THE ROLE OF SPHINGOLIPIDS IN CANCER DEVELOPMENT AND THERAPY 117 ADVANCES IN CANCER RESEARCH

Download The Role Of Sphingolipids In Cancer Development And Therapy 117 Advances In Cancer Research ebook PDF or Read Online books in PDF, EPUB, and Mobi Format. Click Download or Read Online button to THE ROLE OF SPHINGOLIPIDS IN CANCER DEVELOPMENT AND THERAPY 117 ADVANCES IN CANCER RESEARCH book pdf for free now.

The Role Of Sphingolipids In Cancer Development And Therapy

Author :
ISBN : 9780123944139
Genre : Science
File Size : 56.29 MB
Format : PDF, Docs
Download : 403
Read : 1070

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "The Role of Sphingolipids in Cancer Development and Therapy" Provides invaluable information on the exciting and fast-moving field of cancer research This thematic volume looks at "The Role of Sphingolipids in Cancer Development and Therapy" Outstanding and original reviews
Category: Science

Sphingolipids As Signaling And Regulatory Molecules

Author : Charles Chalfant
ISBN : 1441967419
Genre : Science
File Size : 76.61 MB
Format : PDF, ePub
Download : 405
Read : 687

This book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation and infectious diseases.
Category: Science

Bioactive Sphingolipids In Cancer Biology And Therapy

Author : Yusuf A. Hannun
ISBN : 9783319207506
Genre : Medical
File Size : 24.19 MB
Format : PDF, Mobi
Download : 695
Read : 1019

This volume presents information on both the basic and clinical aspects of sphingolipid-metabolizing enzymes in various cancers. The volume also includes discussions of the innovative techniques and approaches for quantitative analysis and imaging that could significantly impact the general understanding of this topic, and the potential benefit of targeting sphingolipid enzymes to develop novel cancer therapeutics. As well, the volume includes a critical examination of the specific pathways and pathobiologies associated with the altered regulation of sphingolipid metabolism as a contributor to the development and/or maintenance of pathological conditions such as cancer.
Category: Medical

Cell Death Signaling In Cancer Biology And Treatment

Author : Daniel Johnson
ISBN : 9781461458470
Genre : Science
File Size : 34.9 MB
Format : PDF, Docs
Download : 930
Read : 668

A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.
Category: Science

Bioactive Sphingolipids In Cancer Biology And Therapy

Author : Yusuf A. Hannun
ISBN : 9783319207506
Genre : Medical
File Size : 82.59 MB
Format : PDF, Mobi
Download : 895
Read : 525

This volume presents information on both the basic and clinical aspects of sphingolipid-metabolizing enzymes in various cancers. The volume also includes discussions of the innovative techniques and approaches for quantitative analysis and imaging that could significantly impact the general understanding of this topic, and the potential benefit of targeting sphingolipid enzymes to develop novel cancer therapeutics. As well, the volume includes a critical examination of the specific pathways and pathobiologies associated with the altered regulation of sphingolipid metabolism as a contributor to the development and/or maintenance of pathological conditions such as cancer.
Category: Medical

Sphingolipids In Cancer

Author :
ISBN : 9780128142240
Genre : Medical
File Size : 45.40 MB
Format : PDF, Kindle
Download : 600
Read : 1310

Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of ceramide-dependent cancer cell death, Sphingolipids as regulators of autophagy and endocytic trafficking, The role and function of sphingomyelin biosynthesis in the development of cancer, Neutral sphingomyelinases in cancer: Friend or foe?, Sphingolipid rendezvous at the crossroad of NAFLD and senescence, Ceramide signaling and p53 pathways, Sphingolipid regulation of RNA Biology in cancer phenotypes, The role of ceramide-1-phosphate in tumor cell survival and dissemination, and more. Provides information on cancer research, with this release focusing on sphingolipids Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike
Category: Medical

Sphingolipid Biology

Author : Y. Hirabayashi
ISBN : 4431342001
Genre : Science
File Size : 63.89 MB
Format : PDF, Docs
Download : 533
Read : 548

Sphingolipids are fundamental to the structures of cell membranes, lipoproteins, and the stratum cornea of the skin. Many complex sphingolipids, as well as simpler sphingoid bases and derivatives, are highly bioactive as extra- and intracellular regulators of growth, differentiation, migration, survival, senescence, and numerous cellular responses to stress. This book reviews exciting new developments in sphingolipid biology/sphingolipidology that challenge our understanding of how multicellular organisms grow, develop, function, age, and die.
Category: Science

Lipidomics Of Stem Cells

Author : Alice Pébay
ISBN : 9783319493435
Genre : Science
File Size : 77.68 MB
Format : PDF, ePub, Mobi
Download : 130
Read : 540

This book combines the current knowledge on the role of lipids in stem cell pluripotency and differentiation. It showcases various approaches to the study of lipids and focuses on various types of stem cells and specific lipids driving maintenance or differentiation. The volume includes chapters reviewing roles of specific lipids in pluripotency, neurogenesis and exocytosis as well as in cancer stem cells. Examples of different classes of lipids—such as sphingolipids, lysophospholipids, cannabinoids and neutral lipids—are described and illustrate the vast biological effects of this class of molecules. The international contributors are all recognized experts in their respective fields. Covering the various aspects of the topic, Lipidomics of Stem Cells provides an up-to-date snapshot—unique among the literature—of where the lipid world is in terms of understanding the roles of lipids in stem cell biology. It provides an essential reference for stem cell biologists, lipid biologists, development biologists, students, academics and clinicians in related areas.
Category: Science

Amides Advances In Research And Application 2013 Edition

Author :
ISBN : 9781481672542
Genre : Science
File Size : 79.11 MB
Format : PDF, ePub
Download : 514
Read : 869

Amides—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Ceramides. The editors have built Amides—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ceramides in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Amides—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Category: Science

Sphingolipids In Disease

Author : Erich Gulbins
ISBN : 9783709115114
Genre : Medical
File Size : 74.8 MB
Format : PDF, Docs
Download : 350
Read : 1312

Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease. ​
Category: Medical