Adverse Effects Of Engineered Nanomaterials

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Adverse Effects Of Engineered Nanomaterials

Author : Bengt Fadeel
ISBN : 9780123869401
Genre : Medical
File Size : 62.59 MB
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An essential reference that discusses occupational exposure and the adverse health effects of engineered nanomaterials and highlights current and future biomedical applications of these nanomaterials in relation to nanosafety. Multi-authored book written by leading US and European experts on nanotoxicology and nanomedicine Discusses the health implications and a clinical translation of experimental data in this area Takes a schematic, non-exhaustive approach to summarize the most important research data in this field Includes a glossary, with a brief explanation of the term and with a reference to where the term or phrase has been used will be included within the book
Category: Medical

Handbook Of Immunological Properties Of Engineered Nanomaterials

Author : Marina A. Dobrovolskaia
ISBN : 9789814390255
Genre : Medical
File Size : 21.61 MB
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The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.
Category: Medical

Engineered Nanoparticles

Author : Ashok K Singh
ISBN : 9780128014929
Genre : Medical
File Size : 88.10 MB
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Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity is an indispensable introduction to engineered nanomaterials (ENM) and their potential adverse effects on human health and the environment. Although research in the area of pharmacology and toxicology of ENM is rapidly advancing, a possible correlation between their physicochemical properties and biomedical properties or toxicity is not yet fully understood. This understanding is essential to develop strategies for the safe applications and handling of ENM. The book comprehensively defines the current understanding of ENM toxicity, first describing these materials and their physicochemical properties, and then discussing the toxicological theory and methodology before finally demonstrating the potential impact of ENM on the environment and human health. It represents an essential reference for students and investigators in toxicology, pharmacology, chemistry, material sciences, medicine, and those in related disciplines who require an introduction to ENM and their potential toxicological effects. Provides state-of-the-art physicochemical descriptions and methodologies for the characterization of engineered nanomaterials (ENM) Describes the potential toxicological effects of ENM and the nanotoxicological mechanisms of action Presents how to apply theory to practice in a public health and risk assessment setting
Category: Medical

Nanotoxicity

Author : Saura C. Sahu
ISBN : 9780470747797
Genre : Science
File Size : 71.56 MB
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Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials. Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include: biomarkers for nanotoxicity assessment nanotoxicity assessment by gene expression analysis in vivo and in vitro models for nanotoxicity testing mechanisms of nanotoxicity pharmakokinetics of nanomaterials nanotoxicity of foods including food processing, food packaging and food safety nanotoxicity of drugs including drug development and drug delivery nanotoxicity of cosmetics and consumer products health and environmental impact of nanotoxicity safety evaluation of nanomaterials regulatory impact of nanomaterials Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.
Category: Science

Nanotoxicology

Author : Nancy A. Monteiro-Riviere
ISBN : 1420045156
Genre : Medical
File Size : 53.57 MB
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Nanomaterials - structures with characteristic dimensions between 1 and 100 nm -exhibit a variety of unique and tunable chemical and physical properties that have made engineered nanoparticles central components in an array of emerging technologies. The use of nanotechnology is increasing; however its potential adverse effects on human health are n
Category: Medical

Nanotechnology Toxicological Issues And Environmental Safety

Author : P.P. Simeonova
ISBN : 9781402060762
Genre : Technology & Engineering
File Size : 67.45 MB
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This book provides a summary of the state-of-art knowledge on nanomaterials and nanoparticles. It examines toxicological issues, risk assessment and control measures, public participation and educational/ethical issues, as well as institutional mechanisms and status reports from various countries. Coverage also details collaborations in the field of nanotechnology regarding safe application and development.
Category: Technology & Engineering

