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Against Expression

Author : Craig Dworkin
ISBN : 9780810127111
Genre : Language Arts & Disciplines
File Size : 74.38 MB
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Charles Bernstein has described conceptual "poetry pregnant with thought." Against Expression, the premier anthology of conceptual writing, presents work that is by turns thoughtful, funny, provocative, and disturbing. Editors Craig Dworkin and Kenneth Goldsmith chart the trajectory of the conceptual aesthetic from early precursors such s Samuel Beckett and Marcel Duchamp through major avant-garde groups of the past century, including Dada, Oulipo, Fluxus, and language poetry, to name just a few. The works of more than a hundred writers from Aasprong to Zykov demonstrate a remarkable variety of new ways of thinking about the nature of texts, information, and art, using found, appropriated, and randomly generated texts to explore the possibilities of non-expressive language.
Category: Language Arts & Disciplines

Freedom Of Expression

Author : Glen Newey
ISBN : 9781443806343
Genre : Political Science
File Size : 65.48 MB
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Freedom of expression has long been cherished as a liberal ideal. But in the political climate of the new millennium free expression finds itself under assault. Muslims greeted the publication by a Danish newspaper of cartoons depicting the prophet Muhammad with outrage. The Pope was forced to issue an apology after Muslims denounced his remarks about a Byzantine emperor as anti-Islamic. Meanwhile in the UK, the play Behzti was cancelled after protests by Sikhs and Christian activists attempted to force the BBC not to screen Jerry Springer: the Opera. The political establishment, as well as religious activists, has also tried to gag free speech. Moves to ban inciting religious hatred and “glorifying” acts of terrorism, have stirred up political ferment. In several jurisdictions Holocaust denial is already outlawed. The advent of the internet, with its lack of regulation, has fuelled long-standing feminist concerns about pornography. Child pornography has become rampant on the web. This collection explores the new challenges to free expression posed by cultural and political conflict and by technological change. It asks whether classical and modern liberalism still carry conviction against challenges to liberal orthodoxy. The contributors ask how to weigh the claims of free expression against other fundamental rights such as group membership, personal privacy, and the protection of the public sphere both as a discursive realm, and as a cultural space. Together they tackle the key questions facing free expression today: What does free expression mean in an age of global communications? How, if at all, can it be traded against other goods? Can free speech survive, given the growing awareness of its costs?
Category: Political Science

Beta Catenin And Ha Ras Master Regulators Of Zonal Gene Expression In Mouse Liver

Author : Albert Braeuning
ISBN : 9783832520045
Genre :
File Size : 42.83 MB
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Hepatocytes located in the periportal or perivenous regions of the liver lobule have different, often complementary functions, as indicated by differences in the content and activity of various enzymes of the intermediary and xenobiotic metabolism. The signaling molecules mediating this metabolic zonation, however, are largely unknown. Based on the correlation of marker protein expression between perivenous hepatocytes and Ctnnb1 (encoding beta-catenin)-mutated mouse hepatomas and between periportal hepatocytes and Ha-ras-mutated hepatomas, a hypothesis was developed postulating that two opposing signals, a Wnt-signal maybe delivered by endothelial cells of the central veins activating a beta-catenin-dependent pathway, and a second signal delivered by blood-borne molecules activating Ras-dependent downstream cascades, regulate gene expression in hepatocytes from the periportal and perivenous domains of the liver lobule.The impact of beta-catenin and Ras signaling on zonal gene expression was analyzed in vivo by use of different transgenic mouse strains. Zone-specific physiological activation and antagonism of the two pathways were demonstrated. Transcriptome profiles of Ctnnb1- and Ha-ras-mutated tumors closely resembled those of perivenous and periportal hepatocytes. In vitro experiments with primary hepatocytes and hepatoma cells confirmed the role of beta-catenin signaling in the induction of "perivenous" gene expression, particularly of drug-metabolizing enzymes. Inducibility of drug-metabolizing enzymes by xenobiotics was demonstrated to be modulated by beta-catenin in vitro and in vivo. beta-catenin thereby activated transcription by both direct beta-catenin/ TCF-dependent and indirect mechanisms.Serum components were shown to inhibit beta-catenin-mediated transcription and to induce the expression of "periportal" markers. Serum-mediated inhibition of beta catenin signaling was not exclusively linked to Ras activation, but also to the action of different ligand-activated nuclear receptors, thus suggesting a complex interplay of different blood-borne molecules in the periportal repression of beta catenin signaling.In summary, the results favor the hypothesis that gene expression patterns in periportal and perivenous hepatocytes are regulated, at least in part, by Ras- and beta catenin-dependent signaling pathways. In the perivenous areas of the liver lobule, beta catenin seems to act as a master regulator of both basal and inducible expression of enzymes involved in the metabolism of drugs and xenobiotics.

