REGENESIS HOW SYNTHETIC BIOLOGY WILL REINVENT NATURE AND OURSELVES

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Regenesis

Author : George M. Church
ISBN : 9780465038657
Genre : Science
File Size : 20.70 MB
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“Bold and provocative… Regenesis tells of recent advances that may soon yield endless supplies of renewable energy, increased longevity and the return of long-extinct species.”—New Scientist In Regenesis, Harvard biologist George Church and science writer Ed Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
Category: Science

Governing Medical Knowledge Commons

Author : Katherine J. Strandburg
ISBN : 9781108298735
Genre : Law
File Size : 32.8 MB
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Governing Medical Knowledge Commons makes three claims: first, evidence matters to innovation policymaking; second, evidence shows that self-governing knowledge commons support effective innovation without prioritizing traditional intellectual property rights; and third, knowledge commons can succeed in the critical fields of medicine and health. The editors' knowledge commons framework adapts Elinor Ostrom's groundbreaking research on natural resource commons to the distinctive attributes of knowledge and information, providing a systematic means for accumulating evidence about how knowledge commons succeed. The editors' previous volume, Governing Knowledge Commons, demonstrated the framework's power through case studies in a diverse range of areas. Governing Medical Knowledge Commons provides fifteen new case studies of knowledge commons in which researchers, medical professionals, and patients generate, improve, and share innovations, offering readers a practical introduction to the knowledge commons framework and a synthesis of conclusions and lessons. The book is also available as Open Access.
Category: Law

Synthetic Biology Handbook

Author : Darren N. Nesbeth
ISBN : 9781466568488
Genre : Medical
File Size : 82.7 MB
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The Synthetic Biology Handbook explains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology, this handbook: Explores the standardisation of classic molecular bioscience approaches Addresses the societal context and potential impacts of synthetic biology Discusses the use of legacy systems as tools for new product development Examines the design and construction of de novo cells and genetic codes Describes computational methods for designing genes and gene networks Thus, the Synthetic Biology Handbook provides an accurate sense of the scope of synthetic biology today. The handbook also affords readers with an opportunity to scrutinize the underlying science and decide for themselves what aspects of synthetic biology are most valuable to their research and practice.
Category: Medical

Synthetic Biology

Author : Joachim Boldt
ISBN : 9783658109882
Genre : Philosophy
File Size : 65.32 MB
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Assessing synthetic biology from a societal and ethical perspective is not only a matter of determining possible harms and benefits of synthetic biology applications. Synthetic biology also incorporates a specific technoscientific understanding of its research agenda and its research objects that has philosophical and ethical implications. This edited volume sets out to explore and evaluate these synthetic biology worldviews and it proposes appropriate governance measures. In addition, legal challenges are discussed.
Category: Philosophy

Humans In Nature

Author : Gregory E. Kaebnick
ISBN : 9780199347230
Genre : Medical
File Size : 22.3 MB
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Contemporary debates over issues as wide-ranging as the protection of wildernesses and endangered species, the spread of genetically modified organisms, the emergence of synthetic biology, and the advance of human enhancement, all of which seem to spin into deeper and more baffling questions with every change in the news cycle, often circle back to the same fundamental question: should there be limits to the human alteration of the natural world? A growing number of people view the human capacity to alter natural states of affairs -- from formerly wild spaces and things around us to crops and livestock to our own human nature -- as cause for moral alarm. That reaction raises a number of perplexing philosophical questions, however: Can we identify "natural" states of affairs at all? Does the idea of being morally concerned about the human relationship to nature make any sense? Should such a concern influence public policy and politics, or should government stay strenuously neutral on such matters? Through a study of moral debates about the environment, agricultural biotechnology, synthetic biology, and human enhancement, Gregory E. Kaebnick, a research scholar at The Hastings Center and editor of the Hastings Center Report, argues that concerns about the human alteration of nature can be legitimate and serious, but also that they are complex, contestable, and of limited political force. Kaebnick defends attempts to identify "natural" states of affairs by disentangling the nature/artifact distinction from metaphysical hoariness. Drawing on David Hume, he also defends moral standards for the human relationship to nature, arguing that they, and moral standards generally, should be understood as grounded in what Hume called the "passions." Yet what counts as "natural" can be delineated only roughly, he concludes, and moral standards for interaction with nature are less a matter of obligation than of ideals. Kaebnick also concludes, drawing on an interpretation of the liberal principle of neutrality, that government may support those standards but must be careful not to enforce them. Thus Kaebnick looks for a middle way on debates that have tended toward polarization. "As differences between nature and artifact become steadily less substantial, problems about preservation run to the core of how people can make sense of themselves, of each other, and of our shared world. Kaebnick's solutions are creative and compelling, theoretically elegant and politically practical. Providing distinctive ways forward, when much academic and policy discussion seems exhausted, his book demands wide attention. In return, it inspires hope." - James Nelson, Michigan State University
Category: Medical

