THE BIOLOGY OF CANCER 2ND EDITION

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The Biology Of Cancer Second Edition

Author : Robert Weinberg
ISBN : 9781317963462
Genre : Science
File Size : 41.77 MB
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Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world. The Biology of Cancer is a textbook for students studying the molecular and cellular bases of cancer at the undergraduate, graduate, and medical school levels. The principles of cancer biology are presented in an organized, cogent, and in-depth manner. The clarity of writing, supported by an extensive full-color art program and numerous pedagogical features, makes the book accessible and engaging. The information unfolds through the presentation of key experiments that give readers a sense of discovery and provide insights into the conceptual foundation underlying modern cancer biology.
Category: Science

Genes And The Biology Of Cancer

Author : Harold Varmus
ISBN : 0716750376
Genre : Medical
File Size : 38.70 MB
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Discusses advances in cancer research and shows how research into the causes of cancer have led to a greater understanding of the normal biological functioning of cells
Category: Medical

Molecular Biology Of Cancer

Author : Lauren Pecorino
ISBN : 0199211485
Genre : Medical
File Size : 64.16 MB
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The second edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics gives a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal components of the regulatory machinery through which cell division is controlled, and explains how the failure of these components can lead to the onset of cancer. Uniquely, within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies. Written with the student learner in mind, the book features a variety of learning features to help students engage with, and master, the concepts presented. The emphasis is not on exhaustive coverage of the field, but on acquiring a solid understanding of the essentials of the subject - and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit. The Molecular Biology of Cancer is an invaluable resource for any student wishing to gain an insight into the molecular basis of the disease, and possible solutions for its effective control.
Category: Medical

The Molecular Biology Of Cancer

Author : Stella Pelengaris
ISBN : 9781118430859
Genre : Science
File Size : 73.66 MB
Format : PDF
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The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. “Bench to Bedside”: A key strength of this book that sets it apart from general cancer biology references is the interweaving of all aspects of cancer biology from the causes, development and diagnosis through to the treatment and care of cancer patients – essential for providing a broader view of cancer and its impact. The highly readable presentation of a complex field, written by an international panel of researchers, specialists and practitioners, would provide an excellent text for graduate and undergraduate courses in the biology of cancer, medical students and qualified practitioners in the field preparing for higher exams, and for researchers and teachers in the field. For the teaching of cancer biology, special features have been included to facilitate this use: bullet points at the beginning of each chapter explaining key concepts and controversial areas; each chapter builds on concepts learned in previous chapters, with a list of key outstanding questions remaining in the field, suggestions for further reading, and questions for student review. All chapters contain text boxes that provide additional and relevant information. Key highlights are listed below: An overview of the cancer cell and important new concepts. Selected human cancers: lung, breast, colorectal, prostate, renal, skin, cervix, and hematological malignancies. Key cellular processes in cancer biology including (a) traditionally important areas such as cell cycle control, growth regulation, oncogenes and tumour suppressors apoptosis, as well as (b) more highly topical areas of apoptosis, telomeres, DNA damage and repair, cell adhesion, angiogenesis, immunity, epigenetics, and the proteasome. Clinical oncology: In-depth coverage of important concepts such as screening, risk of cancer and prevention, diagnoses, managing cancer patients from start to palliative care and end-of-life pathways. Chapters highlighting the direct links between cancer research and clinical applications. New coverage on how cancer drugs are actually used in specific cancer patients, and how therapies are developed and tested. Systems Biology and cutting edge research areas covered such as RNA interference (RNAi). Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. Quotations have been used in each chapter to introduce basic concepts in an entertaining way. Supported by a dedicated website at www.blackwellpublishing.com/pelengaris We should list the great reviews we got for first edition which are on the back of the 2nd edition: “A capturing, comprehensive, clearly written and absolutely accurate introduction into cancer biology…..This book deserves great praise for the readable presentation of this complex field….the true synthesis of bench and bedside approaches is marvelously achieved.” Christian Schmidt, Molecular Cell “Chapters address the issues of cancer diagnosis, treatment, and patient care and set the book apart from general molecular biology references….This book is applicable to both graduate and undergraduate students, and in the context of a research laboratory, this book would be an excellent resource as a reference guide for scientists at all levels.” V.Emuss, Institute of Cancer Research, London. Also, from the first edition: “Pelengaris, Khan, and the contributing authors are to be applauded. The Molecular Biology of Cancer is a comprehensive and readable presentation of the many faces of cancer from molecular mechanisms to clinical therapies and diagnostics. This book will be welcomed by neophyte students, established scientists in other fields, and curious physicians.” -Dean Felsher, Stanford University
Category: Science

One Renegade Cell

Author : Robert A. Weinberg
ISBN : 0786724013
Genre : Science
File Size : 67.46 MB
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Cancer research has reached a major turning point, and no one is better qualified to explain the past two deacades' dramatic leaps forward in understanding this disease than world-renowned molecular biologist Robert Weinberg, director of the Oncology Research Laboratory at the Whitehead Institute in Cambridge, Massachusetts. In One Renegade Cell, Weinberg presents a state-of-the-art account of how cancer begins and how, one day, it will be cured.
Category: Science

Introduction To Cancer Biology

Author : Robin Hesketh
ISBN : 9781107013988
Genre : Medical
File Size : 89.17 MB
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A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.
Category: Medical

