencing of drug-drug interactions available Extensive references to primary and secondary literature Also includes information on adverse effects in pregnancy The book is divided into eight sections: Corticosteroids and related drugs Prostaglandins Sex hormones and related drugs Iodine and drugs that affect thyroid function Insulin and other hypoglycemic drugs Other hormones and related drugs Lipid-regulated drugs Endocrine and metabolic adverse effects of non-hormonal and non-metabolic drugs
Category: Medical

Psychiatric Side Effects Of Prescription And Over The Counter Medications

Author : Thomas Markham Brown
ISBN : 0880488689
Genre : Medical
File Size : 33.38 MB
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Both prescription and non-prescription medications used in medicine and psychiatry can cause a varietyof problems for those taking them, both in terms of their behavior and their ability to think. The first book to thoroughly examine how to recognize and manage the psychological side-effects of these medicines, this exhaustive work also provides a fingertip source of vital information for everyone from psychiatrists, primary care doctors and other medical subspecialty practitioners to students, residents and general readers. Noted physicians Thomas Markham Brown and Alan Stoudemire cover all of the major medications used in medicine and psychiatry, with full chapters on such topics as: * Antipsychotics* Antidepressants* Lithium* Anticonvulsants* Anesthetic agents* Sedative-Hypnotic and related agents* Antibiotics* Cardiovascular agents* Antineoplastic agents* Gastrointestinal agents* Pulmonary agents* Hematologic agents* Antilipemic agents* Drugs affecting the endocrine system Throughout this information-packed reference, the authors, noted physicians Thomas Markham Brown and Alan Stoudemire, cover all of the major medications used in medicine and psychiatry. They focus on the fundamental ways drugs cause cognitive toxicity and map strategies for clinical management. They also address the consequences of drug interactions and the basic pathophysiology of central nervous system toxicity. With the help of Psychiatric Side Effects of Prescription and Over-the-Counter Medications, readers will be able to quickly identify the ways drugs sometimes negatively affect behavior and ability to reason, and then determine the best practical course for treating those problems. A CD-ROM containing the complete contents of Psychiatric Side Effects of Prescription and Over the Counter Medications is included. Fully searchable, this CD-ROM is compatible on both MACINTOSH and WINDOWS systems.
Category: Medical

Side Effects

Author : Amy Goldman Koss
ISBN : 1429935820
Genre : Young Adult Fiction
File Size : 89.53 MB
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Serious, funny, compelling -- and unique: a novel about a teenager with cancer and doesn't die, from Amy Goldman Koss, acclaimed author of THE GIRLS. As if it isn't bad enough to have cancer, practically every time we pick up a book or hear about a character in a movie who gets sick, we know they'll be dead by the last scene. In reality, kids get all kinds of cancers, go through unspeakable torture and painful treatments, but walk away, fine in the end. Isabelle, not quite 15, is living a normal life of fighting with her younger brother, being disgusted with her parents, and hoping to be noticed by a cute guy. Everything changes in an instant when she is diagnosed with lymphoma-- and even her best friend, Kay, thinks Izzy is going to die. But she doesn't, and her humor—sardonic, sharp, astute -- makes reading this book accessible and actually enjoyable. From the acclaimed author of The Girls and Poison Ivy, Side Effects is about the pain, fear, and unlikely comedy of 15-year-old Izzy's journey, told in her own powerful and authentic voice. It is Izzy's story—screams and all.
Category: Young Adult Fiction

Side Effects Of Drugs Annual

Author : Jeffrey K. Aronson
ISBN : 0080522815
Genre : Medical
File Size : 45.39 MB
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The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then, as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has contributed to the Annuals by selecting critically from each year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is misleading. Provides a critical yearly survey of new data and trends Includes an essay that describes the modern approach to classifying adverse drug reactions Special reviews in this Annual include, among other topics: Antipsychotic drugs and now-onset diabetes mellitus, Treating asthma during pregnancy, and MMR vaccine and autism
Category: Medical

Antipsychotics And Their Side Effects

Author : David M. Gardner
ISBN : 9781139491921
Genre : Medical
File Size : 43.7 MB
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With the remarkable expansion in the use of antipsychotics, concerns about their immediate, intermediate, and long-term adverse effects have intensified. Despite this, studies consistently show that monitoring of patients taking antipsychotics can be inadequate, haphazard, or worse. This book provides a comprehensive review of the adverse effects of this pharmacologically complex therapeutic class, covering all commonly used conventional and atypical agents. In the first section, each chapter provides background information about an adverse effect, reviews the evidence linking the effect to various antipsychotics, and provides specific detection and monitoring recommendations. The second section provides unique monitoring guides for each antipsychotic. The third section provides the clinician with a program to monitor patients over the long-term. By supporting rational treatment decisions and systematic adverse effect monitoring, Antipsychotics and their Side Effects provides the clinician with the necessary information and tools for optimizing the safe and effective long-term use of antipsychotic drugs.
Category: Medical

A Guide To The Extrapyramidal Side Effects Of Antipsychotic Drugs

Author : D. G. Cunningham Owens
ISBN : 1139425919
Genre : Medical
File Size : 48.34 MB
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Antipsychotic drugs have revolutionised the management of major psychiatric disorders and the outcomes of those who suffer from them. They are, however, possessed of a range of adverse effects, amongst the most frequent and distressing of which are those resulting in disturbance of voluntary motor function. Extrapyramidal side effects - or E.P.S. - are still poorly recognised and not infrequently misattributed. Despite a vast research literature, there have been few attempts to bring together both the descriptive clinical elements of these disorders and major research conclusions pertinent to routine practice. This very readable and well illustrated 1999 book seeks to rectify this in the hope of increasing clinicians' awareness of the issues and acknowledgement of their impact. This is a task made more rather than less urgent with the emergence of drugs of lower liability but which may promote subtler abnormality than standard compounds.
Category: Medical