Advances In Controlled Delivery Of Drugs

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Advances In Controlled Delivery Of Drugs

Author : Melvyn Kohudic
ISBN : 1566761948
Genre : Medical
File Size : 62.56 MB
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The development of improved methods of drug delivery has received significant attention over the last two decades. Most important is a non-toxic level of the drug at a particular body organ or body locale. To reach this goal, many variations of controlled release have been researched worldwide. This edited volume of papers from the Journal of Biomaterials Applications details many exciting technical advances in controlled release drug delivery systems. Some of the important developments described in the book include implantable delivery systems, delivery of topical drugs, and ultrasonic drug delivery.
Category: Medical

Advances In Nanochemoprevention

Author : Rishi Paliwal
ISBN : 9789811596926
Genre : Medical
File Size : 22.65 MB
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This book discusses the recent progress and advances in nanochemoprevention. Chemoprevention utilizes natural dietary compounds and has regained interest due to larger safety window and proven efficacy of such molecules in cancer treatments. Nanotechnology has revolutionized drug delivery through passive as well as active targeting. This book provides a comprehensive overview of phytochemical bioactives that are used in chemoprevention. It gives a comprehensive overview of the variety of natural molecules and types of nanoparticles as well as mechanistic aspects of their superior efficacy over plain drug molecules. The book concludes with summarizing the progress of pre-clinical results of developed formulations for cancer treatment using nano-chemoprevention.
Category: Medical

Drug Delivery Research Advances

Author : Boris O. Mashkevich
ISBN : 160021732X
Genre : Medical
File Size : 59.54 MB
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Drug delivery is a term that refers to the delivery of a pharmaceutical compound to humans or animals. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Many medications, however, can not be delivered using these routes because they might be susceptible to degradation or are not incorporated efficiently. For this reason many protein and peptide drugs have to be delivered by injection. For example, many immunisations are based on the delivery of protein drugs and are often done by injection. Current efforts in the area of drug delivery include the development of targeted delivery in which the drug is only active in the target area of the body (for example, in cancerous tissues) and sustained release formulations in which the drug is released over a period of time in a controlled manner from a formulation. This new book focuses on worldwide research on drug delivery and targeting at the molecular, cellular, and higher levels.
Category: Medical

Recent Advances In Drug Delivery Systems

Author : James M. Anderson
ISBN : 9781461327455
Genre : Medical
File Size : 33.37 MB
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The evident rapid expansion of scientific work and intense interest in both experimental and clinical aspects of new drug delivery systems provided strong motivation for planning this symposium. In designing the program, speakers were identified for their particular expertise in a wide range of topics such as dermal delivery systems, pro-drugs, oral prolonged release, rate-controlled drug delivery, the pharmacokinetics of drug release systems, the synthesis of polymeric drug carriers and the refinement of drug delivery pumps. Because of the considerable involvement of diverse scientists from laboratories around the world where investigations relevant to the topic are now being pursued, a deliberate effort was made to invite international leaders in the field to share their knowledge and experimental outcomes. Thus, plenary papers and panel discussions were offered by organic chemists, bioengineers, patholo gists, material scientists, physical chemists, and pharmacokineti cists from academic and industrial laboratories in some dozen countries. This book which records the presentations offered at the sym posium covers a broad array of topics ranging from general overviews of the physicochemical concepts and analytical methodology which underpin the refinement of drug delivery systems and the tissue responses associated with the use of such systems through detailed discussions of a variety of current approaches employed in the development of new systems.
Category: Medical

Controlled Release In Oral Drug Delivery

Author : Clive G. Wilson
ISBN : 1461410045
Genre : Medical
File Size : 52.10 MB
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Controlled Release in Oral Drug Delivery provides focus on specific topics, complementing other books in the initial CRS series. Each chapter sets the context for the inventions described and describe the latitude that the inventions allow. In order to provide some similar look to each chapter, the coverage includes the historical overview, candidate drugs, factors influencing design and development, formulation and manufacturing and delivery system design. This volume was written along three main sections: the relevant anatomy and physiology, a discussion on candidates for oral drug delivery and the major three groups of controlled release systems: diffusion control (swelling and inert matrices); environmental control (pH sensitive coatings, time control, enzymatic control, pressure control) and finally lipidic systems.
Category: Medical