Principles Of Cancer Biology

Author : Lewis J. Kleinsmith
ISBN : UOM:39015063094331
Genre : Health & Fitness
File Size : 39.12 MB
Format : PDF
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Principles of Cancer Biology,is an engaging book focused on providing readers with a “big picture” view of cancer. Author Lewis Kleinsmith has written an instructional text focusing on key concepts for a general audience. Each chapter contains a list of suggested readings that expand the detail as needed. The text also emphasizes the scientific evidence that underlies cancer biology, and teaches readers to think critically about this evidence- as there are constantly new “breakthroughs” and reports in this field. For readers who need the review, there are brief reviews of several topics related to DNA replication and repair, cell division, cell signaling, and inheritance patterns in chapters where these subjects are relevant. By including these reviews, the text is both accessible and engaging to a broad audience of readers who are studying cancer biology for the first time, as well as an interested general audience.What Is Cancer, Profile of a Cancer Cell, How Cancers Spread, Identifying the Causes of Cancer, Chemicals and Cancer, Radiation and Cancer, Infectious Agents and Cancer, Heredity and Cancer, Oncogenes, Tumor Suppressor Genes and Cancer Overview, Cancer Screening, Diagnosis, and Treatment, Preventing Cancer, Main Types of Cancer, Human Carcinogens.For all readers interested in the big picture view of cancer.
Category: Health & Fitness

The Molecular Basis Of Cancer

Author : John Mendelsohn
ISBN : 0721672914
Genre : Medical
File Size : 47.37 MB
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The state-of-the-art 2nd Edition of this acclaimed reference explains the principles that form the scientific basis for our understanding of malignant transformation and the pathogenesis and treatment of cancer. Readers will find a broad update on the scientific principles of new diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating the latest advances and newest research, this text also gives thorough descriptions of everything from the basic mechanisms of malignant cells and molecular abnormalities in common cancers to new approaches for cancer therapy. Each chapter discusses the clinical implications for treatment. Numerous examples of the latest clinical interventions help readers understand and assess the products of the biotechnology revolution. IMPORTANT new topics, including chemo-prevention, programmed cell death (apoptosis), genetic counselling, tumour-specific vaccines, genetic abnormalities in the origin and progression of cancer, monoclonal antibody therapy, and molecular predictors of prognosis and response to treatment NEW and revised chapters, covering new basic science knowledge, new approaches to treatment and keeping all information on the cutting-edge of the specialty ABUNDANT illustrations, most of them new, to clarify and explain difficult concepts.
Category: Medical

A Practical Guide To Cancer Systems Biology

Author : Juan Hsueh-fen
ISBN : 9789813229167
Genre : Medical
File Size : 73.96 MB
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Systems biology combines computational and experimental approaches to analyze complex biological systems and focuses on understanding functional activities from a systems-wide perspective. It provides an iterative process of experimental measurements, data analysis, and computational simulation to model biological behavior. This book provides explained protocols for high-throughput experiments and computational analysis procedures central to cancer systems biology research and education. Readers will learn how to generate and analyze high-throughput data, therapeutic target protein structure modeling and docking simulation for drug discovery. This is the first practical guide for students and scientists who wish to become systems biologists or utilize the approach for cancer research. Contents: Introduction to Cancer Systems Biology (Hsueh-Fen Juan and Hsuan-Cheng Huang)Transcriptome Analysis: Library Construction (Hsin-Yi Chang and Hsueh-Fen Juan)Quantitative Proteome: The Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) (Yi-Hsuan Wu and Hsueh-Fen Juan)Phosphoproteome: Sample Preparation (Chia-Wei Hu and Hsueh-Fen Juan)Transcriptomic Data Analysis: RNA-Seq Analysis Using Galaxy (Chia-Lang Hsu and Chantal Hoi Yin Cheung)Proteomic Data Analysis: Functional Enrichment (Hsin-Yi Chang and Hsueh-Fen Juan)Phosphorylation Data Analysis (Chia-Lang Hsu and Wei-Hsuan Wang)Pathway and Network Analysis (Chen-Tsung Huang and Hsueh-Fen Juan)Dynamic Modeling (Yu-Chao Wang)Protein Structure Modeling (Chia-Hsien Lee and Hsueh-Fen Juan)Docking Simulation (Chia-Hsien Lee and Hsueh-Fen Juan) Readership: Graduate students and researchers entering the cancer systems biology field. Keywords: Systems Biology;Transcriptomics;Proteomics;Network Biology;Dynamic Modeling;Protein Structure Modeling;Docking Simulation;BioinformaticsReview: Key Features: Written by two active researchers in the fieldCovers both experimental and computational areas in cancer systems biologyStep-by-step instructions help beginners who are interested in creating biological data and analyzing the data by themselvesReaders will gain the skills to generate and analyze omics data and discover potential therapeutic targets and drug candidates
Category: Medical

The Biology Of Cancer

Author : Janice Ann Gabriel
ISBN : 0470518170
Genre : Medical
File Size : 57.76 MB
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Advances in research and the treatment of cancer mean that more patients and their carers are asking healthcare professionals about the latest treatments and how they may be of benefit. It is essential that staff working with cancer patients understand fully how these new treatments work in order to disseminate timely and appropriate information to patients. The application of biology to the delivery of cancer care is playing an ever-increasing role in the management of these diseases. The Biology of Cancer: Second Edition provides details of the most recent developments in cancer care and is divided into three sections: Understanding Cancer – examines predisposing factors to developing cancer, diagnosis and its implications on the individual and society. The Science of Cancer – a closer look at the cell, genetics, the immune system, tumour markers and monoclonal antibodies. Research and Treatment – exploring translational oncology, applying research methodology to cancer research and research ethics relating to cancer. This fully updated edition also looks at evidence-based research that can be translated directly to patient care and gives details recent developments. Written by experienced, practicing healthcare professionals, The Biology of Cancer: Second Edition can easily be applied to patient care. It is an informative text for students, newly qualified nurses and practising oncology/palliative care nurses.
Category: Medical