Genomes And What To Make Of Them

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Genomes And What To Make Of Them

Author : Barry Barnes
ISBN : 9781459605930
Genre : Genomes
File Size : 75.48 MB
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The announcement in 2003 that the Human Genome Project had completed its map of the entire human genome was heralded as a stunning scientific breakthrough: our first full picture of the basic building blocks of human life. Since then, boasts about the benefits - and warnings of the dangers - of genomics have remained front-page news, with everyone agreeing that genomics has the potential to radically alter life as we know it. For the nonscientist, the claims and counterclaims are dizzying - what does it really mean to understand the genome? Barry Barnes and John Dupr offer an answer to that question and much more in Genomes and What to Make of Them, a clear and lively account of the genomic revolution and its promise. The book opens with a brief history of the science of genetics and genomics, from Mendel to Watson and Crick and all the way up to Craig Venter; from there the authors delve into the use of genomics in determining evolutionary paths - and what it can tell us, for example, about how far we really have come from our ape ancestors. Barnes and Dupr then consider both the power and risks of genetics, from the economic potential of plant genomes to overblown claims that certain human genes can be directly tied to such traits as intelligence or homosexuality. Ultimately, the authors argue, we are now living with a new knowledge as powerful in its way as nuclear physics, and the stark choices that face us - between biological warfare and gene therapy, a new eugenics or a new agricultural revolution - will demand the full engagement of both scientists and citizens. Written in straightforward language but without denying the complexity of the issues, Genomes and What to Make of Them is both an up-to-date primer and a blueprint for the future.
Category: Genomes

Blossoms And The Genes That Make Them

Author : Maxine F. Singer
ISBN : 9780198811138
Genre : Science
File Size : 84.7 MB
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Flowers evolved to attract pollinators, so new generations of plant can form. But how do plants know when to bloom, and how do they construct their flowers? This book describes what we have learnt of the astonishing genetic and epigenetic processes behind the dazzling variety of flower shapes, colours, and scents.--
Category: Science

Wired For Culture Origins Of The Human Social Mind

Author : Mark Pagel
ISBN : 9780393063158
Genre : Science
File Size : 62.85 MB
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“Does an excellent job of using evolutionary biology to discuss the origins of religion, music, art, and . . . morality.”—Publishers Weekly, starred review A unique trait of the human species is that our personalities, lifestyles, and worldviews are shaped by an accident of birth—namely, the culture into which we are born. It is our cultures and not our genes that determine which foods we eat, which languages we speak, which people we love and marry, and which people we kill in war. But how did our species develop a mind that is hardwired for culture—and why? Evolutionary biologist Mark Pagel tracks this intriguing question through the last 80,000 years of human evolution, revealing how an innate propensity to contribute and conform to the culture of our birth not only enabled human survival and progress in the past but also continues to influence our behavior today. Shedding light on our species’ defining attributes—from art, morality, and altruism to self-interest, deception, and prejudice—Wired for Culture offers surprising new insights into what it means to be human.
Category: Science

Fungal Genomics

Author :
ISBN : 0080527450
Genre : Science
File Size : 66.91 MB
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The purpose of this volume is to highlight wide-ranging applications of genomics in the area of applied mycology and biotechnology. The volume covers: a brief overview on fungal genomics; meiotic recombination in fungi; molecular genetics of circadian rhythms; genome sequencing; transposable elements; mitochondrial genomes; ribosome biogenesis; pathogenicity genes; genetic improvement of yeasts; microarrays: techniques and applications; fungal germplasm and data bases. Although it is difficult to develop a comprehensive volume on fungal genomics because of the range and complexity of the emerging knowledge, an attempt has been made to bring together pertinent information that will serve the needs of the reader, provide a quick reference to material that might otherwise be difficult to locate, and furnish a starting point for further study.
Category: Science

Computational Methods In Genome Research

Author : International Symposium on Computational Methods in Genome Research (1992 : Heidelberg)
ISBN : 0306447126
Genre : Medical
File Size : 22.64 MB
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Can computational science keep up with evolving technology for genome mapping and sequencing?; Informatics and experiments for the human genome project; Data management tools for scientific applications: framework, status, and genomic applications; The ACEDB genome database; The integrated genomic database (IGD); Genetic mapping, an overview; Representing genomic maps in a relational database; Livermore's pragmatic approach to integrated mapping for chromosome 19; Searching protein sequence databases - is optimal best?; Algorithmic advances for searching biosequence databases; Pattern recognition in genomic and protein sequences: a survey of statistical validation problems; New algorithms for the computational of evolutionary phylogenetic trees; Modelling protein structure from remote sequence similarity: an approach to tertiary structure prediction; Genetic algorithms in protein structure prediction; Applications of artificial neural networks in genome research; Statistical models of chromosome evolution; Deciphering the genetic message: some thoughts onf present limits.
Category: Medical

