PROBABILISTIC TECHNIQUES IN EXPOSURE ASSESSMENT

Download Probabilistic Techniques In Exposure Assessment ebook PDF or Read Online books in PDF, EPUB, and Mobi Format. Click Download or Read Online button to PROBABILISTIC TECHNIQUES IN EXPOSURE ASSESSMENT book pdf for free now.

Probabilistic Techniques In Exposure Assessment

Author : Alison C. Cullen
ISBN : 0306459574
Genre : Medical
File Size : 63.65 MB
Format : PDF, Kindle
Download : 141
Read : 986

At this time when regulatory agencies are accepting and actively encouraging probabilistic approaches and the attribution of overall uncertainty among inputs to support Value of Information analyses, a comprehensive sourcebook on methods for addressing variability and uncertainty in exposure analysis is sorely needed. This need is adroitly met in Probabilistic Techniques in Exposure Assessment. A host of expert contributors provide a straightforward introduction to the practical tools for addressing variability and uncertainty in support of environmental and human health decision making. 151 graphs, plots, charts, and figures supplement a broad range of detailed and practical examples.
Category: Medical

Occupational And Residential Exposure Assessment For Pesticides

Author : Claire Franklin
ISBN : 9780470012208
Genre : Technology & Engineering
File Size : 83.81 MB
Format : PDF
Download : 577
Read : 1197

This timely publication concentrates on the exposure to pesticides by agricultural workers and residential users of pesticides through inhalation and physical contact. The book discusses more recently discovered risks such as pesticides on indoor carpets and includes new trends in data interpretation. Occupational & Residential Exposure Assessment for Pesticides complements the other title on pesticide exposure in the series - Pesticide Residues in Drinking Water, by Hamilton/Crossley and is a must for all professionals in the Pesticide Industry as well as academics.
Category: Technology & Engineering

Uncertainty And Data Quality In Exposure Assessment

Author : World Health Organization
ISBN : 9789241563765
Genre : History
File Size : 25.19 MB
Format : PDF, Docs
Download : 751
Read : 381

Assessment of human exposure to chemicals is a critical input to risk assessment and ultimately to decisions about control of chemicals. This two-part publication aims to improve the quality of information available to decision-makers and its communication. Part one sets out ten principles for characterizing and communicating uncertainty in exposure assessment. A tiered approach to the evaluation of uncertainties using both qualitative (simple) and quantitative (more complex) methods is described. Different sources of uncertainty are identified and guidance is provided on selecting the appropriate approach to uncertainty analysis as dictated by the objectives of the assessment and information needs of decision-makers and stakeholders. Part two addresses the quality of data used in exposure assessment and sets out four basic hallmarks of data quality - appropriateness accuracy integrity and transparency. These hallmarks provides a common vocabulary and set of qualitative criteria for use in the design evaluation and use of exposure assessments to support decisions. This publication is intended exposure assessors risk assessors and decision-makers.
Category: History

Principles Of Characterizing And Applying Human Exposure Models

Author : World Health Organization
ISBN : 9789241563116
Genre : Medical
File Size : 87.76 MB
Format : PDF, Docs
Download : 465
Read : 1162

The objective of this manual is to provide guidance to risk assessors on the use of quantitative toxicokinetic and toxicodynamic data to address interspecies and interindividual differences in dose/concentration-response assessment. Section 1 focuses on the relevance of this guidance in the context of the broader risk assessment paradigm and other initiatives of the International Programme on Chemical Safety (IPCS) project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals. Technical background material is presented in section 2, followed by generic guidance for the development of chemical-specific adjustment factors in section 3 and accompanying summary figures. Illustrative case-studies are included in an Appendix, and a glossary of terms is also provided.
Category: Medical

Risk Assessment Methods

Author : V.T. Covello
ISBN : 9781489912169
Genre : Technology & Engineering
File Size : 50.23 MB
Format : PDF
Download : 769
Read : 839

Much has already been written about risk assessment. Epidemiologists write books on how risk assessment is used to explore the factors that influence the distribution of disease in populations of people. Toxicologists write books on how risk assess ment involves exposing animals to risk agents and concluding from the results what risks people might experience if similarly exposed. Engineers write books on how risk assessment is utilized to estimate the risks of constructing a new facility such as a nuclear power plant. Statisticians write books on how risk assessment may be used to analyze mortality or accident data to determine risks. There are already many books on risk assessment-the trouble is that they all seem to be about different sUbjects! This book takes another approach. It brings together all the methods for assessing risk into a common framework, thus demonstrating how the various methods relate to one another. This produces four important benefits: • First, it provides a comprehensive reference for risk assessment. This one source offers readers concise explanations of the many methods currently available for describing and quantifying diverse types of risks. • Second, it consistently evaluates and compares available risk assessment methods and identifies their specific strengths and limitations. Understand ing the limitations of risk assessment methods is important. The field is still in its infancy, and the problems with available methods are disappoint ingly numerous. At the same time, risk assessment is being used.
Category: Technology & Engineering