Biocode

Author : Dawn Field
ISBN : 9780191511578
Genre : Science
File Size : 30.33 MB
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The living world runs on genomic software - what Dawn Field and Neil Davies call the 'biocode' - the sum of all DNA on Earth. In Biocode, they tell the story of a new age of scientific discovery: the growing global effort to read and map the biocode, and what that might mean for the future. The structure of DNA was identified in 1953, and the whole human genome was mapped by 2003. Since then the new field of genomics has mushroomed and is now operating on an industrial scale. Genomes can now be sequenced rapidly and increasingly cheaply. The genomes of large numbers of organisms from mammals to microbes, have been mapped. Getting your genome sequenced is becoming affordable for many. You too can check paternity, find out where your ancestors came from, or whether you are at risk of some diseases. Some check out the pedigree of their pets, while others turn genomes into art. A stray hair is enough to crudely reconstruct the face of the owner. From reading to constructing: the first steps to creating artificial life have already been taken. Some may find the rapidity of developments, and the potential for misuse, alarming. But they also open up unprecedented possibilities. The ability to read DNA has changed how we view ourselves and understand our place in nature. From the largest oceans, to the insides of our guts, we are able to explore the biosphere as never before, from the genome up. Sequencing technology has made the invisible world of microbes visible, and biodiversity genomics is revealing whole new worlds within us and without. The findings are transformational: we are all ecosystems now. Already the first efforts at 'barcoding' entire ecological communities and creating 'genomic observatories' have begun. The future, the authors argue, will involve biocoding the entire planet.
Category: Science

Evolving Ourselves

Author : Juan Enriquez
ISBN : 9780698174986
Genre : Science
File Size : 29.57 MB
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“We are the primary drivers of change. We will directly and indirectly determine what lives, what dies, where, and when. We are in a different phase of evolution; the future of life is now in our hands.” Why are rates of conditions like autism, asthma, obesity, and allergies exploding at an unprecedented pace? Why are humans living longer, getting smarter, and having far fewer kids? How might your lifestyle affect your unborn children and grandchildren? How will gene-editing technologies like CRISPR steer the course of human evolution? If Darwin were alive today, how would he explain this new world? Could our progeny eventually become a different species—or several? In Evolving Ourselves, futurist Juan Enriquez and scientist Steve Gullans conduct a sweeping tour of how humans are changing the course of evolution—sometimes intentionally, sometimes not. For example: • Globally, rates of obesity in humans nearly doubled between 1980 and 2014. What’s more, there’s evidence that other species, from pasture-fed horses to lab animals to house cats, are also getting fatter. • As reported by U.S. government agencies, the rate of autism rose by 131 percent from 2001 to 2010, an increase that cannot be attributed simply to increases in diagnosis rates. • Three hundred years ago, almost no one with a serious nut allergy lived long enough to reproduce. Today, despite an environment in which food allergies have increased by 50 percent in just over a decade, 17 million Americans who suffer from food allergies survive, thrive, and pass their genes and behaviors on to the next generation. • In the pre-Twinkie era, early humans had quite healthy mouths. As we began cooking, bathing, and using antibiotics, the bacteria in our bodies changed dramatically and became far less diverse. Today the consequences are evident not only in our teeth but throughout our bodies and minds. Though these harbingers of change are deeply unsettling, the authors argue that we are also in an epoch of tremendous opportunity. New advances in biotechnology help us mitigate the cruel forces of natural selection, from saving prematurely born babies to gene therapies for sickle cell anemia and other conditions. As technology like CRISPR enables us to take control of our genes, we will be able to alter our own species and many others—a good thing, given that our eventual survival will require space travel and colonization, enabled by a fundamental redesign of our bodies. Future humans could become great caretakers of the planet, as well as a more diverse, more resilient, gentler, and more intelligent species—but only if we make the right choices now. Intelligent, provocative, and optimistic, Evolving Ourselves is the ultimate guide to the next phase of life on Earth. From the Hardcover edition.
Category: Science

Future Crimes

Author : Marc Goodman
ISBN : 9781473508460
Genre : True Crime
File Size : 37.37 MB
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* THE NEW YORK TIMES BESTSELLER * Technological advances have benefited our world in immeasurable ways, but there is an ominous flipside. Criminals are often the earliest, and most innovative, adopters of technology and modern times have led to modern crimes. Today's criminals are stealing identities, draining online bank-accounts and wiping out computer servers. It's disturbingly easy to activate baby cam monitors to spy on families, pacemakers can be hacked to deliver a lethal jolt, and thieves are analyzing your social media in order to determine the best time for a home invasion. Meanwhile, 3D printers produce AK-47s, terrorists can download the recipe for the Ebola virus, and drug cartels are building drones. This is just the beginning of the tsunami of technological threats coming our way. In Future Crimes, Marc Goodman rips open his database of hundreds of real cases to give us front-row access to these impending perils. Reading like a sci-fi thriller, but based in startling fact, Goodman raises tough questions about the expanding role of technology in our lives. Future Crimes is a call to action for better security measures worldwide, but most importantly, will empower readers to protect themselves against these looming technological threats - before it's too late.
Category: True Crime

