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Synthetic Vaccines

Author : Cornelius Melief
ISBN : 9780123965486
Genre : Medical
File Size : 57.99 MB
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Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on synthetic vaccines. Contributions from leading authorities Informs and updates on all the latest developments in the field
Category: Medical


Author : Ronald W. Ellis
ISBN : UOM:39015028474982
Genre : Medical
File Size : 90.96 MB
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Evolving technologies and strategies for researching vaccines have led to new approaches in developing vaccines for many diseases which could not be prevented until now. This volume presents vaccine research and technology which has been collected from many scientists in the field.
Category: Medical

Advances In Immunology

Author :
ISBN : 0080578217
Genre : Medical
File Size : 64.92 MB
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Advances in Immunology
Category: Medical

Immunopotentiators In Modern Vaccines

Author : Virgil Schijns
ISBN : 9780128040959
Genre : Science
File Size : 82.20 MB
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Immunopotentiators in Modern Vaccines, Second Edition, provides in-depth insights and overviews of the most successful adjuvants, those that have been included in licensed products, also covering the most promising technologies that have emerged in recent years. In contrast to existing books on the subject, the chapters here provide summaries of key data on the mechanisms of action of the individual vaccine adjuvants. In addition, the book covers key aspects of how the technologies might be further developed and what might be their limitations, while also giving an overview of what made the most advanced adjuvant technologies successful. Provides contributions from leading international authorities in the field Features immunopotentiators classified by function, with well-illustrated, informative figures presenting the interaction between the immunopotentiators and the host immune system Lists advantages and potential hurdles for achieving a practical application for each specific immunopotentiator Offers US FDA perspectives which highlight how future adjuvants will be approved for new generation vaccines
Category: Science

The Vaccine Book

Author : Barry R. Bloom
ISBN : 9780128054000
Genre : Science
File Size : 89.73 MB
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The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy
Category: Science

Recent Advances In Immunology

Author : Asuman U. Muftuoglu
ISBN : 9781468446494
Genre : Medical
File Size : 29.80 MB
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The aim of this publication is to present the up-to-date views of the many eminent immunologists who contributed to the scientific program of the 5th European Immunology Meeting held in Istanbul in June 1982. Recent Advances in Immunology is intended for immunol ogists both in the basic sciences and in clinical medicine. It provides under one cover an assemblage of information about funda mental problems in immunology and clinical applications. The book opens with Prof. E. A. Kabat's review of the problems in understanding the structural basis of antibody complementarity. The succeeding four papers deal with the role of macrophages in the various stages of immune phenomena. The first of the two articles on T cells reports a product necessary for suppressor activity and the second describes an analysis of precursors of cytotoxic T lym phocytes. The articles dealing with immunogenetics start with the description of new loci in HLA by Prof. J. J. van Rood and co-workers followed by a paper describing the molecular cloning of H-2 class I genes. Prof. P. J. Lachmann begins the discussion on the genetics of the complement system. There are three stimulating articles on the chemistry and genetics of the complement components and their asso ciations with disease. After a review of artificial antigens and synthetic vaccines, papers on immunomodulation describe strategies for improving immunogenicity, immunomodulation in tumor systems and by xenobiotics.
Category: Medical

Carbohydrate Based Vaccines And Immunotherapies

Author : Zhongwu Guo
ISBN : 9780470473276
Genre : Science
File Size : 30.18 MB
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The fundamental science and the latest developments in carbohydrate-based vaccines The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments. With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances. Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include: Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi Using adjuvants to improve immunogenicity and/or immunological properties of vaccines Choosing and designing proper adjuvants for specific targets Abnormal carbohydrates expressed by tumors Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy Clinical trials results for synthetic cancer vaccines Glycoengineering of cell surface carborhydrates and its anticancer applications Using cell surface carbohydrates for disease diagnosis A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.
Category: Science

Synthetic Peptides As Antigens

Author : S. Muller
ISBN : 008085897X
Genre : Medical
File Size : 49.64 MB
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This newest edition to the Laboratory Techniques Series gives current state of the art use of synthetic peptides in molecular biology and practical protocols on how to conjugate peptides, immunize animals with peptides and monitor immune responses to peptides in vitro. It gives background information on antigenic specificity, prediction of antigenic sites in proteins and applications of peptides in immunology and virology, as probes in diagnosis and as vaccines. The book also describes antigenicity of proteins and methods to localize antigenic sites as well as methods for predicting epitoxes, and gives detailed protocols for peptide-carrier conjugation, immunization with peptides, and peptide immunoassays. The volume also describes typical use of antipeptide antibodies in molecular and cellular biology as well as the use of peptides in the diagnosis of viral infections and autoimmune diseases, and the use of peptides as potential synthetic vaccines. An excellent edition to an excellent series, available in hardbound and paperback.
Category: Medical

Progress In Immunology V

Author : Yūichi Yamamura
ISBN : MINN:31951000144689W
Genre : Allergy and immunology
File Size : 81.13 MB
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Category: Allergy and immunology

Human Vaccines

Author : Kayvon Modjarrad
ISBN : 9780128025420
Genre : Medical
File Size : 84.58 MB
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Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics—among other disciplines—that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology. Introduces new topics in vaccine immunology in the context vaccine design and production Consolidates the growing body of knowledge on new vaccine technologies that have only emerged in the past 2 – 3 decades Reviews the currently licensed vaccines that have utilized leading-edge technologies and how this has translated into improved efficacy and safety Provides a broad overview of innovative vaccine technologies, including immunological aspects
Category: Medical