REGRESSION METHODS IN BIOSTATISTICS LINEAR LOGISTIC SURVIVAL AND REPEATED MEASURES MODELS 0 STATISTICS FOR BIOLOGY AND HEALTH

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Regression Methods In Biostatistics

Author : Eric Vittinghoff
ISBN : 9781461413530
Genre : Medical
File Size : 54.73 MB
Format : PDF, Mobi
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This new book provides a unified, in-depth, readable introduction to the multipredictor regression methods most widely used in biostatistics: linear models for continuous outcomes, logistic models for binary outcomes, the Cox model for right-censored survival times, repeated-measures models for longitudinal and hierarchical outcomes, and generalized linear models for counts and other outcomes. Treating these topics together takes advantage of all they have in common. The authors point out the many-shared elements in the methods they present for selecting, estimating, checking, and interpreting each of these models. They also show that these regression methods deal with confounding, mediation, and interaction of causal effects in essentially the same way. The examples, analyzed using Stata, are drawn from the biomedical context but generalize to other areas of application. While a first course in statistics is assumed, a chapter reviewing basic statistical methods is included. Some advanced topics are covered but the presentation remains intuitive. A brief introduction to regression analysis of complex surveys and notes for further reading are provided.
Category: Medical

The Evaluation Of Surrogate Endpoints

Author : Geert Molenberghs
ISBN : 0387202773
Genre : Mathematics
File Size : 59.11 MB
Format : PDF
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The identification and use of surrogate endpoints, i.e., measures that can replace or supplement other endpoints in evaluations of experimental treatments or other interventions, is a general strategy that has stimulated both enthusiasm and scepticism. This book offers a balanced account on this controversial topic.
Category: Mathematics

Statistical Modeling For Biomedical Researchers

Author : William D. Dupont
ISBN : 9781139643818
Genre : Medical
File Size : 56.87 MB
Format : PDF
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The second edition of this standard text guides biomedical researchers in the selection and use of advanced statistical methods and the presentation of results to clinical colleagues. It assumes no knowledge of mathematics beyond high school level and is accessible to anyone with an introductory background in statistics. The Stata statistical software package is again used to perform the analyses, this time employing the much improved version 10 with its intuitive point and click as well as character-based commands. Topics covered include linear, logistic and Poisson regression, survival analysis, fixed-effects analysis of variance, and repeated-measure analysis of variance. Restricted cubic splines are used to model non-linear relationships. Each method is introduced in its simplest form and then extended to cover more complex situations. An appendix will help the reader select the most appropriate statistical methods for their data. The text makes extensive use of real data sets available at http://biostat.mc.vanderbilt.edu/dupontwd/wddtext/.
Category: Medical

Textbook Of Cancer Epidemiology

Author : Hans-Olov Adami
ISBN : 9780190676841
Genre : Medical
File Size : 63.6 MB
Format : PDF, Docs
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"Comprehensive and comprehensible, but also encouraging -- informed by the hope and belief that informed its creation." -Cancer Amid sweeping advances in the science and treatment of cancer, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers students and professionals a definitive, systematic resource for understanding the factors affecting all types of human cancer. This fully updated new edition offers an overview of epidemiology's key concepts and methods as they relate to cancer (including the emerging potential of biomarkers) as well as site-specific chapters on individual cancers' natural history, pathology, descriptive epidemiology, and etiology. Taken together, these chapters forge connections between established science and the ongoing evolution of this dynamic field. Crisply and concisely written by an assembly of internationally recognized researchers, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers a superlative introduction to the subject's consensuses and controversies for those embarking on their careers and a ready reference for seasoned professionals.
Category: Medical

Intuitive Biostatistics

Author : Harvey Motulsky
ISBN : 9780199946648
Genre : Medical
File Size : 76.14 MB
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Thoroughly revised and updated, the third edition of Intuitive Biostatistics: A Nonmathematical Guide to Statistical Thinking retains and refines the core perspectives of the previous editions: a focus on how to interpret statistical results rather than on how to analyze data, minimal use of equations, and a detailed review of assumptions and common mistakes. With its engaging and conversational tone, this unique book provides a clear introduction to statistics for undergraduate and graduate students in a wide range of fields and also serves as a statistics refresher for working scientists. It is especially useful for those students in health-science related fields who have no background in biostatistics. NEW TO THIS EDITION * A new chapter on the complexities of probability * A new chapter on meta-analysis * A completely rewritten chapter on statistical traps to avoid * More sections on common mistakes in data analysis * More Q&A sections * New topics and examples * New learning tools (each chapter ends with a summary and a list of statistical terms)
Category: Medical

