Hcv The Journey From Discovery To A Cure

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Hcv The Journey From Discovery To A Cure

Author : Michael J. Sofia
ISBN : 3030283992
Genre : Science
File Size : 53.20 MB
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​Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide. It is also one of the major causes of liver cancer and liver transplants. The elucidation of the HCV genome, and the development of a whole cell system to study the virus spurred the search for novel direct acting antiviral drugs to cure this disease. This global effort culminated in the development of direct acting antiviral drugs that led to cure rates approaching 100% in all patient populations after only 8-12 weeks of therapy. These efforts resulted in one of the greatest achievements in public health and provides the potential for eliminating HCV as a major disease worldwide. This volume is aimed at a broad audience of academic and industrial scientists interested in the discovery and development of drugs to treat viral diseases and those interested in reading about one of the most unique accomplishments in biomedical research. The volume will provide a one of a kind reference work that highlights the many efforts, from the discovery of the HCV virus, to the invention of breakthrough medicines and their use in the real world to cure patients. It is the companion book to the volume "HCV: The Journey from Discovery to a Cure - Volume I".
Category: Science
HCV: The Journey from Discovery to a Cure
Language: en
Pages: 500
Authors: Michael J. Sofia
Categories: Science
Type: BOOK - Published: 2020-02-08 - Publisher: Springer

​Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide. It is also one of the major causes of liver cancer and liver transplants. The elucidation of the HCV genome, and the development of a whole cell system to study
HCV: The Journey from Discovery to a Cure
Language: en
Pages: 463
Authors: Michael J. Sofia
Categories: Science
Type: BOOK - Published: 2019-11-23 - Publisher: Springer Nature

Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide. It is also one of the major causes of liver cancer and liver transplants. The elucidation of the HCV genome, and the development of a whole cell system to study
HCV: The Journey from Discovery to a Cure
Language: en
Pages: 500
Authors: Michael J. Sofia
Categories: Science
Type: BOOK - Published: 2020-02-07 - Publisher: Springer Nature

​Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide. It is also one of the major causes of liver cancer and liver transplants. The elucidation of the HCV genome, and the development of a whole cell system to study
Successful Strategies for the Discovery of Antiviral Drugs
Language: en
Pages: 534
Authors: Manoj C. Desai, Nicholas A. Meanwell, David E. Thurston
Categories: Medical
Type: BOOK - Published: 2013 - Publisher: Royal Society of Chemistry

A volume that will be aimed at medicinal chemistry and emerging drug discovery scientists. The book will be organized according to the various strategies deployed for the discovery and optimization of initial lead compounds. It will be broken down into four main sections: phenotypic and biochemical screening, structure and physical
Innovative Drug Synthesis
Language: en
Pages: 360
Authors: Jie Jack Li, Douglas S. Johnson
Categories: Science
Type: BOOK - Published: 2015-11-05 - Publisher: John Wiley & Sons

This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting-edge science associated with them. Following the editors’ 3 successful drug synthesis books, this provides expert analysis of the pros and cons of different synthetic routes and demystifies the process of modern drug discovery for