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Author : Mehdi Tavassoli
ISBN : 9781461244943
Genre : Medical
File Size : 36.2 MB
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In 1868, Ernst Neumann recognized that blood cells re quire continuous replenishment during postnata1life. Before him, the assumption was that cells of the blood, like nerves once formed in the embryo, remain in the body throughout life. Neumann also recognized that this process occurred within the bone marrow, because this tissue provided a fa vorable environment for proliferation and differentiation of blood cell precursors. Vera Danchakoff, the Russian embryologist working in the US, in 1916 made an analogy to the soil and the seed. Bone marrow forms the soil, providing a favorable environment for the growth of seed, the hemopoietic stem cell, and other progenitor cells. Imagine in the remote past a heap of similar tree seeds. These seeds develop in our moderate climate into a tall and many branched tree. Suppose the wind bears a part of the seeds away and brings them to a land possessing different environmental conditions, we will say the arc tic lands. There the seeds may develop but they may pro duce trees no higher than our moss.
Author : Stewart Sell
ISBN : 9781461476962
Genre : Science
File Size : 29.75 MB
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This book discusses critical areas of progress in stem cell research, including the most recent research and applications of pluripotent embryonic cells, induced pluripotent cells, oligopotent tissue stem cells and cancer stem cells. The text covers basic knowledge of stem cell biology, stem cell ethics, development of techniques for applying stem cell therapy, the technology of obtaining appropriate cells for transplantation as well as the role of stem cells in cancer and how therapy may be directed to cancer stem cells. This new volume is essential reading for all scientists currently in the field or allied research areas, and those for those graduate students who envision a career in stem cells.
Author : John P. Greer
ISBN : 0781765072
Genre : Medical
File Size : 43.80 MB
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Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology continues to be an industry leader with its ability to correlate basic science with the clinical practice of hematology. With the first edition of Wintrobe's Clinical Hematology published in 1942 clearly establishing hematology as a distinct subspecialty of Internal Medicine, the latest edition continues the influence of the Wintrobe name and helps to set this book apart from the competition.With its strong focus on the clinical aspects of hematology, the book has generated a strong following among internists and general practitioners who want a single resource to consult for their patients who present any blood related disorder. The Twelfth Edition is in full color for the first time, boasts a new editorial team, and includes expanded coverage of new medications and four new chapters on Newborn Anemias, Pathology of LHC, Spleen Tumors, and Myeloproliferative Disorders and Mast Cell Disease. A companion Website will offer the fully searchable text and an image bank.
Author : Robert Lanza
ISBN : 0080533736
Genre : Science
File Size : 26.61 MB
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New discoveries in the field of stem cell research have frequently appeared in the news and in scientific literature. Research in this area promises to lead to new therapies for cancer, heart disease, diabetes, and a wide variety of other diseases. This two-volume reference integrates this exciting area of biology, combining the prerequisites for a general understanding of adult and embryonic stem cells, the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations, as well as a presentation by the world's experts of what is currently known about each specific organ system. The editors of the Handbook of Stem Cells include: Robert Lanza, Helen Blau, John Gearhart, Brigid Hogan, Douglas Melton, Malcolm Moore, Roger Pedersen, E. Donnall Thomas, James Thomson, Catherine Verfaillie, Irving Weissman, and Michael West. The Editorial Board includes: W. French Anderson, Peter Andrews, Anthony Atala, Jose Cibelli, Giulio Cossu, Robert Edwards, Martin Evans, Elaine Fuchs, Margaret Fuller, Fred Gage, Richard Gardner, Margaret Goodell, Ronald Green, William Haseltine, Joseph Itskovitz-Eldor, Rudolf Jaenisch, Ihor Lemischka, Dame Anne McLaren, Richard Mulligan, Stuart Orkin, Martin Pera, Benjamin Reubinoff, Janet Rossant, Hans Scholer, Austin Smith, Evan Snyder, Davor Solter, Alan Trounson, and Leonard Zon. This comprehensive set should be a much-needed addition to the library of students and researchers alike. * Provides comprehensive coverage on this highly topical subject * Contains contributions by the foremost authorities and premiere names in the field of stem cell research * The accompanying CD-ROM includes over 250 color figures
Author : Owen N. Witte
ISBN : 0879694068
Genre : Medical
File Size : 66.88 MB
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Ten articles cover a broad range of concepts to be considered in the study of leukemia, such as the mechanisms regulating the hierarchy of primitive hematopoietic cells, avian erythroblastosis as a model to study oncogene cooperation in leukemia, and an antidote to programmed cell death. Published f
Author : William Joseph Williams
ISBN : MINN:31951D01100892D
Genre : Blood
File Size : 84.85 MB
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This edition features comprehensive coverage of the basic sciences, clinical manifestations, diagnostic approaches and treatment of diseases of blood cells, coagulation, proteins and thrombosis. All chapters are written by leaders in the field, and are edited to ensure a consistent and complementary treatment of subjects throughout. It includes over 50% new material, and the latest information on sickle cell diseases, AIDS, Von Willebrand disease, chronic myelogenous leukemia and more. The emphasis is on what the clinican needs to know for effective patient management.
Author : Kenneth Kaushansky
ISBN : 9780071833011
Genre : Medical
File Size : 20.71 MB
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Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2019! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.
Author : Leslie J. DeGroot
ISBN : 0721642659
Genre : Medical
File Size : 57.67 MB
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Revised throughout, the 5th Edition of this leading reference presents a complete and up-to-date review and analysis of all aspects of endocrinology, diabetes, and bone metabolism. Readers will also find state-of-the-art information on genetics, proteinomics, and hormone signaling, and coverage of the field's hottest topics in nearly 20 new chapters. Joined by an international team of leading expertsmany new to this editionDrs. Jameson and DeGroot provide guidance that integrates the basic science of endocrinology with clinical medicine and the practical management of endocrine disorders. A clinical focus emphasizes diagnosis and therapy.
Author : Joseph D. Bronzino
ISBN : 0849383463
Genre : Medical
File Size : 60.82 MB
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The first handbook ever written for the biomedical engineering field, this text contains comprehensive information on every aspect of biomedical engineering. It reflects the current perception of the field as one that encompasses emerging and expanding disciplines of investigation and application. It includes a complete review of the major physiological systems and accepted practices.