Primer Of Applied Regression Analysis Of Variance Third Edition

Author : Stanton A. Glantz
ISBN : 9780071822442
Genre : Medical
File Size : 82.91 MB
Format : PDF
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A textbook on the use of advanced statistical methods in healthcare sciences Primer of Applied Regression & Analysis of Variance is a textbook especially created for medical, public health, and social and environmental science students who need applied (not theoretical) training in the use of statistical methods. The book has been acclaimed for its user-friendly style that makes complicated material understandable to readers who do not have an extensive math background. The text is packed with learning aids that include chapter-ending summaries and end-of-chapter problems that quickly assess mastery of the material. Examples from biological and health sciences are included to clarify and illustrate key points. The techniques discussed apply to a wide range of disciplines, including social and behavioral science as well as health and life sciences. Typical courses that would use this text include those that cover multiple linear regression and ANOVA. Four completely new chapters Completely updated software information and examples
Category: Medical

An Introduction To Medical Statistics

Author : Martin Bland
ISBN : 9780191002991
Genre : Medical
File Size : 72.48 MB
Format : PDF, Kindle
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Now in its Fourth Edition, An Introduction to Medical Statistics continues to be a 'must-have' textbook for anyone who needs a clear logical guide to the subject. Written in an easy-to-understand style and packed with real life examples, the text clearly explains the statistical principles used in the medical literature. Taking readers through the common statistical methods seen in published research and guidelines, the text focuses on how to interpret and analyse statistics for clinical practice. Using extracts from real studies, the author illustrates how data can be employed correctly and incorrectly in medical research helping readers to evaluate the statistics they encounter and appropriately implement findings in clinical practice. End of chapter exercises, case studies and multiple choice questions help readers to apply their learning and develop their own interpretative skills. This thoroughly revised edition includes new chapters on meta-analysis, missing data, and survival analysis.
Category: Medical

Generalized Linear Mixed Models

Author : Charles E. McCulloch
ISBN : 0940600544
Genre : Mathematics
File Size : 33.37 MB
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Wiley Series in Probability and Statistics A modern perspective on mixed models The availability of powerful computing methods in recent decades has thrust linear and nonlinear mixed models into the mainstream of statistical application. This volume offers a modern perspective on generalized, linear, and mixed models, presenting a unified and accessible treatment of the newest statistical methods for analyzing correlated, nonnormally distributed data. As a follow-up to Searle's classic, Linear Models, and Variance Components by Searle, Casella, and McCulloch, this new work progresses from the basic one-way classification to generalized linear mixed models. A variety of statistical methods are explained and illustrated, with an emphasis on maximum likelihood and restricted maximum likelihood. An invaluable resource for applied statisticians and industrial practitioners, as well as students interested in the latest results, Generalized, Linear, and Mixed Models features: * A review of the basics of linear models and linear mixed models * Descriptions of models for nonnormal data, including generalized linear and nonlinear models * Analysis and illustration of techniques for a variety of real data sets * Information on the accommodation of longitudinal data using these models * Coverage of the prediction of realized values of random effects * A discussion of the impact of computing issues on mixed models
Category: Mathematics

Spatial Analysis In Epidemiology

Author : Dirk Pfeiffer
ISBN : 9780198509882
Genre : Computers
File Size : 33.64 MB
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Providing a practical, comprehensive and up-to-date overview of the use of spatial statistics in epidemiology, this book examines spatial analytical methods in conjunction with GIS and remotely sensed data to provide insights into the patterns and processes that underlie disease transmission.
Category: Computers

Fundamentals Of Biostatistics

Author : Bernard Rosner
ISBN : 9781133008170
Genre : Science
File Size : 64.4 MB
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Bernard Rosner's FUNDAMENTALS OF BIOSTATISTICS is a practical introduction to the methods, techniques, and computation of statistics with human subjects. It prepares students for their future courses and careers by introducing the statistical methods most often used in medical literature. Rosner minimizes the amount of mathematical formulation (algebra-based) while still giving complete explanations of all the important concepts. As in previous editions, a major strength of this book is that every new concept is developed systematically through completely worked out examples from current medical research problems. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Category: Science