REGULATORY TOXICOLOGY SECOND EDITION

Download Regulatory Toxicology Second Edition ebook PDF or Read Online books in PDF, EPUB, and Mobi Format. Click Download or Read Online button to REGULATORY TOXICOLOGY SECOND EDITION book pdf for free now.

Regulatory Toxicology Second Edition

Author : Shayne C. Gad
ISBN : 142002518X
Genre : Medical
File Size : 60.25 MB
Format : PDF, Kindle
Download : 877
Read : 815

This practical resource provides toxicologists and scientists with essential information on the regulations that govern their jobs and products. Regulatory Toxicology also covers the scientific and historical underpinnings of those regulations. Each chapter provides a grounding in the historical events that led to the development of original legislation and major subsequent changes in legislation. The major administrative divisions for regulatory agencies and their main missions and responsibilities are also detailed, as are the basic filing units or documents the agencies require of individuals to meet goals. This second edition is updated to reflect new developments in the field.
Category: Medical

Handbook Of Toxicology Second Edition

Author : Michael J. Derelanko
ISBN : 0849303702
Genre : Medical
File Size : 89.24 MB
Format : PDF, Docs
Download : 352
Read : 1244

LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLY Working in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single reference source. NEW IN THIS EDITION: Expanded coverage of inhalation toxicology, neurotoxicology, and histopathology Additional regulatory chapters dealing with pesticides, medical devices, consumer products, and world-wide notification of new chemicals Areas of toxicology missing from the first edition such as ecotoxicology and in vitro toxicology A chapter providing extensive overview of the toxicology of metals Two chapters on basic male and female endocrinology and related toxicology Information on differences in physiological and biochemical parameters between children and adults References to Web site sources of valuable information Over 200 new tables and figures THE SINGLE SOURCE FOR THE INFORMATION YOU USE MOST FREQUENTLY Updated and expanded, this unique book includes practical reference information useful to toxicologists in the chemical and pharmaceutical industries, contract laboratories, regulatory agencies, and academia. To help you find information quickly and easily, data is arranged by toxicology subspecialty and each chapter begins with a detailed listing of information presented. Containing over 700 tables and figures, Handbook of Toxicology, Second Edition gives you a single source for the information you use most often.
Category: Medical

In Vitro Toxicology Second Edition

Author : Shayne C. Gad
ISBN : 9781560327691
Genre : Medical
File Size : 66.96 MB
Format : PDF, Docs
Download : 163
Read : 486

Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists a broad range of in vitro models for use in either identifying or understanding most forms of toxicity. The availability of in vitro models spans both the full range of endpoints (irritation, sensitization, lethality, mutagenicity, and devlopmental toxicity) and the full spectrum of target organ systems (skin, eye, heart, liver, kidney, nervous system, etc.). Chapters are devoted to each of these speciality areas from a perspective of presenting the principal models and their uses and limitations. Chapters that overview the principles involved in the general selection and use of models, and that address the issues of safety concerns and regulatory acceptance of these methods are also included.
Category: Medical

Nutritional Toxicology Second Edition

Author : Frank N. Kotsonis
ISBN : 9781420025088
Genre : Medical
File Size : 24.26 MB
Format : PDF, Mobi
Download : 348
Read : 821

Nutrients are gaining recognition for their role in protecting against the toxic effects of free radicals, alcohol and other substances. At the same time, advances in food technology, the appearance of novel foods and new ingredients have generated new toxicological issues and forced health and safety professionals to develop new and more reliable methods to assess their impact on our health. These issues are at the heart of the second edition of Nutritional Toxicology. The book discusses the role of nutrients in protecting the body against toxicants. It explores the overall importance of the metabolism of xenobiotics and antioxidant nutrients in their increasingly important role in protecting against oxidative damage generated by free radicals. The book also discusses components of the diet that can influence metabolism of drugs, how alcohol consumption affects nutritional status, and conversely, how nutritional status affects alcohol metabolism. The effect of age on the body's ability to metabolize drugs and toxicants is discussed in detail.
Category: Medical

Occupational Toxicology Second Edition

Author : Chris Winder
ISBN : 9781420055788
Genre : Technology & Engineering
File Size : 68.4 MB
Format : PDF, ePub, Mobi
Download : 886
Read : 1304

Hazardous agents are an ongoing concern in the modern workplace, with many examples of workers being severely affected by chemicals as a result of both acute and chronic exposure. Occupational Toxicology, 2nd Edition introduces the basics of toxicology that underpin the application of toxicological information to the workplace environment. The book contains chapters on the most important workplace exposures such as metals, pesticides, solvents, plastics, gases, and particulate matter, as well as the organs likely to be affected. The lungs and the skin are given individual consideration as common sites of injury and disease caused by exposure to chemicals. Genotoxicity and cancer are also singled out for particular attention due to ongoing concern about cancer-related effects of chemicals. Important fields interfacing with occupational toxicology - hygiene, epidemiology, and occupational medicine - are also covered to assist the reader in understanding the necessity of cross-discipline considerations in dealing with workplace exposures. This practical approach makes this book particularly valuable to students of toxicology as well as to occupational health and safety professionals at all levels.
Category: Technology & Engineering

Regulatory Toxicology

Author : Shayne C. Gad
ISBN : 0429464738
Genre : BUSINESS & ECONOMICS
File Size : 36.6 MB
Format : PDF, Docs
Download : 275
Read : 502

