ROLE OF CAPSAICIN IN OXIDATIVE STRESS AND CANCER 3 DIET AND CANCER

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Role Of Capsaicin In Oxidative Stress And Cancer

Author : Sanjay K. Srivastava
ISBN : 9789400763173
Genre : Medical
File Size : 89.55 MB
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This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
Category: Medical

Fruit And Vegetable Phytochemicals

Author : Elhadi M. Yahia
ISBN : 9781119157960
Genre : Technology & Engineering
File Size : 41.10 MB
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Now in two volumes and containing more than seventy chapters, the second edition of Fruit and Vegetable Phytochemicals: Chemistry, Nutritional Value and Stability has been greatly revised and expanded. Written by hundreds of experts from across the world, the chapters cover diverse aspects of chemistry and biological functions, the influence of postharvest technologies, analysis methods and important phytochemicals in more than thirty fruits and vegetables. Providing readers with a comprehensive and cutting-edge description of the metabolism and molecular mechanisms associated with the beneficial effects of phytochemicals for human health, this is the perfect resource not only for students and teachers but also researchers, physicians and the public in general.
Category: Technology & Engineering

Cancer

Author : Victor R. Preedy
ISBN : 9780124055247
Genre : Medical
File Size : 35.22 MB
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Cancer: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide and covers in a single volume the science of oxidative stress in cancer and then the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component of this. Oncologists, cancer researchers, and nutritionists are separated by divergent skills and professional disciplines that need to be bridged in order to advance preventative as well as treatment strategies. While oncologists and cancer researchers may study the underlying pathogenesis of cancer, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of oncology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of cancer. Nutritionists can apply information related to mitochondrial oxidative stress in one disease to diet-related strategies in another unrelated disease Dietitians can prescribe new foods or diets containing anti-oxidants for conditions resistant to conventional pharmacological treatments Dietitians, after learning about the basic biology of oxidative stress, will be able to suggest new treatments to their multidisciplinary teams Nutritionists and dietitians will gain an understanding of cell signaling, and be able to suggest new preventative or therapeutic strategies with anti-oxidant rich foods
Category: Medical

Pharma Nutrition

Author : Gert Folkerts
ISBN : 9783319061511
Genre : Medical
File Size : 38.95 MB
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Natural products and functional/medical foods are now widely acknowledged as having an effect on the microbiome of the intestine, which in turn influences the outcome of certain disease. This book reviews the impact and effects of natural products and functional/medical foods (nutritional programming) on disease management, specifically focusing on diseases related to 1) Inflammation and Immunity, 2) Cancer, COPD and Cachexia, 3) Allergy and 4) Brain Neuro/Immune. Hippocrates said "let medicine be thy food and food be thy medicine". While most of us are familiar with Hippocrates famous words, we admit that in recent times, the disciplines of pharma and nutrition have evolved separately. Today, with the ever growing burden of diseases in modern society, we see a convergence of the two in relation to specific disease prevention and treatment. This re-discovered common ground between the complementary values of pharma and nutrition can be conceptualized in the term pharma-nutrition. Various chapters in the book review the aspects of molecular characteristics of food ingredients towards clinical effectiveness and relevance.
Category: Medical

Nutrition And Cancer From Epidemiology To Biology

Author : Pier Paolo Claudio
ISBN : 9781608054473
Genre : Medical
File Size : 67.85 MB
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Various estimates suggest that between 30-40% of all human cancers are related to dietary patterns. Strong epidemiological evidence from population and twin studies points to dietary constituents that either contribute or protect against the development o
Category: Medical

Herbs And Natural Supplements Inkling

Author : Lesley Braun
ISBN : 9780729579100
Genre : Medical
File Size : 82.39 MB
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A must-have health companion for herbalists, naturopaths, complementary medicine practitioners and students Herbs and Natural Supplements, 3rd Edition: An evidence-based guide presents evidence-based information on the 130 most popular herbs, nutrients and food supplements used across Australia and New Zealand. This exhaustive textbook is organised alphabetically by each herb or nutrient’s common name. Herbs and nutrients are then accompanied by critical information such as daily intake, main actions and indications, adverse reactions, contraindications and precautions, safety in pregnancy and more. This new edition of Herbs and Natural Supplements has been expanded with new chapters on pregnancy and wellness. It also features 10 new monographs for Arginine, Dunaliella, Elde, Goji, Pelargonium, Prebiotics, Red Yeast Rice, Rhodioloa, Shatavari and Taurine. • provides current, evidence-based information on herbal, nutritional and food supplements used in Australia and New Zealand • is user-friendly and easily organised by easy-to-find A-Z herbal monographs • appendices offering important additional information for the safe use of herbal and nutritional supplements, including a list of poison information centres, associations, manufacturers and more • offers clear, comprehensive tables including herb/natural supplement - drug interactions • lists the pharmacological actions of all herbs and natural supplements • a glossary of terms relevant to herbs and natural supplements • two comprehensive new chapters: Herbs and Natural Supplements in Pregnancy and Introduction to Wellness • all chapters completely updated and expanded • ten new monographs taking the total to 130 • now also available as an eBook! A code inside Herbs and Natural Supplements, 3rd Edition: An evidence-based guide enables a full text download, allowing you to browse and search electronically, make notes and bookmarks in the electronic files and highlight material
Category: Medical

Signal Transduction Pathways

Author : Marc Diederich
ISBN : UVA:X030197577
Genre : Cancer
File Size : 22.49 MB
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Keynote speakers at the cell signaling meeting in Luxembourg have provided chapters on hypoxia signal transduction, phosphoserine/threonine-binding domains, targeting of polycomb repressive complexes, conserved signaling mechanisms in innate immunity, and signal transduction by stress-activated MAP kinases. Other topics included among these reports on recent research are receptor signaling, protein kinase cascades as therapeutic targets, cell death in cancer, inflammation-specific signaling, cell signaling pathways leading to regulated chromatin modifications, and transcriptional control. The chapters have been published in four volumes (Part A to D), offering a comprehensive overview about this exciting topic. This third volume focuses on the therapeutic potential for targeting cell signaling mechanisms with particular attention to cell signaling in healthy systems as well as in disease. Cancer therapies and the important area of chemoprevention are included. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member
Category: Cancer

Bioactive Compounds And Cancer

Author : John A. Milner
ISBN : 9781607616276
Genre : Medical
File Size : 36.64 MB
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Because of the wealth of new information generated by the scientific community during the last decade on the role of nutrition on cancer risk, this book provides a forum for presentation and discussion of recent scientific data and highlights a set of dietary recommendations. Bioactive Compounds and Cancer presents chapters that highlight laboratory and clinical findings on how selected nutrients function as signaling molecules and, as such, influence cellular behavior and cancer predisposition. This important compendium focuses on understanding the role of nutrition in cancer biology, the molecular action of bioactive food components and xenobiotics on cancer risk, the role of dietary components in cancer prevention and/or treatment, and nutrition education with the most up to date dietary recommendations that may reduce cancer risk. This volume will be of interest to specialized health professionals, clinicians, nurses, basic and clinical researchers, graduate students, and health officials of public and private organizations.
Category: Medical

Anticancer Research

Author :
ISBN : UCLA:L0090279811
Genre : Cancer
File Size : 32.85 MB
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Category: Cancer