THE GUIDE TO INVESTIGATION OF MOUSE PREGNANCY

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The Guide To Investigation Of Mouse Pregnancy

Author : B. Anne Croy
ISBN : 9780123947949
Genre : Science
File Size : 90.8 MB
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The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research. Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications Describes the angiogenic tree the mother’s uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success
Category: Science

Pathology Of The Developing Mouse

Author : Brad Bolon
ISBN : 9781420070095
Genre : Medical
File Size : 40.34 MB
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Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology experimentation in mice but, more importantly, a "how to interpret" resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining the significance of distorted features in some fantastic murine developmental monstrosity. The topics covered in this volume include a full range of subjects encountered when building and wielding a developmental pathology tool kit: baseline anatomic and physiologic traits of developing mice principles of good experimental design and statistical analysis for mouse developmental pathology studies procedures for anatomic pathology examinations, to evaluate structural changes at the macroscopic (gross), microscopic (cells and tissues), and ultrastructural (subcellular) levels, suing conventional autopsy-based or novel non-invasive imaging techniques; methods for clinical pathology testing, to assess the biochemical and cellular composition of tissues and fluids; options and protocols for in situ molecular pathology analysis, to undertake site-specific explorations of the various mechanisms responsible for producing adverse findings (i.e., "lesions") during development; and well-referenced and illustrated guides to the interpretation of anatomic pathology and clinical pathology changes in the animal (embryos, fetuses, neonates, and juveniles) and its support system (placenta).
Category: Medical

Kaufman S Atlas Of Mouse Development Supplement

Author : Richard Baldock
ISBN : 9780128009130
Genre : Science
File Size : 57.67 MB
Format : PDF
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Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. Provides high-resolution images for best visualization of key developmental processes and structures Offers in-depth anatomy and morphological views of organ systems Written descriptions convey developmental origins of the organ systems
Category: Science

Reproduction In Mammals

Author : Virginia Hayssen
ISBN : 9781421423166
Genre : Science
File Size : 23.14 MB
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Newborn mammals can weigh as little as a dime or as much as a motorcycle. Some receive milk for only a few days, whereas others nurse for years. Humans typically have only one baby at a time following nine months of pregnancy, but other mammals have twenty or more young after only a few weeks in utero. What causes this incredible reproductive diversity? In Reproduction in Mammals, Virginia Hayssen and Teri J. Orr present readers with a fascinating examination of the varied reproductive strategies of a broad spectrum of mammals, from marsupials to whales. This unique book’s comprehensive coverage gathers stories from many taxa into a single, cohesive perspective that centers on the reproductive lives of females. The authors shed light on a number of intriguing questions, including • do bigger moms have bigger babies?• do primates have longer pregnancies than other groups?• does habitat influence animals’ reproductive patterns?• do carnivores typically produce larger litters than prey species? The book opens with the authors’ definition of what constitutes a female perspective and an examination of the evolution of reproduction in mammals. It then outlines the typical individual mammalian female: her genetics, anatomy, and physiology. Taking a nuanced approach, Hayssen and Orr describe the female reproductive cycle and explore female mammals’ interactions with males and offspring. Readers will come away from this thought-provoking book with an understanding of not only how reproduction fits into the lives of female mammals but also how biology has affected the enormously diverse reproductive patterns of the phenotypes we observe today.
Category: Science

The Pregnant Body Book

Author : DK
ISBN : 9781405372589
Genre : Medical
File Size : 33.76 MB
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The complete illustrated guide from conception to birth. The Pregnant Body Book is a comprehensive visual guide to every aspect of conception, pregnancy and birth exploring the important changes that take place in a completely revolutionary way. State-of-the-art images, extraordinary photography and accessible text track each stage of both the mother and baby's development from fertilisation to birth week-by-week. This unprecedented guide covers everything you could possibly want to know from the science behind sex and conception to the intricacies of genetics and includes a detailed look at the anatomy and physiology of both the male and female reproductive systems and the groundbreaking medical advances that define the 21st-century understanding of pregnancy. The Pregnant Body Book is the first of its kind and an ideal reference for prospective parents, as well as both medical and midwifery students.
Category: Medical

Having Faith

Author : Sandra Steingraber
ISBN : 9780738216621
Genre : Health & Fitness
File Size : 27.76 MB
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A brilliant writer, first-time mother, and respected biologist, Sandra Steingraber tells the month-by-month story of her own pregnancy, weaving in the new knowledge of embryology, the intricate development of organs, the emerging architecture of the brain, and the transformation of the mother's body to nourish and protect the new life. At the same time, she shows all the hazards that we are now allowing to threaten each precious stage of development, including the breast-feeding relationship between mothers and their newborns. In the eyes of an ecologist, the mother's body is the first environment, the mediator between the toxins in our food, water, and air and her unborn child.Never before has the metamorphosis of a few cells into a baby seemed so astonishingly vivid, and never before has the threat of environmental pollution to conception, pregnancy, and even to the safety of breast milk been revealed with such clarity and urgency. In Having Faith, poetry and science combine in a passionate call to action.A Merloyd Lawrence Book
Category: Health & Fitness

Animal Models In Eye Research

Author :
ISBN : 0080921035
Genre : Science
File Size : 28.54 MB
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The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. * Presents information on the major animal models used in eye research including invertebrates and vertebrates * Provides researchers with information needed to choose between model organisms * Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery
Category: Science

Regulation Of Implantation And Establishment Of Pregnancy In Mammals

Author : Rodney D. Geisert
ISBN : 9783319158563
Genre : Medical
File Size : 61.55 MB
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Over the past few decades technological advances in transcriptomics, proteomics, metabolomics, and glycomics along with the ability to selectively knockout genes of interest has greatly advanced our understanding of maternal-conceptus interactions that are essential for the establishment and maintenance of a successful pregnancy. This knowledge provides a foundation from which to build research endeavors to help resolve infertility, embryonic loss and recurrent abortion in humans, captive wild animals and important farm species. The present volume on “Regulation of Implantation and Establishment of Pregnancy in Mammals” brings together current reviews from leading experts to address the diversity of mechanisms by which species establish and maintain pregnancy. Implantation in rodents, dogs, pigs, cattle, sheep, horses, primates, humans and embryonic diapause in wild species are discussed. Reviews will provide current knowledge on the role of endometrial steroid receptors, adhesion factors, cytokines, interferons, steroids, prostaglandins, growth factors and immune cells involved with regulation of conceptus development.
Category: Medical

Manipulating The Mouse Embryo

Author : Brigid Hogan
ISBN : 0879693843
Genre : Science
File Size : 42.67 MB
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A comprehensive source of technical guidance for experienced investigators and essential resource for newcomers to mammalian genetics and embryology. This edition (1st ed., 1986) is revised and expanded to incorporate improvements to existing methods as well as new technologies. It contains new sect
Category: Science