Handbook Of Nanosafety

Author : Ulla Vogel
ISBN : 9780124166622
Genre : Medical
File Size : 29.93 MB
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Handbook of Nanosafety: Measurement, Exposure and Toxicology, written by leading international experts in nanosafety, provides a comprehensive understanding of engineered nanomaterials (ENM), current international nanosafety regulation, and how ENM can be safely handled in the workplace. Increasingly, the importance of safety needs to be considered when promoting the use of novel technologies like ENM. With its use of case studies and exposure scenarios, Handbook of Nanosafety demonstrates techniques to assess exposure and risks and how these assessments can be applied to improve workers' safety. Topics covered include the effects of ENM on human health, characterization of ENM, aerosol dynamics and measurement, exposure and risk assessment, and safe handling of ENM. Based on outcomes from the NANODEVICE initiative, this is an essential resource for those who need to apply current nanotoxicological thinking in the workplace and anyone who advises on nanosafety, such as professionals in toxicology, occupational safety and risk assessment. Multi-authored book, written by leading researchers in the field of nanotoxicology and nanosafety Features state-of-the-art physical and chemical characterization of engineered nanomaterials (ENM) Develops strategies for exposure assessment, risk assessment and risk management Includes practical case studies and exposure scenarios to demonstrate how you can safely use ENM in the workplace
Category: Medical

Phytotoxicity Of Nanoparticles

Author : Mohammad Faisal
ISBN : 9783319767086
Genre : Science
File Size : 28.18 MB
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This book provides relevant findings on nanoparticles’ toxicity, their uptake, translocation and mechanisms of interaction with plants at cellular and sub-cellular level. The small size and large specific surface area of nanoparticles endow them with high chemical reactivity and intrinsic toxicity. Such unique physicochemical properties draw global attention of scientists to study potential risks and adverse effects of nanoparticles in the environment. Their toxicity has pronounced effects and consequences for plants and ultimately the whole ecosystem. Plants growing in nanomaterials-polluted sites may exhibit altered metabolism, growth reduction, and lower biomass production. Nanoparticles can adhere to plant roots and exert physicochemical toxicity and subsequently cell death in plants. On the other hand, plants have developed various defense mechanisms against this induced toxicity. This books discusses recent findings as well as several unresolved issues and challenges regarding the interaction and biological effects of nanoparticles. Only detailed studies of these processes and mechanisms will allow researchers to understand the complex plant-nanomaterial interactions.
Category: Science

Case Studies In Nanotoxicology And Particle Toxicology

Author : Antonietta M Gatti
ISBN : 9780128012543
Genre : Medical
File Size : 38.85 MB
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Case Studies in Nanotoxicology and Particle Toxicology presents a highly-illustrated analysis of the most prominent cases on the adverse effects of nanoparticles and their impact on humans and the environment. This comprehensive reference demonstrates the possible risks imposed by managing and handling nanoparticles, showing the effects of involuntary inhalation or ingestion during their use and after their incineration. Through the use of numerous examples, readers will discover the possible risks and effects of working with nanoparticles, along with best practices to prevent these effects. The text is an essential reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians. Presents real-life cases showing the potential risks to human health following exposure to nanoparticles An ideal reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians Provides examples to help assess risks of handling engineered nanomaterials Advises on the best forms of protection and the safest nanotechnological products
Category: Medical

Safety Aspects Of Engineered Nanomaterials

Author : Wolfgang Luther
ISBN : 9789814364867
Genre : Science
File Size : 50.7 MB
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With contributions from leading researchers and government experts involved with the safety assessment of nanomaterials, this book gives an up-to-date review on the safety of engineered nanomaterials and their impact on health and the environment. It covers the whole nanomaterial life cycle—from production, transport, and distribution in the environment to biological responses and toxicology. The book also addresses occupational safety measures as well as societal and economic contexts, such as medical applications of nanomaterials, public acceptance, and risk communication and management.
Category: Science

Nanomaterials In Drug Delivery Imaging And Tissue Engineering

Author : Ashutosh Tiwari
ISBN : 9781118644744
Genre : Science
File Size : 83.23 MB
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This groundbreaking, multidisciplinary work is one of the first books to cover Nanotheragnostics, the new developmental edge of nanomedicine. Through a collection of authoritative chapters, the book reports on nanoscopic therapeutic systems that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities. An invaluable reference for researchers in materials science, bioengineering, pharmacy, biotechnology, and nanotechnology, this volume features four main parts on biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and nanoscaffolds technology.
Category: Science