Introduction To Computational Genomics

Author : Nello Cristianini
ISBN : 9781139460156
Genre : Computers
File Size : 82.60 MB
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Where did SARS come from? Have we inherited genes from Neanderthals? How do plants use their internal clock? The genomic revolution in biology enables us to answer such questions. But the revolution would have been impossible without the support of powerful computational and statistical methods that enable us to exploit genomic data. Many universities are introducing courses to train the next generation of bioinformaticians: biologists fluent in mathematics and computer science, and data analysts familiar with biology. This readable and entertaining book, based on successful taught courses, provides a roadmap to navigate entry to this field. It guides the reader through key achievements of bioinformatics, using a hands-on approach. Statistical sequence analysis, sequence alignment, hidden Markov models, gene and motif finding and more, are introduced in a rigorous yet accessible way. A companion website provides the reader with Matlab-related software tools for reproducing the steps demonstrated in the book.
Category: Computers

Viruses And Human Disease

Author : Ellen G. Strauss
ISBN : 0080553168
Genre : Science
File Size : 69.16 MB
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Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss’ virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia Further reading sections at the end of each chapter make it easy find key references World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text
Category: Science

Chemistry And The Human Genome

Author : Ted Lister
ISBN : 0854043969
Genre : Science
File Size : 39.99 MB
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This resource aims to show the chemical science behind the discovery for post-16 students of chemistry and biology, and places it in the context of science in the 21st century.
Category: Science

Biology For The Ib Diploma

Author : Andrew Allott
ISBN : 019914818X
Genre : Biology
File Size : 68.44 MB
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This concise guide provides all the content you need for the IB Diploma in Biology at both Standard and Higher Level.* Follows the structure of the IB Programme exactly and include all the options* Each topic is presented on its own page for clarity* Standard and Higher Level material clearly indicated* Plenty of practice questions* Written with an awareness that English may not be the reader's first language
Category: Biology

Foundations Of Comparative Genomics

Author : Arcady R. Mushegian
ISBN : 0080546099
Genre : Science
File Size : 29.81 MB
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This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. Presents an historic overview of genome biology and its achievements Includes topics not covered in other books such as minimal and ancestral genomes Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level Critically reviews horizontal gene transfer and other contentious issues Covers comparative virology as a somewhat overlooked foundation of modern genome science
Category: Science

Manipulation Of The Avian Genome

Author : Robert J. Etches
ISBN : 0849342163
Genre : Nature
File Size : 55.27 MB
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Many genes have been cloned from chicken cells, and during the next decade numerous laboratories will be concentrating their resources in developing ways of using these tools. Manipulation of the Avian Genome contains the most recent information from leading research laboratories in the areas of developmental and molecular genetics of the chicken. This information was presented at the Keystone Symposium held at Lake Tahoe in March, 1991. The book discusses potential applications of emerging technology in basic science and poultry production. Various techniques for altering genomic DNA, such as microinjection, retroviral vectors, and lipofection are covered. Genome evaluation using DNA fingerprinting and conventional breeding techniques are presented.
Category: Nature

Genomic Medicine

Author : Great Britain: Parliament: House of Lords: Science and Technology Committee
ISBN : 0108444511
Genre : Medical
File Size : 88.71 MB
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Recent developments in genomic science stemming from the sequencing of the human genome represent a unique opportunity for real advances in medical care and the Government and the NHS must take a range of steps to ensure that these advances are realised. The Government should produce a new White Paper with details on: how the Department of Health will facilitate the translation of advances in genomic science into clinical practice, including the operational changes needed to bring genetic testing into mainstream clinical practice; a roadmap for how such developments will be incorporated into the NHS; proposals for a programme of sustained long-term funding to support these measures. A range of genetic tests are already being used within the NHS to improve the diagnosis and treatment of a range of common illnesses, but there are barriers to the translation of new tests from invention through to use. The Committee looks specifically at the growing market for Direct to Consumer Tests (DCTs) and raises concerns about the effect of consumers receiving DCT results via the internet without proper medical advice to put those results in context. The Committee supports a voluntary code of practice for DCT providers. Ensuring NHS staff have adequate training in genomic medicine will be vital, and training in using and interpreting genetic tests should be an integral part of training for healthcare workers. The report recognises that there are privacy concerns about the retention and use of genetic data as well as apprehension about how the data may be used by, for example the insurance industry.
Category: Medical

Trading The Genome

Author : Bronwyn Parry
ISBN : 0231121741
Genre : Business & Economics
File Size : 44.14 MB
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"In a work that draws on anthropology, history, philosophy, business, and law, Bronwyn Parry links a firsthand investigation of the operation of the bioprospecting industry to an analysis of broader economic, regulatory, and technological transformations: the rise of an information economy, global intellectual property rights and benefit-sharing regimes, and the progressive molecularization of approaches to biological research. Parry reveals how a failure to monitor this new global trade in bio-information could have potentially disastrous consequences for the suppliers of genetic and biochemical resources - transforming the complex dynamics of collecting, as well as the politics and practice of biological resource exploitation."--BOOK JACKET.
Category: Business & Economics