Controlled Drug Delivery

Author : Kinam Park
ISBN : UOM:39015049701272
Genre : Medical
File Size : 68.66 MB
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Controlled Drug Delivery examines the current state of drug deliverytechnologies and discusses the future directions of drug delivery development.Topics include advances for increasing the uptake of orally delivered drugs,modulating blood levels for better drug safety/efficacy profiles, targetingdrugs and genes for cellular and intracellular delivery, improving the deliveryof poorly soluble drugs and recent advances in polymer-based drug deliverytechnologies.
Category: Medical

Arch Int Pharmacodyn Ther

Author :
ISBN : SRLF:AA0003603487
Genre : Drugs
File Size : 85.7 MB
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Summaries at end of articles.
Category: Drugs

Therapeutic Systems

Author : Klaus Heilmann
ISBN : UOM:39015003226035
Genre : Biopharmaceutics
File Size : 74.27 MB
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Category: Biopharmaceutics

Controlled Release Systems

Author : Alex van Herk
ISBN : 9789814613224
Genre : Medical
File Size : 54.74 MB
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In the area of controlled release of active substances, such as drugs, a strong interest in nanoparticles as carriers of active ingredients has arisen. Some of the active components are extremely hydrophobic, without cellular permeability and susceptible to metabolic degradation. Owing to this, their use is limited. This kind of agent can be transported without any problem through physiological media by using nanoparticles. The size of particles is an important parameter because it governs the efficiency of the delivery system. For this type of application, particles that have a diameter smaller than 1 μm are especially useful. Polymeric nanoparticles that have diameters in the colloidal range are produced by means of polymerization processes in dispersed media. Drugs are taken up into the nanoparticles by adsorption, absorption, or “entrapment," or covalent bonding and they are delivered (release) by desorption, diffusion, polymer degradation, or a combination of these mechanisms. Nanoparticles (including nanogels) that release their contents by external triggering open up new possibilities for therapeutic strategies. External triggering by light, heat, change in pH, or application of ultrasound opens up the possibility to release the material on demand. If only a part of the wall of the nanoparticle (nanocapsule) is responsive, we are dealing with the so-called nanobottles, a nanocontainer with the active substance and a lid on the container that can be "opened" and "closed" by external triggering. This book focuses on responsive nanoparticles and brings together two interesting areas: nanoparticles and responsive polymers. The concept of the book is that of a systematic approach from nanoparticles synthesis via responsive polymers to nanobottles. The second part of the book presents contributions from experts in the field and provides a state-of-the-art overview of the field.
Category: Medical

Oral Controlled Release Formulation Design And Drug Delivery

Author : Hong Wen
ISBN : 1118060326
Genre : Science
File Size : 45.88 MB
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This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.
Category: Science

Federation Proceedings

Author : Federation of American Societies for Experimental Biology
ISBN : UVA:X001087613
Genre : Biochemistry
File Size : 38.95 MB
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Category: Biochemistry

Controlled Pulmonary Drug Delivery

Author : Hugh D.C. Smyth
ISBN : 1441997458
Genre : Medical
File Size : 34.32 MB
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The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.
Category: Medical

Microfluidics And Biomems

Author : Carlos H. Mastrangelo
ISBN : 0819442887
Genre : Technology & Engineering
File Size : 36.13 MB
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Category: Technology & Engineering

Clinical Pharmacology

Author : Mauri Mattila
ISBN : UOM:39015003232439
Genre : Anticonvulsants
File Size : 46.11 MB
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Category: Anticonvulsants

Journal Of Reproduction And Fertility

Author :
ISBN : NWU:35558003681000
Genre : Fertility
File Size : 28.61 MB
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Includes the Proceedings of the Society for the Study of Fertility.
Category: Fertility

Biopolymers In Drug Delivery Recent Advances And Challenges

Author : Michael U. Adikwu
ISBN : 9781608050789
Genre : Biopolymers
File Size : 33.3 MB
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"This Ebook describes the applicability of diverse natural and synthetic biopolymers and their blends in drugs, vaccines and gene delivery. It would serve as a concise body of information on biopolymers for researchers, industries and students of pharmaceu"
Category: Biopolymers

Good Packaging

Author :
ISBN : UCLA:L0050971159
Genre : Containers
File Size : 76.97 MB
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Category: Containers