Regulation Of Haemoglobin Synthesis

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Regulation Of Haemoglobin Synthesis

Author : J. Neuwirt
ISBN : 9789401010900
Genre : Medical
File Size : 87.38 MB
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Haemoglobin is one of the most important molecules in the animal kingdom. Its function is to carry oxygen to tissues. In lower invertebrates the blood pigment is present in the haemolymph and is not bound in cells. Later in the course of phylo genesis haemoglobin remains associated with cells which produce it and in this form it reaches the peripheral circulation. In higher organisms the haemoglobin production is thus determined by two main factors: haemoglobin synthesis in erythroid cells and the formation of these erythroid cells which depends on cell proliferation in haematopoietic organs. Human haemoglobin is made up of two chains which combine from four different polypeptide chains formed in varying ratios in different periods of the life cycle. During the life span of humans the following haemoglobins are formed: embryonic haemoglobins Gower 1 and 2, foetal haemoglobin F and two adult haemoglobins A and A . E-and IX-chains are part of the embryonic haemoglobins Gower 1 (E4) and 2 Gower 2 (1X2E2). These haemoglobins predominate in embryos during the second month of pregnancy and at the end of the first trimester they are completely re placed by foetal haemoglobin F (~Y2). Adult haemoglobin A consists of two IX and two ~-chains and is the main component of red cells in adults. A relatively small component of red cells accounting for less than 2 % of the total haemo globin, is haemoglobin A2 (1X0).
Category: Medical

Iron Metabolism

Author : Ruth Porter
ISBN : 9780470718018
Genre : Science
File Size : 85.15 MB
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Category: Science

Ecdysone

Author : Mary Bownes
ISBN : 9781483190822
Genre : Medical
File Size : 25.40 MB
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Ecdysone: From Metabolism to Regulation of Gene Expression presents papers from the Seventh Ecdysone Workshop held in Edinburgh, UK from March 31 to April 3, 1985. The book discusses the biosynthesis, distribution, and metabolism of ecdysteroids; the ecdysteroid action and hormone receptors; and the ecdysone inducible genes. The text also describes hormones and oogenesis; the interactions with other hormones, studies on other hormones, and practical applications of ecdysteroid studies.
Category: Medical

Genetics Structure And Function Of Blood Cells

Author : S. R. Hollán
ISBN : 9781483151885
Genre : Science
File Size : 51.14 MB
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Genetics, Structure and Function of Blood Cells contains the proceedings of the symposia of the 28th International Congress of Physiology held in Budapest between 13 and 19 of July, 1980. Organized into six parts, this book begins with a discussion on the genetic regulation of hemoglobin synthesis. Parts II and III describe the immunoglobulin receptors and their effectors, and antenatal development of human blood cells. Subsequent parts talk about regulation of differentiation of hemoglobin structure and function and the role of calcium in red cell membrane transport processes. The last part elucidates the structure and function of blood cell membranes.
Category: Science

Issues In Biochemistry And Geochemistry 2012 Edition

Author :
ISBN : 9781481645720
Genre : Science
File Size : 38.67 MB
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Issues in Biochemistry and Geochemistry / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Inorganic Biochemistry. The editors have built Issues in Biochemistry and Geochemistry: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Inorganic Biochemistry in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biochemistry and Geochemistry: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Category: Science

Medicine And Surgery E Book

Author : Eric KS Lim
ISBN : 9780702040146
Genre : Medical
File Size : 28.17 MB
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This is a stunning new hybrid textbook that has evolved as a direct response to the increasing integration of the two disciplines of medicine and surgery in today's medical curricula. The advantage of this combined approach is it reduces the amount of reading by the elimination of repetition (and inconsistencies) to provide an integrated explanation of the common problems faced both by students during exams and clinicians in daily practice. This book's greatest asset is the ability to illustrate that medical and surgical treatment options are actually part of a continuum in the management of disease. An integrated textbook combining the two major clinical specialities of general medicine and general surgery. Written and edited by a team of physicians and surgeons supported by a team of specialist subject advisors. Puts medicine and surgery in the context of the continuum of disease management and outlines a comprehensive and structured approach to patient management. Adopts a current evidence-based approach with extensive use of national and international guidelines. A full colour textbook with innovative design features and illustrations.
Category: Medical

Health And Ethnicity

Author : Helen Macbeth
ISBN : 0415241677
Genre : Medical
File Size : 58.83 MB
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It is becoming increasingly apparent that certain diseases occur at higher frequencies in different ethnic groups (e.g. Afro-Carribeans and sickle-cell anaemia). The causes for such differences are only just being investigated and the factors involved are clearly both genetic and non-genetic. The biological complexity lies in the interaction of genetic variation and lifestyle differences. Cultural differences range from diet to traditional remedies, from religious beliefs to marriage patterns and much more. This multidisciplinary volume discusses these factors, with contributions from geneticists, medics, anthropologists, epidemiologists and social scientists. Anyone considering variation in health experience due to ethnic factors would be enriched by reading the different perspectives presented in this volume.
Category: Medical

