THE BIOLOGY OF CANCER 2ND EDITION

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The Biology Of Cancer Second Edition

Author : Robert Weinberg
ISBN : 9781317963462
Genre : Science
File Size : 90.22 MB
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Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world. The Biology of Cancer is a textbook for students studying the molecular and cellular bases of cancer at the undergraduate, graduate, and medical school levels. The principles of cancer biology are presented in an organized, cogent, and in-depth manner. The clarity of writing, supported by an extensive full-color art program and numerous pedagogical features, makes the book accessible and engaging. The information unfolds through the presentation of key experiments that give readers a sense of discovery and provide insights into the conceptual foundation underlying modern cancer biology.
Category: Science

Molecular Biology Of Cancer

Author : Lauren Pecorino
ISBN : 0199211485
Genre : Medical
File Size : 55.40 MB
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The second edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics gives a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal components of the regulatory machinery through which cell division is controlled, and explains how the failure of these components can lead to the onset of cancer. Uniquely, within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies. Written with the student learner in mind, the book features a variety of learning features to help students engage with, and master, the concepts presented. The emphasis is not on exhaustive coverage of the field, but on acquiring a solid understanding of the essentials of the subject - and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit. The Molecular Biology of Cancer is an invaluable resource for any student wishing to gain an insight into the molecular basis of the disease, and possible solutions for its effective control.
Category: Medical

Genes And The Biology Of Cancer

Author : Harold Varmus
ISBN : 0716750376
Genre : Medical
File Size : 68.75 MB
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Discusses advances in cancer research and shows how research into the causes of cancer have led to a greater understanding of the normal biological functioning of cells
Category: Medical

The Molecular Biology Of Cancer

Author : Stella Pelengaris
ISBN : 9781118430859
Genre : Science
File Size : 38.91 MB
Format : PDF
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The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. “Bench to Bedside”: A key strength of this book that sets it apart from general cancer biology references is the interweaving of all aspects of cancer biology from the causes, development and diagnosis through to the treatment and care of cancer patients – essential for providing a broader view of cancer and its impact. The highly readable presentation of a complex field, written by an international panel of researchers, specialists and practitioners, would provide an excellent text for graduate and undergraduate courses in the biology of cancer, medical students and qualified practitioners in the field preparing for higher exams, and for researchers and teachers in the field. For the teaching of cancer biology, special features have been included to facilitate this use: bullet points at the beginning of each chapter explaining key concepts and controversial areas; each chapter builds on concepts learned in previous chapters, with a list of key outstanding questions remaining in the field, suggestions for further reading, and questions for student review. All chapters contain text boxes that provide additional and relevant information. Key highlights are listed below: An overview of the cancer cell and important new concepts. Selected human cancers: lung, breast, colorectal, prostate, renal, skin, cervix, and hematological malignancies. Key cellular processes in cancer biology including (a) traditionally important areas such as cell cycle control, growth regulation, oncogenes and tumour suppressors apoptosis, as well as (b) more highly topical areas of apoptosis, telomeres, DNA damage and repair, cell adhesion, angiogenesis, immunity, epigenetics, and the proteasome. Clinical oncology: In-depth coverage of important concepts such as screening, risk of cancer and prevention, diagnoses, managing cancer patients from start to palliative care and end-of-life pathways. Chapters highlighting the direct links between cancer research and clinical applications. New coverage on how cancer drugs are actually used in specific cancer patients, and how therapies are developed and tested. Systems Biology and cutting edge research areas covered such as RNA interference (RNAi). Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. Quotations have been used in each chapter to introduce basic concepts in an entertaining way. Supported by a dedicated website at www.blackwellpublishing.com/pelengaris We should list the great reviews we got for first edition which are on the back of the 2nd edition: “A capturing, comprehensive, clearly written and absolutely accurate introduction into cancer biology…..This book deserves great praise for the readable presentation of this complex field….the true synthesis of bench and bedside approaches is marvelously achieved.” Christian Schmidt, Molecular Cell “Chapters address the issues of cancer diagnosis, treatment, and patient care and set the book apart from general molecular biology references….This book is applicable to both graduate and undergraduate students, and in the context of a research laboratory, this book would be an excellent resource as a reference guide for scientists at all levels.” V.Emuss, Institute of Cancer Research, London. Also, from the first edition: “Pelengaris, Khan, and the contributing authors are to be applauded. The Molecular Biology of Cancer is a comprehensive and readable presentation of the many faces of cancer from molecular mechanisms to clinical therapies and diagnostics. This book will be welcomed by neophyte students, established scientists in other fields, and curious physicians.” -Dean Felsher, Stanford University
Category: Science

The Biology Of Cancer

Author : Janice Ann Gabriel
ISBN : 0470518170
Genre : Medical
File Size : 35.87 MB
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Advances in research and the treatment of cancer mean that more patients and their carers are asking healthcare professionals about the latest treatments and how they may be of benefit. It is essential that staff working with cancer patients understand fully how these new treatments work in order to disseminate timely and appropriate information to patients. The application of biology to the delivery of cancer care is playing an ever-increasing role in the management of these diseases. The Biology of Cancer: Second Edition provides details of the most recent developments in cancer care and is divided into three sections: Understanding Cancer – examines predisposing factors to developing cancer, diagnosis and its implications on the individual and society. The Science of Cancer – a closer look at the cell, genetics, the immune system, tumour markers and monoclonal antibodies. Research and Treatment – exploring translational oncology, applying research methodology to cancer research and research ethics relating to cancer. This fully updated edition also looks at evidence-based research that can be translated directly to patient care and gives details recent developments. Written by experienced, practicing healthcare professionals, The Biology of Cancer: Second Edition can easily be applied to patient care. It is an informative text for students, newly qualified nurses and practising oncology/palliative care nurses.
Category: Medical