Category: BUSINESS & ECONOMICS

Clinical Toxicology

Author : Frank A. Barile
ISBN : 9781420092264
Genre : Medical
File Size : 62.26 MB
Format : PDF, ePub, Docs
Download : 153
Read : 1301

Examining the complex interactions associated with clinical toxicological events and chemical exposure of drug administration, this updated and revised Second Edition functions as a stand-alone text or reference of clinical toxicology for professionals, students of toxicology and pharmacy, as well as forensic toxicologists, occupational healthcare workers, industrial hygienists, and safety engineers. This all-inclusive source has been updated to include the latest issues and the most current research in clinical toxicology. Key features in Clinical Toxicology: Principles and Mechanisms include: Convenient and organized categorization of compounds into therapeutic and non-therapeutic agents Tables, drawings, and figures that provide readily accessible, precise data Tables for easy usage and cross-reference to names, indications, effects, adverse reactions, and drug interactions for over 70 common herbal products The brand, generic, and street names of therapeutic agents Topics covered in the Second Edition include: Symptoms of diseases and pathology caused by toxins and clinical drugs Biological and chemical toxins, changes in protocols for managing toxic ingestions, new antidotes, changes in treatments, and the pharmacology and toxicology of herbal products The effects of biological and chemical agents cited by the U.S. and U.N. as potential bioterrorist weapons General physiology and pharmacology principles The widely distributed chemical agents and currently used therapeutic drugs that have hazardous effects
Category: Medical

Casarett Doull S Essentials Of Toxicology Second Edition

Author : Curtis Klaassen
ISBN : 0071766510
Genre : Medical
File Size : 82.39 MB
Format : PDF, ePub, Docs
Download : 437
Read : 1164

The most concise and authoritative introduction to the principles of toxicology and how poisons affect the human body – now in full color A Doody's Core Title ESSENTIAL PURCHASE for 2011! Casarett & Doull’s Essentials of Toxicology is an easy-to-absorb distillation of the field’s gold-standard text Casarett & Doull’s Toxicology: The Basic Science of Poisons. Presented in full color for the first time, the book combines an accessible and engaging approach with coverage of essential introductory concepts to provide you with a solid grounding in basic and medical toxicology. Succinct, yet comprehensive, the text covers essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents – from pesticides to radiation. Features: A complete basic overview of poisons and their clinical management Reflects the expertise of more than fifty renowned contributors A summary of important points is included at the beginning of each chapter and multiple-choice review questions appear at the conclusion Important chapters on forefront topics such as Analytic/Forensic Toxicology, Clinical Toxicology, Occupational Toxicology, Air Pollution, and Ecotoxicology Condensed Table of Contents: General Principles of Toxicology, Disposition of Toxicants, Nonorgan-Directed Toxicity, Target Organ Toxicity, Toxic Agents, Environmental Toxicology, Applications of Toxicology.
Category: Medical

Toxicology Of The Gastrointestinal Tract Second Edition

Author : Shayne Cox Gad
ISBN : 9780429781438
Genre : Medical
File Size : 64.77 MB
Format : PDF, Mobi
Download : 535
Read : 396

The gastrointestinal tract is the most important of the three major routes of entry (and clearance) of xenobiotics and biologic entities into the bodies of mammals. As such, it is also the major route for administration of pharmaceuticals to humans. Gastrointestinal Toxicology, Second Edition describes the mechanism for entry and clearance of xenobiotics, as well as the barriers, immunologic and metabolic issues, and functions present in the GI tract. Appearing in this volume are also considerations of the microbiome and its actions and influence on the function of the GI tract and on the toxicity and pharmacodynamics of ingested substances (including nutrients, toxins, and therapeutics). These fifteen chapters written by experienced experts in the field address methods to evaluate GI function; specifics of GI function and toxicity assessment in canines and minipigs; classes of compounds with their toxicity; species differences; and the toxicity (and promise) of nanoparticles. Those needing to understand the structure, function, and methods of studying the GI tract will find this volume a singular source of reference.
Category: Medical

Ovarian Toxicology Second Edition

Author : Patricia B. Hoyer
ISBN : 9781466504066
Genre : Medical
File Size : 87.81 MB
Format : PDF, ePub
Download : 170
Read : 868

Today, we are exposed to an increasing number of chemicals in the environment and there is a growing awareness of the effects of these chemicals on the ovaries. Infertility resulting from environmental exposures may not be obvious until the reproductive life span is waning. As such, the potential for xenobiotic-induced infertility needs to be better understood. In recent years, research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles is gaining greater appreciation. Ovarian Toxicology, Second Edition represents a compilation of chapters prepared by researchers who have substantially contributed to our understanding of the impact of xenobiotics and environmental factors on ovarian function. The second edition substantially updates newly investigated ovotoxicants as well as improved mechanistic insights that have emerged since the first edition. Topics include: Ovarian physiology and the metabolism of xenobiotics The effect of pesticides, heavy metals, phthalates, BPA, and cigarette smoking on the ovaries Ovarian cancer, including endocrine effects and new perspectives on chemoresistance Epidemiology and human health risk assessment for environmental chemicals and pharmaceuticals The first book to focus specifically on ovarian toxicology, this resource is ideal for scientists in academia, regulatory agencies, and industry who would benefit from a survey of the impact of xenobiotic chemicals on ovarian function.
Category: Medical