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Author : James D. Murray
ISBN : 0387952233
Genre : Mathematics
File Size : 69.63 MB
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Mathematical Biology is a richly illustrated textbook in an exciting and fast growing field. Providing an in-depth look at the practical use of math modeling, it features exercises throughout that are drawn from a variety of bioscientific disciplines - population biology, developmental biology, physiology, epidemiology, and evolution, among others. It maintains a consistent level throughout so that graduate students can use it to gain a foothold into this dynamic research area.

Author : Linda J. S. Allen
ISBN : 0130352160
Genre : Mathematics
File Size : 34.92 MB
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KEY BENEFIT: This reference introduces a variety of mathematical models for biological systems, and presents the mathematical theory and techniques useful in analyzing those models. Material is organized according to the mathematical theory rather than the biological application. Contains applications of mathematical theory to biological examples in each chapter. Focuses on deterministic mathematical models with an emphasis on predicting the qualitative solution behavior over time. Discusses classical mathematical models from population , including the Leslie matrix model, the Nicholson-Bailey model, and the Lotka-Volterra predator-prey model. Also discusses more recent models, such as a model for the Human Immunodeficiency Virus - HIV and a model for flour beetles. KEY MARKET: Readers seeking a solid background in the mathematics behind modeling in biology and exposure to a wide variety of mathematical models in biology.

This book is based on a one semester course that the authors have been teaching for several years, and includes two sets of case studies. The first includes chemostat models, predator-prey interaction, competition among species, the spread of infectious diseases, and oscillations arising from bifurcations. In developing these topics, readers will also be introduced to the basic theory of ordinary differential equations, and how to work with MATLAB without having any prior programming experience. The second set of case studies were adapted from recent and current research papers to the level of the students. Topics have been selected based on public health interest. This includes the risk of atherosclerosis associated with high cholesterol levels, cancer and immune interactions, cancer therapy, and tuberculosis. Readers will experience how mathematical models and their numerical simulations can provide explanations that guide biological and biomedical research. Considered to be the undergraduate companion to the more advanced book "Mathematical Modeling of Biological Processes" (A. Friedman, C.-Y. Kao, Springer – 2014), this book is geared towards undergraduate students with little background in mathematics and no biological background.

Author : S. I. Rubinow
ISBN : 0486425320
Genre : Mathematics
File Size : 70.19 MB
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Designed to explore the applications of mathematical techniques and methods related to biology, this text explores five areas: cell growth, enzymatic reactions, physiological tracers, biological fluid dynamics and diffusion. Topics essentially follow a course in elementary differential equations — some linear algebra and graph theory; requires only a knowledge of elementary calculus.

Author : Edward K. Yeargers
ISBN : 9781475710953
Genre : Mathematics
File Size : 82.3 MB
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Biology is a source of fascination for most scientists, whether their training is in the life sciences or not. In particular, there is a special satisfaction in discovering an understanding of biology in the context of another science like mathematics. Fortunately there are plenty of interesting (and fun) problems in biology, and virtually all scientific disciplines have become the richer for it. For example, two major journals, Mathematical Biosciences and Journal of Mathematical Biology, have tripled in size since their inceptions 20-25 years ago. The various sciences have a great deal to give to one another, but there are still too many fences separating them. In writing this book we have adopted the philosophy that mathematical biology is not merely the intrusion of one science into another, but has a unity of its own, in which both the biology and the math ematics should be equal and complete, and should flow smoothly into and out of one another. We have taught mathematical biology with this philosophy in mind and have seen profound changes in the outlooks of our science and engineering students: The attitude of "Oh no, another pendulum on a spring problem!," or "Yet one more LCD circuit!" completely disappeared in the face of applications of mathematics in biology. There is a timeliness in calculating a protocol for ad ministering a drug.

Author : Ronald W. Shonkwiler
ISBN : 9780387709840
Genre : Science
File Size : 59.20 MB
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This text presents mathematical biology as a field with a unity of its own, rather than only the intrusion of one science into another. The book focuses on problems of contemporary interest, such as cancer, genetics, and the rapidly growing field of genomics.

Author : Brian P. Ingalls
ISBN : 9780262018883
Genre : Science
File Size : 35.28 MB
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An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Author : Nicholas F. Britton
ISBN : 9781447100492
Genre : Mathematics
File Size : 83.23 MB
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This self-contained introduction to the fast-growing field of Mathematical Biology is written for students with a mathematical background. It sets the subject in a historical context and guides the reader towards questions of current research interest. A broad range of topics is covered including: Population dynamics, Infectious diseases, Population genetics and evolution, Dispersal, Molecular and cellular biology, Pattern formation, and Cancer modelling. Particular attention is paid to situations where the simple assumptions of homogenity made in early models break down and the process of mathematical modelling is seen in action.