One Renegade Cell

Author : Robert A. Weinberg
ISBN : 0786724013
Genre : Science
File Size : 73.48 MB
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Cancer research has reached a major turning point, and no one is better qualified to explain the past two deacades' dramatic leaps forward in understanding this disease than world-renowned molecular biologist Robert Weinberg, director of the Oncology Research Laboratory at the Whitehead Institute in Cambridge, Massachusetts. In One Renegade Cell, Weinberg presents a state-of-the-art account of how cancer begins and how, one day, it will be cured.
Category: Science

Principles Of Cancer Biology

Author : Lewis J. Kleinsmith
ISBN : UOM:39015063094331
Genre : Health & Fitness
File Size : 82.88 MB
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Principles of Cancer Biology,is an engaging book focused on providing readers with a “big picture” view of cancer. Author Lewis Kleinsmith has written an instructional text focusing on key concepts for a general audience. Each chapter contains a list of suggested readings that expand the detail as needed. The text also emphasizes the scientific evidence that underlies cancer biology, and teaches readers to think critically about this evidence- as there are constantly new “breakthroughs” and reports in this field. For readers who need the review, there are brief reviews of several topics related to DNA replication and repair, cell division, cell signaling, and inheritance patterns in chapters where these subjects are relevant. By including these reviews, the text is both accessible and engaging to a broad audience of readers who are studying cancer biology for the first time, as well as an interested general audience.What Is Cancer, Profile of a Cancer Cell, How Cancers Spread, Identifying the Causes of Cancer, Chemicals and Cancer, Radiation and Cancer, Infectious Agents and Cancer, Heredity and Cancer, Oncogenes, Tumor Suppressor Genes and Cancer Overview, Cancer Screening, Diagnosis, and Treatment, Preventing Cancer, Main Types of Cancer, Human Carcinogens.For all readers interested in the big picture view of cancer.
Category: Health & Fitness

Cancer Biology

Author : Raymond W. Ruddon
ISBN : UOM:39015012531342
Genre : Medical
File Size : 31.48 MB
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Substantially expanded in its second edition,Cancer Biologyincorporates the important recent advances in research on the cellular and molecular biology of cancer and provides a comprehensive discussion of the mechanisms of carcinogenesis. The text describes the malignant transformation of cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of diseased cells into the host organism. In addition to a new chapter on the biology of tumor metastasis, there are three new chapters on cancer causation, dealing with the chemical and physical carcinogens; viruses and oncogenes; and chromosomal abnormalities and gene depression. Updated material on growth factors and their receptors, differentiation, and the cell matrix is also presented, and the pathophysiology of cancer as a clinical disease is discussed.Praise for the first edition:"Highly recommended for readers who wish to spend several hours with a well-written, well-selected, effectively illustrated, and well-integrated overview of the sciences that join to make up the field of tumor biology."--The New England Journal of Medicine."I can think of no better introduction for a graduate student to contemporary cancer research, especially at the cellular level."--G.A. Currie inThe Times Higher Education Supplement. "Ruddon provides a status report in a rapidly moving field. The material is will presented and current, and includes excellent essays on differentiation, phenotype expression, genetic mutation, and tumor growth.... A welcome contrast to multiauthor oncologic behemoths that are too heavy to carry and too expensive to acquire."--Journal of the American Medical Association
Category: Medical

Introduction To Cancer Biology

Author : Robin Hesketh
ISBN : 9781107013988
Genre : Medical
File Size : 34.7 MB
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A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.
Category: Medical

Cancer Drug Design And Discovery

Author : Stephen Neidle
ISBN : 9780123972286
Genre : Medical
File Size : 63.10 MB
Format : PDF
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Cancer Drug Design and Discovery, Second Edition is an important reference on the underlying principles for the design and subsequent development of new anticancer small molecule agents. New chapters have been added to this edition on areas of particular interest and therapeutic promise, including cancer genomics and personalized medicine, DNA-targeted agents and more. This book includes several sections on the basic and applied science of cancer drug discovery and features those drugs that are now approved for human use and are in the marketplace, as well as those that are still under development. By highlighting some of the general principles involved in taking molecules through basic science to clinical development, this book offers a complete and authoritative reference on the design and discovery of anticancer drugs for translational scientists and clinicians involved in cancer research. Provides a clinical perspective on the development of new molecularly targeted anticancer agents with the latest and most promising chemotherapeutic approaches Offers a broad view of where the field is going, what tools drug discovery is using to produce new agents and how they are evaluated in the laboratory and clinic Features 6 new chapters devoted to advances in technology and successful anticancer therapies, such as cancer genomics and personalized medicine, DNA-targeted agents, B-Raf inhibitors and more Each chapter includes extensive references to the primary and review literature, as well as to relevant web-based sources
Category: Medical