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Isolation And Purification Of Proteins

Author : Rajni Hatti-Kaul
ISBN : 0203911687
Genre : Science
File Size : 85.71 MB
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This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.
Category: Science

Natural Products Isolation

Author : Richard J. P. Cannell
ISBN : 9780896033627
Genre : Science
File Size : 51.92 MB
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Natural Products Isolation provides a comprehensive introduction to techniques for the extraction and purification of natural products from all biological sources. Geared to scientists with little experience of natural products extraction, but offering even skilled researchers valuable advice and insight, Natural Products Isolation lays the foundation for the potential extractor to isolate natural substances efficiently. Its methods and guidance will almost certainly play a major role in today's natural product discovery and development.
Category: Science

Natural Products Isolation

Author : Satyajit D. Sarker
ISBN : 9781592599554
Genre : Medical
File Size : 50.14 MB
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Natural Products Isolation: Second Edition presents a practical overview of just how natural products can be extracted, prepared, and isolated from the source material. Maintaining the main theme and philosophy of the first edition, this second edition incorporates all the new significant developments in this field of research. The chapters are divided into four distinct sections: introduction, extraction, chromatography, and special topics. This second edition provides substantial backround information for natural product researchers and will prove a useful reference guide to all of the available techniques.
Category: Medical

Infection Control In Home Care

Author : Emily Rhinehart
ISBN : 0834211432
Genre : Medical
File Size : 46.3 MB
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Provides information to home care and hospice organizations for the prevention, control, and surveillance of infection. Thirteen chapters cover topics including infection control as a health care discipline; the infectious disease process; patient care practices; infection control in home infusion t
Category: Medical

Handbook Of Isolation And Characterization Of Impurities In Pharmaceuticals

Author : Satinder Ahuja
ISBN : 012044982X
Genre : Medical
File Size : 43.13 MB
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The United States Food and Drug Administration (FDA) and other regulatory bodies around the world require that impurities in drug substance and drug product levels recommended by the International Conference on Harmonisation (ICH) be isolated and characterized. Identifying process-related impurities and degradation products also helps us to understand the production of impurities and assists in defining degradation mechanisms. When this process is performed at an early stage, there is ample time to address various aspects of drug development to prevent or control the production of impurities and degradation products well before the regulatory filing and thus assure production of a high-quality drug product. This book, therefore, has been designed to meet the need for a reference text on the complex process of isolation and characterization of process-related (synthesis and formulation) impurities and degradation products to meet critical requlatory requirements. It's objective is to provide guidance on isolating and characterizing impurities of pharmaceuticals such as drug candidates, drug substances, and drug products. The book outlines impurity identification processes and will be a key resource document for impurity analysis, isolation/synthesis, and characterization. - Provides valuable information on isolation and characterization of impurities. - Gives a regulatory perspective on the subject. - Describes various considerations involved in meeting regulatory requirements. - Discusses various sources of impurities and degredation products.
Category: Medical

The End Of An Isolation

Author : Harish Kapur
ISBN : 9024730813
Genre : Social Science
File Size : 80.76 MB
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Category: Social Science

A Guide To Protein Isolation

Author : C. Dennison
ISBN : 1402012241
Genre : Science
File Size : 81.90 MB
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It is a truism of science that the more fundamental the subject, the more universally applicable it is. Neverthelens, it is important to strike a level of "fundamentalness" appropriate to the task in hand. For example, an in-depth study of the mechanics of motor cars would tell one nothing about the dynamics of traffic. Traffic exists on a different "level" - it is dependent upon the existence of motor vehicles but the physics and mathematics of traffic can be adequately addressed by considering motor vehicles as mobile "blobs", with no consideration of how they become mobile. To start a discourse on traffic with a consideration of the mechanics of motor vehicles would thus be inappropropriate. In writing this volume, I have wrestled with the question of the appropriate level at which to address the physics underlying many of the techniques used in protein isolation. I have tried to strike a level as would be used by a mechanic (with perhaps a slight leaning towards an engineer) - i.e. a practical level, offering appropriate insight but with minimal mathematics. Some people involved in biochemical research have a minimal grounding in chemistry and physics and so I have tried to keep it as simple as possible.
Category: Science

The Cinema Of Isolation

Author : Martin F. Norden
ISBN : 0813521041
Genre : Performing Arts
File Size : 51.8 MB
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Filmmakers have often encouraged us to regard people with physical disabilities in terms of pity, awe, humor, or fearas "Others" who somehow deserve to be isolated from the rest of society. In this first history of the portrayal of physical disability in the movies, Martin Norden examines hundreds of Hollywood movies (and notable international ones), finds their place within mainstream society, and uncovers the movie industry's practices for maintaining the status quokeeping people with disabilities dependent and "in their place." Norden offers a dazzling array of physically disabled characters who embody or break out of the stereotypes that have both influenced and been symptomatic of societys fluctuating relationship with its physically disabled minority. He shows us "sweet innocents" like Tiny Tim, "obsessive avengers" like Quasimodo, variations on the disabled veteran, and many others. He observes the arrival of a new set of stereotypes tied to the growth of science and technology in the 1970s and 1980s, and underscores movies like My Left Foot and The Waterdance that display a newfound sensitivity. Nordens in-depth knowledge of disability history makes for a particularly intelligent and sensitive approach to this long-overlooked issue in media studies.
Category: Performing Arts