This Idea Is Brilliant

Author : John Brockman
ISBN : 9780062698223
Genre : Science
File Size : 48.86 MB
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Brilliant but overlooked ideas you must know, as revealed by today’s most innovative minds What scientific term or concept ought to be more widely known? That is the question John Brockman, publisher of the acclaimed science salon Edge.org (“The world’s smartest website”—The Guardian), presented to 205 of the world’s most influential thinkers from across the intellectual spectrum—award-winning physicists, economists, psychologists, philosophers, novelists, artists, and more. From the origins of the universe to the order of everyday life, This Idea Is Brilliant takes readers on a tour of the bold, exciting, and underappreciated scientific concepts that will enrich every mind. Pulitzer Prize–winning author of Guns, Germs, and Steel JARED DIAMOND on the lost brilliance of common sense * Oxford evolutionary biologist RICHARD DAWKINS on how The Genetic Book of the Dead could reconstruct ecological history * philosopher REBECCA NEWBERGER GOLDSTEIN on how to extend our grasp of reality beyond what we can see and touch * author of Seven Brief Lessons on Physics CARLO ROVELLI on the interconnected fabric of information * Booker Prize–winning novelist IAN McEWAN on the Navier-Stokes equations, which govern everything from weather prediction to aircraft design and blood flow * cosmologist LAWRENCE M. KRAUSS on the hidden blessings of uncertainty * psychologist STEVEN PINKER on the fight against entropy * Nobel Prize–winning economist RICHARD THALER on the visionary power of the “premortem” * Grammy Award–winning musician BRIAN ENO on confirmation bias in the Internet age * advertising guru RORY SUTHERLAND on the world-changing power of sex appeal * Harvard physicist LISA RANDALL on the power of the obvious * Wired founding editor KEVIN KELLY on how to optimize your chances at success * Nobel Prize winner FRANK WILCZEK on the creative potential of complementarity * Pulitzer Prize–winning New York Times reporter JOHN MARKOFF on the synthetic metamaterials that soon will transform industry and technology * euroscientist SAM HARRIS on the lost art of intellectual honesty *Berkeley psychologist ALISON GOPNIK on the role of life history in the human story, and many others.
Category: Science

The Between

Author : Daniel Sweren-Becker
ISBN : 9781250159984
Genre : Young Adult Fiction
File Size : 37.53 MB
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The Between is a digital-only novella that follows the shocking events of The Ones and leads directly into its exciting sequel, The Equals. Having every genetic advantage possible can’t save you when you’re outnumbered 99 to 1. James was one of the lucky ones randomly selected before birth to receive genetic engineering. Known as the Ones, this one percent of the population is healthy, beautiful, and talented . . . and to some, that’s not fair. Mounting fear and jealousy of the Ones’ success led to the creation of the Equality Movement, which quickly gained enough political traction to demote James, his girlfriend Cody, and others like them to second-class citizens. Now James has been captured, separated from everyone he knows, and sent to a detention camp. What he finds there will change him into a new kind of revolutionary—if he survives . . . An Imprint Book Praise for The Ones: "Chilling and frighteningly real, The Ones leads us down a dark rabbit hole of scientific possibilities, fractured morality, and brutal consequences. It forces the question: If perfection becomes a liability, how far are we willing to go in the pursuit of it -- or to stop it?"—Kami Garcia, #1 New York Times bestselling coauthor of Beautiful Creatures and author ofThe Lovely Reckless "Like watching your favorite TV show, The Ones is a thrill ride with a new shock at every turn. You won't believe what happens next, and yet, you should. Because this reality is all too possible." —Melissa de la Cruz, #1 New York Times bestselling author of Isle of the Lost and the forthcoming Something In Between “A gripping and cautionary tale. A thrilling read.” —Brendan Reichs, New York Times-bestselling coauthor of the Virals series. "The basic premise for this captivating tale is much closer to practical concern than many might imagine. It is crucial that we visualize many possible scenarios like this one so that we can humanely respond to (or better yet anticipate) new technologies and the consequences for new babies. We hopefully will not punish the latter for the shortcomings of the former, and books like this will help us all engage with the key issues, technical and moral." —George Church, Professor of Genetics at Harvard Medical School and author of Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves
Category: Young Adult Fiction