Metchnikoff And The Origins Of Immunology

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Metchnikoff And The Origins Of Immunology

Author : Alfred I. Tauber
ISBN : 019534510X
Genre : Medical
File Size : 57.59 MB
Format : PDF
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This fascinating intellectual history is the first critical study of the work of Elie Metchnikoff, the founding father of modern immunology. Metchnikoff authored and championed the theory that phagocytic cells actively defend the host body against pathogens and diseased cells. His program developed from comparative embryological studies that sought to establish genealogical relations between species at the dawn of the Darwinian revolution. In this scientific biography, Tauber and Chernyak explore ore Metchnikoff's development as an embryologist, showing how it prepared him to propose his theory of host-pathogen interaction. They discuss the profound impact of Darwin's theory of evolution on Metchnikoff's progress, and the influence of 19th century debates on vitalism, teleology, and mechanism. As a case study of scientific discovery, this work offers lucid insight into the process of creative science and its dependence on cultural and philosophic sources. Immunologists and historians of science and medicine will find it an absorbing and accessible account of a remarkable individual.
Category: Medical
Metchnikoff and the Origins of Immunology
Language: en
Pages: 247
Authors: Alfred I. Tauber, Leon Chernyak
Categories: Medical
Type: BOOK - Published: 1991 - Publisher: Oxford University Press on Demand

"Important. . . .This book comes at an opportune time because it shows us that to understand the origins of immunology, we must look into the profound intellectual and social changes that were occurring in the 19th century." --New England Journal of Medicine
Language: en
Pages: 304
Authors: Alfred I. Tauber
Categories: Science
Type: BOOK - Published: 2017-01-02 - Publisher: Oxford University Press

Modern immunology traditionally conceives of the immune system as providing defense against pathogens. Alfred I. Tauber criticizes this conception of immunity as too narrow, because it discounts much of the immune system's other normal functions. These include active tolerance of nutritional exchanges with the environment and the stabilization of cooperative
The Generation of Diversity
Language: en
Pages: 508
Authors: Alfred I. Tauber, Scott H. Podolsky
Categories: Science
Type: BOOK - Published: 2000 - Publisher: Harvard University Press

This book is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period. In recent years immunology has been one of the most exciting--and successful--fields of biomedical research; this book provides essential background for understanding the conceptual conflicts occurring in the
The Evolutionary Biology Papers of Elie Metchnikoff
Language: en
Pages: 230
Authors: H. Gourko, D. Williamson, A.I. Tauber
Categories: History
Type: BOOK - Published: 2013-04-17 - Publisher: Springer Science & Business Media

Elie Metchnikoff (1845-1916), winner of the Nobel Prize in 1907 for his contributions to immunology, was first a comparative zoologist, who, working in the wake of Darwin's On the Origin of Species, made seminal contributions to evolutionary biology. His work in comparative embryology is best known in regard to the
Organism and the Origins of Self
Language: en
Pages: 384
Authors: A.I. Tauber
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

"De la vaporisation et de la centralisation du Moi. Tout est la. " Charles Baudelaire (journal entry) This anthology is my visit to Oz. On sabbatical in 1988, I chose to reeducate myself in general biology, first broadening my erudition as an immunologist, and then extending that horizon into evolutionary