Nanotechnology

Author : Iris Eisenberger
ISBN : 9781786608949
Genre : Philosophy
File Size : 22.38 MB
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Rooted in different disciplines such as ethics, ecology, law, social and political sciences, this volume explore the normative approaches, societal practices, and legal mechanisms which have emerged in the nano-field over the last two decades.
Category: Philosophy

The Year In Neurology 2

Author : Richard T. Johnson
ISBN : 9781573317801
Genre : Medical
File Size : 81.79 MB
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This second volume in The Year in Neurology series focuses on present reviews covering novel approaches to our understanding neurological diseases through both basic science and clinical approaches. A wide-range of topics is covered within this volume, including: vertebrobasilar dolichoectasia neurological nanotechnology neurologic diseases sleep disorders chronic inflammatory diseases NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Category: Medical

Interaction Of Nanomaterials With The Immune System

Author : James C. Bonner
ISBN : 9783030339623
Genre : Medical
File Size : 72.5 MB
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This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative testing strategies for evaluating immunotoxicity of ENMs.
Category: Medical

Environmental Nanotechnology Applications And Impacts Of Nanomaterials Second Edition

Author : Mark Wiesner
ISBN : 9780071828451
Genre : Technology & Engineering
File Size : 62.26 MB
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Extensively revised and featuring new material, this timely, advanced resource covers the impacts of nanomaterials on organisms and ecosystems and their applications within industry. Cowritten by leaders of two of the most prominent research groups in the world considering the effects of nanomaterials on the environment, the second edition of Environmental Nanotechnology addresses the cutting-edge advances in this area. There is now much more known about the impacts of nanomaterials on organisms and ecosystems. Methods have been developed where there were few accepted procedures in the past. Thinking has evolved to consider the life cycle effects of nanomaterial production, and tools for risk forecasting are now under development. There has also been some experience among academics in using this book as the basis for new courses on Environmental Nanotechnology. Three new chapters cover the life cycle of nanomaterial fabrication and use and estimating nanomaterial exposure in the environment. A systematic discussion of the effects of nanomaterials on organisms and ecosystems is included, where the previous edition was largely limited to speculation. Features 75% new material New chapter on the life cycle aspects of nanomaterial fabrication and use Two new chapters on estimating nanomaterial exposure in the environment: implications that explore nanotoxicology; exposure estimation Contains end-of-chapter problems and questions
Category: Technology & Engineering

Inorganic Nanoprobes For Biological Sensing And Imaging

Author : Hedi Mattoussi
ISBN : 9781596931978
Genre : Technology & Engineering
File Size : 42.1 MB
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This groundbreaking resource offers you an up-to-date account of the pioneering activity pushing new boundaries in the emerging area of inorganic nanoprobes and their use in biology and medicine. Written and edited by leading experts in the field, this unique book places particular emphasis nanoprobes made of luminescent semiconductor nanocrystals (quantum dots or QDs) and magnetic nanoparticles (MNPs). You find an insightful discussion on the synthesis, characterization, and analysis of the unique properties of luminescent QDs and MNPs.
Category: Technology & Engineering

Environmental Policy Law

Author : Holly D. Doremus
ISBN : STANFORD:36105064230183
Genre : Law
File Size : 79.19 MB
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This casebook takes a very broad view of environmental law, encompassing the regulation of private and public land use and protection of wildlife as well as pollution control and remediation. It provides sufficient breadth for any introductory environmental or natural resources law course. It also strikes a balance by focusing in detail on those portions of the statutes covered that raise particularly interesting or important conceptual issues. Throughout, it highlights perpetual controversies such as the nature of human relationships to nature and the appropriate extent of individual control over natural resource use. The Fifth Edition includes problems that help students develop and test their facility with the materials in the text and the concepts underlying those materials. The new edition will also have new chapters on international environmental law issues and on enforcement issues.
Category: Law

Nanoscience And Nanotechnology

Author : Vicki H. Grassian
ISBN : STANFORD:36105131758711
Genre : Science
File Size : 69.81 MB
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This comprehensive book covers various aspects of nanoscience and nanotechnology and what is known about the potential environmental and health impacts. Divided into three main sections, the book addresses the toxicity of nanomaterials, fate and transport of nanomaterials in the environment, and occupational health aspects of nanotechonology.
Category: Science