Environmental Mycology In Public Health

Author : Carla Viegas
ISBN : 9780124115354
Genre : Science
File Size : 21.74 MB
Format : PDF
Download : 953
Read : 809

Environmental Mycology in Public Health: Fungi and Mycotoxins Risk Assessment and Management provides the most updated information on fungi, an essential element in the survival of our global ecology that can also pose a significant threat to the health of occupants when they are present in buildings. As the exposure to fungi in homes is a significant risk factor for a number of respiratory symptoms, including allergies and hypersensitivity pneumonitis, this book presents information on fungi and their disease agents, important aspects of exposure assessment, and their impacts on health. This book answers the hard questions, including, "How does one detect and measure the presence of indoor fungi?" and "What is an acceptable level of indoor fungi?" It then examines how we relate this information to human health problems. Provides unique new insights on fungi and their metabolites detection in the environmental and occupational settings Presents new information that is enriched by significant cases studies Multi-contributed work, edited by a proficient team in medical and environmental mycology with different individual expertise Guides the readers in the implementation of preventive and protective measures regarding exposure to fungi
Category: Science

Public Health Risk Assessment For Human Exposure To Chemicals

Author : K. Asante-Duah
ISBN : 1402009216
Genre : Medical
File Size : 22.95 MB
Format : PDF, ePub, Docs
Download : 521
Read : 821

Risks to humans as a consequence of chemical exposures are a complex issue with worldwide implications, especially in our modern societies. The effective management of human exposure to a variety of chemicals present in various sectors of society has indeed become a very important public health policy issue - and risk assessment promises a systematic way for developing appropriate strategies to aid public health risk management decisions. Risk assessment generally serves as a tool that can be used to organize, structure, and compile scientific information in order to help identify existing hazardous situations or problems, anticipate potential problems, establish priorities, and provide a basis for regulatory controls and/or corrective actions. In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health. This book provides a concise, yet comprehensive overview of the many facets/aspects relating to human health risk assessments in relation to chemical exposure problems. It presents some very important tools and methodologies that can be used to address chemical exposure and public health risk management problems in a consistent, efficient, and cost?effective way. Overall the book represents a collection and synthesis of the principal elements of the risk assessment process that pertain to human exposures to chemicals in the human living and work environments. It offers an understanding of the scientific basis of risk assessment and its applications to public health policy decisions. Audience: The subject matter of this book should be of interest to many a professional encountering risk assessment in relation to environmental contamination and public health risk management programs – especially public and occupational health practitioners; environmental consultants; environmental attorneys; public policy analysts; and various health, environmental, and consumer advocacy interest groups. The book is also expected to serve as a useful educational and training resource for both students and professionals in the health-related and environmental fields – who have to deal with human exposures to chemicals, public health risk assessment issues, and/or environmental health management problems.
Category: Medical

Risk Assessment And Decision Analysis With Bayesian Networks Second Edition

Author : Norman Fenton
ISBN : 9781351978965
Genre : Mathematics
File Size : 23.87 MB
Format : PDF, Docs
Download : 193
Read : 504

Since the first edition of this book published, Bayesian networks have become even more important for applications in a vast array of fields. This second edition includes new material on influence diagrams, learning from data, value of information, cybersecurity, debunking bad statistics, and much more. Focusing on practical real-world problem-solving and model building, as opposed to algorithms and theory, it explains how to incorporate knowledge with data to develop and use (Bayesian) causal models of risk that provide more powerful insights and better decision making than is possible from purely data-driven solutions. Features Provides all tools necessary to build and run realistic Bayesian network models Supplies extensive example models based on real risk assessment problems in a wide range of application domains provided; for example, finance, safety, systems reliability, law, forensics, cybersecurity and more Introduces all necessary mathematics, probability, and statistics as needed Establishes the basics of probability, risk, and building and using Bayesian network models, before going into the detailed applications A dedicated website contains exercises and worked solutions for all chapters along with numerous other resources. The AgenaRisk software contains a model library with executable versions of all of the models in the book. Lecture slides are freely available to accredited academic teachers adopting the book on their course.
Category: Mathematics

Numerical Methods And Applications

Author : Ivan Dimov
ISBN : 9783642184659
Genre : Computers
File Size : 63.4 MB
Format : PDF, ePub
Download : 802
Read : 1081

This book constitutes the thoroughly refereed post-conference proceedings of the 7th International Conference on Numerical Methods and Applications, NMA 2010, held in Borovets, Bulgaria, in August 2010. The 60 revised full papers presented together with 3 invited papers were carefully reviewed and selected from numerous submissions for inclusion in this book. The papers are organized in topical sections on Monte Carlo and quasi-Monte Carlo methods, environmental modeling, grid computing and applications, metaheuristics for optimization problems, and modeling and simulation of electrochemical processes.
Category: Computers