Red Rising And Philosophy

Author : Courtland Lewis
ISBN : 9780812699548
Genre : Philosophy
File Size : 57.6 MB
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Red Rising and Philosophy has gathered together a crew of the wisest Helldivers philosophy can offer. Could humanity's love of physical enhancements cause its extinction? Do people doom humanity by trying to all be the same? Can a person love someone, while at the same time wanting that person destroyed? Is equality always the best principle on which to organize society? What is evil, and how does it exist in contemporary life? Does one remain the same person, even after changing every physical aspect of one's body? Is it moral to sell oneself into slavery, whether it’s through sex or manual labor? Is it ethical to sell one's children into slavery, on the promise that their children will live in peace and tranquility? These questions and more are what make Brown’s Red Rising trilogy such an impactful story. Brown pulls no punches, and philosophy works best in such an environment. Red Rising and Philosophy is not for the timid or the faint at heart. It’s not The Passage, since no one will die from reading it, but reading it could be a life-changing experience.
Category: Philosophy

Exploring Horizons For Domestic Animal Genomics

Author : National Research Council
ISBN : 9780309085052
Genre : Science
File Size : 34.94 MB
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Recognizing the important contributions that genomic analysis can make to agriculture, production and companion animal science, evolutionary biology, and human health with respect to the creation of models for genetic disorders, the National Academies convened a group of individuals to plan a public workshop that would: (1) assess these contributions; (2) identify potential research directions for existing genomics programs; and (3) highlight the opportunities of a coordinated, multi-species genomics effort for the science and policymaking communities. Their efforts culminated in a workshop sponsored by the U.S. Department of Agriculture, Department of Energy, National Science Foundation, and the National Institutes of Health. The workshop was convened on February 19, 2002. The goal of the workshop was to focus on domestic animal genomics and its integration with other genomics and functional genomics projects.
Category: Science

From Genes To Genomes

Author : Jeremy W. Dale
ISBN : 9781119954279
Genre : Science
File Size : 72.10 MB
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The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation. The new edition features: Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics. Clear, two-colour diagrams throughout. A dedicated website including all figures. Noted for its outstanding balance between clarity of coverage and level of detail, this book provides an excellent introduction to the fast moving world of molecular genetics.
Category: Science

Ocr A2 Biology Student Unit Guide Unit F215 Control Genomes And Environment

Author : Richard Fosbery
ISBN : 9781444155419
Genre : Science
File Size : 20.16 MB
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Student Unit Guides are perfect for revision. Each guide is written by an examiner and explains the unit requirements, summarises the relevant unit content and includes a series of specimen questions and answers. There are three sections to each guide: Introduction - includes advice on how to use the guide, an explanation of the skills being tested by the assessment objectives, an outline of the unit or module and, depending on the unit, suggestions for how to revise effectively and prepare for the examination questions. Content Guidance - provides an examiner's overview of the module's key terms and concepts and identifies opportunities to exhibit the skills required by the unit. It is designed to help students to structure their revision and make them aware of the concepts they need to understand the exam and how they might analyse and evaluate topics. Question and Answers - sample questions and with graded answers which have been carefully written to reflect the style of the unit. All responses are accompanied by commentaries which highlight their respective strengths and weaknesses, giving students an insight into the mind of the examiner.
Category: Science

The Rough Guide To Genes Cloning

Author : Rough Guides
ISBN : 9781848362246
Genre : Science
File Size : 64.59 MB
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What exactly is a gene? How does cloning actually work? Are designer babies a bad idea? Could we ever clone a human? The Rough Guide To Genes & Cloning answers all these questions and more. From the inside story of cells and their structure and the sleuths who cracked the genetic code to DNA cloning, twins and Dolly the sheep. Illustrated throughout with helpful pictures and diagrams, this Rough Guide turns the microscope on the things that make us what we are.
Category: Science

Life As We Do Not Know It

Author : Peter Ward
ISBN : 9781440628566
Genre : Science
File Size : 76.51 MB
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An engrossing and revelatory first look at the search for alien life—on Earth and beyond For the past twenty years, Peter Ward has been at the forefront of popular science writing, with books such as the influential and controversial Rare Earth. In Life as We Do Not Know It, Ward, with his signature blend of eloquence, humor, and learned insight, vividly details the latest scientific findings, cutting-edge research, and intrepid new theories on the subject of alien life and the possible extraterrestrial origins of life on Earth. In lucid, entertaining, and bold prose, Peter Ward once again challenges our notions of life on earth (and beyond).
Category: Science

Genes A Very Short Introduction

Author : Jonathan Slack
ISBN : 9780191664182
Genre : Science
File Size : 48.41 MB
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In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. Explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also used by forensic scientists to identify individuals in crime. He also explores issues such as the role of genetic heritability and IQ as well as the changes that occur in the genes of populations during evolution. An ideal guide for anyone curious about what genes are and how genetics can be put to use, this Very Short Introduction demonstrates the ways in which the gene concept has been understood and used by molecular biologists, population biologists, and social scientists around the world. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Category: Science