American Literature In Transition 2000 2010

Author : Rachel Greenwald Smith
ISBN : 9781108548656
Genre : Literary Criticism
File Size : 72.51 MB
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American Literature in Transition, 2000–2010 illuminates the dynamic transformations that occurred in American literary culture during the first decade of the twenty-first century. The volume is the first major critical collection to address the literature of the 2000s, a decade that saw dramatic changes in digital technology, economics, world affairs, and environmental awareness. Beginning with an introduction that takes stock of the period's major historical, cultural, and literary movements, the volume features accessible essays on a wide range of topics, including genre fiction, the treatment of social networking in literature, climate change fiction, the ascendency of Amazon and online booksellers, 9/11 literature, finance and literature, and the rise of prestige television. Mapping the literary culture of a decade of promise and threat, American Literature in Transition, 2000–2010 provides an invaluable resource on twenty-first century American literature for general readers, students, and scholars alike.
Category: Literary Criticism

Facilitating Emotional Change

Author : Laura N. Rice
ISBN : 1572302011
Genre : Psychology
File Size : 25.67 MB
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Using an experiential therapy framework, the authors show how to work with moment-by-moment emotional processes to resolve various psychological difficulties.
Category: Psychology

Microsoft Excel Vba Professional Projects

Author : Duane Birnbaum
ISBN : 1592000657
Genre : Computers
File Size : 24.42 MB
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Microsoft Excel VBA Professional Projects illustrates and teaches intermediate to advanced techniques in VBA programming using Microsoft's Excel spreadsheet application. It provides an introduction to VBA and Excel VBA before proceeding through four to five programming projects using Excel to illustrate basic and advanced programming techniques. It does not assume any prior knowledge of Excel VBA programming.
Category: Computers

Dance And The Lived Body

Author : Sondra Horton Fraleigh
ISBN : 0822971704
Genre : Performing Arts
File Size : 61.23 MB
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In her remarkable book, Sondra Horton Fraleigh examines and describes dance through her consciousness of dance as an art, through the experience of dancing, and through the existential and phenomenological literature on the lived body. She describes, with performance photographs, specific imagery in dance masterworks by Doris Humphrey, Anna Sokolow, Viola Farber, Nina Weiner, and Garth Fagan.
Category: Performing Arts

Aesthetic Theory

Author : Theodor W. Adorno
ISBN : 0485300699
Genre : Philosophy
File Size : 76.46 MB
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The most important aesthetics of the century, this is a long-awaited work, the culmination of a lifetime's investigation. Among the twelve major sections are Art, Society, Aesthetics; the Categories of the Ugly, the Beautiful, the Technics; Natural Beauty; Coherence and Subject-Object; Towards a Theory of the Artwork.
Category: Philosophy

Freedom Of Expression And The Internet

Author : Prof. Wolfgang Benedek
ISBN : 9789287178381
Genre : Law
File Size : 89.39 MB
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With the rise of the Internet, the opportunities to express oneself have grown exponentially, as have the challenges to freedom of expression. From the Arab Spring to the global Occupy movement, freedom of expression on the Internet has had a profound impact on the debates which shape our future. At the same time, an increasing number of states use the Internet to spy on journalists and citizens, to prosecute and jail bloggers, and to censor online information. This book sets out to answer essential questions regarding the extent and limits of freedom of expression online. It seeks to shed light on the often obscure landscape of what we are allowed to say online and how our ideas, and the process of imparting and receiving information, are protected. It shows the large ambit of rights protected by freedom of expression – including freedom of the media and the right to access information via the Internet. It also highlights the importance of the standard-setting, monitoring and promotion activities of international and non-governmental organisations, with a chapter on relevant national practices that illustrates how different states deal with the challenge that the Internet has brought to ensuring freedom of expression for all. As the importance of the Internet in our daily lives grows, readers will find this book to be a valuable resource for understanding the rights and obligations of each actor on the Internet, including states, Internet companies and civil society.
Category: Law