Erythroid Cells

Author : J. Robin Harris
ISBN : 0306434628
Genre : Medical
File Size : 88.70 MB
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This series of books, devoted to aspects of blood cell biochemistry, development, immu nology, and ultrastructure, has evolved and separated from the long-established Plenum series Subcellular Biochemistry. It is the intention of these volumes to draw together related areas of investigation and to provide, in the fullness of time, complete coverage of this rapidly advancing important biomedical discipline. Both fundamental and medically applied topics, dealing with normal and pathological cells, will be included. This, the first volume of the series, contains a diverse collection of chapters, all of which relate to erythroid cells. The range of material included is extremely broad and the authors have used contrasting technical approaches, both within their personal experimen tal studies and within their manuscripts. This has led to the production of a very interest ing compilation, which does, nevertheless, possess a strong overall thematic unity. As with all edited volumes, some topics of importance and interest are not included. This may be because of oversight on my part, as editor, or because the authors originally selected failed to submit their manuscript by the agreed-upon submission date. For these omissions I take full responsibility and trust that at least some of the topics omitted, for instance membrane cation transport systems, will be covered within a future volume of the series. This book commences with two chapters of a developmental nature.
Category: Medical

Clinical Aspects Of Albumin

Author : S.H. Yap
ISBN : 9789400997448
Genre : Medical
File Size : 51.84 MB
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Albumin is the most abundant serum protein produced by the liver. In clinical practice the serum level of albumin continues to be used as an important marker of the presence, progress or ofthe improvement of many diseases, even though it is the complex end result of synthesis, degradation a. nd distribution between intra- and extravascular space. The clinical history of albumin began as early as in 1837, when Ancell first recognized "albumen" and noted that this protein is needed for trans port functions, for maintaining fluidity of the vascular system and for the prevention of edema. However, the important physiological properties of serum proteins and their role in the regulation ofthe oncotic pressure were demonstrated later by the physiologist E. H. Starling in 1895. In 1917 the clinician A. A. Epstein first described the edema in patients with the nephro tic syndrome as being a result of a very low level of serum albumin. Al though the determination of serum albumin concentration became more popular after Howe in 1921 introduced the technique of separation of serum globulins from albumin by sodium sulfate, the first preparations of human serum albumin were made available for clinical use in only 1941 by the development of plasma fractionation by Cohn and his coworkers at Harvard Medical School.
Category: Medical

Male Fertility And Its Regulation

Author : E.S. Hafez
ISBN : 9789400948945
Genre : Medical
File Size : 67.8 MB
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Uncontrolled population growth, a significant problem for many countries, depresses real living standards in all developing areas. As a corollary, un controlled population growth also stresses the ability to deliver adequate reproductive health care on both national and individual levels. To focus on this and related problems an International Congress to examine many aspects of male and female Reproductive Health Center Care was held on 10-15 October 1982 in Maui, Hawaii, USA. This volume is a result of the proceedings from the 'Symposium on Male Fertility and its Regulation' which was a part of the Reproductive Health Care Congress. The organizers of this symposium recognized the need to focus male reproductive understanding on contraceptive development. The ultimate objective was and still is to produce a variety of safe and effective male contraceptives similar to that accomplished in the female. Speakers were invited to review the state of the art in several areas related to male contra ception, reproductive toxicity and reproductive biology. The abstracts of these sessions were published as a special issue of Archives of Andrology (Vol. 9, No.1, August, 1982). Subsequently, this volume was assembled from key papers presented at the Symposium. Additionally, invited man uscripts from leaders in specific areas were solicited to provide additional range to the topics covered.
Category: Medical

Human Genetics

Author : Ruth Porter
ISBN : 9780470718179
Genre : Science
File Size : 29.73 MB
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Category: Science

Genes For Development Cell Growth And Infectious Diseases

Author : Gabriel Gachelin
ISBN : 2742000631
Genre :
File Size : 23.63 MB
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This work which was published to mark the tenth anniversary of the collaboration between the Institut Pasteur and the Riken Institute in Japan, covers a number of research fields in which both laboratories are active: precocious development in mice and the effect on them of disactivating genes, nuclear oncogenes and their role in controlling cell division, and the molecular bases of bacterial and viral infections. There are also chapters dealing with specific aspects of immune recognition, the genetics of sexual determination in humans and a new technique for studying the human genome. This book is intended for researchers and physicians in the fields of immunology, genetics, bacteriology/virology, cancerology, developmental biology, cellular biology and neurobiology.
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Biochemical Actions Of Hormones

Author : Gerald Litwack
ISBN : 9780323146388
Genre : Science
File Size : 84.89 MB
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Biochemical Actions of Hormones, Volume VI is a 10-chapter text that summarizes the regulation of protein kinases and phosphoprotein phosphatases and the relationship of the endocrines to cancer. This volume describes first the precise structures of steroid hormones and carcinogens. The subsequent chapters cover the hormonal regulation of chemical carcinogenesis; the importance of steroid hormones as growth factors for mammary tumors; the effects of steroid hormones in the central nervous system; and the properties of the purified estrogen receptor. A chapter highlights the biochemical actions of neurohypophysial hormones and neurophysin. Another chapter presents the biochemistry and physiology of cytokinin, a plant hormone. The final chapter exemplifies the multihormonal systems by control of the α2u-globulin produced in the liver. This book will be of great value to endocrinologists.
Category: Science

Genes In Medicine

Author : I. Rasko
ISBN : 0412373408
Genre : Medical
File Size : 70.77 MB
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This stimulating book bridges the gap between molecular biology and human genetics. Specifically written for medical students and human geneticists, it is a valuable guide to a rapidly moving field.
Category: Medical