Author : James Sneyd
ISBN : 0821867644
Genre : Medical
File Size : 36.51 MB
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In many respects, biology is the new frontier for applied mathematicians. This book demonstrates the important role mathematics plays in the study of some biological problems. It introduces mathematicians to the biological sciences and provides enough mathematics for bioscientists to appreciate the utility of the modelling approach. The book presents a number of diverse topics, such as neurophysiology, cell biology, immunology, and human genetics. It examines how research is done,what mathematics is used, what the outstanding questions are, and how to enter the field. Also given is a brief historical survey of each topic, putting current research into perspective. The book is suitable for mathematicians and biologists interested in mathematical methods in biology.

Author : G. Dunn
ISBN : 9780486151366
Genre : Science
File Size : 45.67 MB
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For students of mathematical biology, an introduction to taxonomic characters, measurement of similarity, analysis of principal components, multidimensional scaling, cluster analysis, identification and assignment techniques, and the construction of evolutionary trees.

Author : Elizabeth S. Allman
ISBN : 0521525861
Genre : Mathematics
File Size : 65.50 MB
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Linear and non-linear models of populations, molecular evolution, phylogenetic tree construction, genetics, and infectious diseases are presented with minimal prerequisites.

Author : Yang Kuang
ISBN : 9781498785532
Genre : Mathematics
File Size : 86.14 MB
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Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.

This book is an introduction to mathematical biology for students with no experience in biology, but who have some mathematical background. The work is focused on population dynamics and ecology, following a tradition that goes back to Lotka and Volterra, and includes a part devoted to the spread of infectious diseases, a field where mathematical modeling is extremely popular. These themes are used as the area where to understand different types of mathematical modeling and the possible meaning of qualitative agreement of modeling with data. The book also includes a collections of problems designed to approach more advanced questions. This material has been used in the courses at the University of Trento, directed at students in their fourth year of studies in Mathematics. It can also be used as a reference as it provides up-to-date developments in several areas.

Author : D.S. Jones
ISBN : 9781420083583
Genre : Mathematics
File Size : 86.40 MB
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Deepen students' understanding of biological phenomenaSuitable for courses on differential equations with applications to mathematical biology or as an introduction to mathematical biology, Differential Equations and Mathematical Biology, Second Edition introduces students in the physical, mathematical, and biological sciences to fundamental modeli

Author : Edward A. Bender
ISBN : 048641180X
Genre : Mathematics
File Size : 67.36 MB
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Accessible text features over 100 reality-based examples pulled from the science, engineering and operations research fields. Prerequisites: ordinary differential equations, continuous probability. Numerous references. Includes 27 black-and-white figures. 1978 edition.

Author : Edward Batschelet
ISBN : 9783642618697
Genre : Mathematics
File Size : 44.91 MB
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From the reviews: "...Here we have a book which we can wholeheartedly suggest. The mathematics is sound and pared to essentials; the examples are an impressive, well-chosen selection from the biomathematics literature, and the problem sets provide both useful exercises and some fine introductions to the art of modeling... Batschelet has written an introduction to biomathematics which is notable for its clarity - not only a clarity of presentation, but also a clarity of purpose, backed by a sure grasp of the field..." #Bulletin of Mathematical Biology#1 "For research workers in the biomedical field who feel a need for freshening up their knowledge in mathematics, but so far have always been frustrated by either too formal or too boring textbooks, there is now exactly what they would like to have: an easy to read introduction. This book is highly motivating for practical workers because only those mathematical techniques are offered for which there is an application in the life sciences. The reader will find it stimulating that each tool described is immediately exemplified by problems from latest publications." #Int. Zeitschrift für klinische Pharmakologie, Therapie und Toxikologie#2

Author : Edward Beltrami
ISBN : 9780124046931
Genre : Social Science
File Size : 25.9 MB
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Mathematical Models for Society and Biology, 2e, is a useful resource for researchers, graduate students, and post-docs in the applied mathematics and life science fields. Mathematical modeling is one of the major subfields of mathematical biology. A mathematical model may be used to help explain a system, to study the effects of different components, and to make predictions about behavior. Mathematical Models for Society and Biology, 2e, draws on current issues to engagingly relate how to use mathematics to gain insight into problems in biology and contemporary society. For this new edition, author Edward Beltrami uses mathematical models that are simple, transparent, and verifiable. Also new to this edition is an introduction to mathematical notions that every quantitative scientist in the biological and social sciences should know. Additionally, each chapter now includes a detailed discussion on how to formulate a reasonable model to gain insight into the specific question that has been introduced. Offers 40% more content – 5 new chapters in addition to revisions to existing chapters Accessible for quick self study as well as a resource for courses in molecular biology, biochemistry, embryology and cell biology, medicine, ecology and evolution, bio-mathematics, and applied math in general Features expanded appendices with an extensive list of references, solutions to selected exercises in the book, and further discussion of various mathematical methods introduced in the book