PRINCIPLES OF TISSUE ENGINEERING

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Principles Of Tissue Engineering

Author : Robert Lanza
ISBN : 0080548849
Genre : Science
File Size : 23.67 MB
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First published in 1997, Principles of Tissue Engineering is the widely recognized definitive resource in the field. The third edition provides a much needed update of the rapid progress that has been achieved in the field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike. New to this edition: *Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves *Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems
Category: Science

Principles Of Tissue Engineering

Author : Robert Lanza
ISBN : 9780080539676
Genre : Science
File Size : 74.68 MB
Format : PDF
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The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features * Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves * Essential to anyone working in the field * Educates and directs both the novice and advanced researcher * Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves * Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell * Considered the definitive reference in the field * List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others
Category: Science

Tissue Engineering

Author : W. Mark Saltzman
ISBN : 0198032404
Genre : Medical
File Size : 21.55 MB
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Tissue or organ transplantation are among the few options available for patients with excessive skin loss, heart or liver failure, and many common ailments, and the demand for replacement tissue greatly exceeds the supply, even before one considers the serious constraints of immunological tissue type matching to avoid immune rejection. Tissue engineering promises to help sidestep constraints on availability and overcome the scientific challenges, with huge medical benefits. This book lays out the principles of tissue engineering. It will be a useful reference work for those associated with this field and as a textbook for specialized courses in the subject. It is a companion volume to Saltzman's OUP book on drug delivery.
Category: Medical

Tissue Engineering

Author : John P. Fisher
ISBN : 9781439874035
Genre : Medical
File Size : 45.91 MB
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Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the field into a broad context, Tissue Engineering: Principles and Practices explores current thoughts on the development of engineered tissues. With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nanobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. A comprehensive overview of major research topics in tissue engineering, the book: Examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue-engineered devices Focuses upon those strategies typically incorporated into tissue-engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques Presents synthetic tissues and organs that are currently under development for regenerative medicine applications The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry. Furthermore, this book includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue-engineered devices. The book provides a useful reference for courses devoted to tissue engineering fundamentals and those laboratories developing tissue-engineered devices for regenerative medicine therapy.
Category: Medical

Bioreactors For Tissue Engineering

Author : Julian Chaudhuri
ISBN : 9781402037412
Genre : Medical
File Size : 75.50 MB
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For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for several tissue types (bone, cartilage, vascular), addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. This unique volume is dedicated to the fundamentals and application of bioreactor technology to tissue engineering products. Not only will it appeal to graduate students and experienced researchers in tissue engineering and regenerative medicine, but also to tissue engineers and culture technologists, academic and industrial chemical engineers, biochemical engineers and cell biologists who wish to understand the criteria used to design and develop novel systems for tissue growth in vitro.
Category: Medical

Methods Of Tissue Engineering

Author : Anthony Atala
ISBN : 9780124366367
Genre : Medical
File Size : 50.37 MB
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This book will be a resource for the experienced tissue engineer, a starting point for the student, and a guidebook for the next generation of tissue engineers. Contained in one volume is a comprehensive reference that combines the tools, experimental protocols, detailed descriptions, and "know-how" for the successful engineering of tissues and organs. The practical information contained in the numerous protocols covers every area of tissue engineering and will prove essential to scientists working in this field. Contributions by leaders in the latest areas of research will also be of interest to biotechnological and pharmaceutical researchers. Key Features * Provides comprehensive protocols covering every area of tissue engineering, including polymer synthesis, cell culture, encapsulation, bioreactors, therapeutics, and the creation of tissues and organs; * Includes contributions by leaders in the latest areas of research, such as stem cells and fetal tissue engineering
Category: Medical

Scaffolding In Tissue Engineering

Author : Peter X. Ma
ISBN : 9781420027563
Genre : Medical
File Size : 83.35 MB
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The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering. Scaffolding in Tissue Engineering reviews the general principles of tissue engineering and concentrates on the principles, methods, and applications for a broad range of tissue engineering scaffolds. The first section presents an in-depth exploration of traditional and novel materials, including alginates, polysaccharides, and fibrillar fibrin gels. The following section covers fabrication technologies, discussing three-dimensional scaffold design, laboratory-scale manufacture of a cell carrier, phase separation, self-assembly, gas foaming, solid freeform fabrication, injectable systems, and immunoisolation techniques. Subsequent chapters examine structural and functional scaffold modification, composite scaffolds, bioactive hydrogels, gene delivery, growth factors, and degradation of biodegradable polymers. The final section explores various tissue engineering applications, comprising chapters on blood cell substitutes, and tissue engineering of nerves, the tendons, ligaments, cornea, cartilage and myocardium, meniscal tissue. While providing a comprehensive summary of current knowledge and technologies, Scaffolding in Tissue Engineering gives readers insight into new trends and directions for scaffold development and for an ever-expanding range of tissue engineering applications.
Category: Medical

Principles Of Regenerative Medicine

Author : Anthony Atala
ISBN : 0080555950
Genre : Science
File Size : 78.61 MB
Format : PDF
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Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. * Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology * The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine * New discoveries from leading researchers on restoration of diseased tissues and organs
Category: Science

Tissue Engineering

Author : Bernhard Palsson
ISBN : 0849318122
Genre : Medical
File Size : 29.65 MB
Format : PDF, Kindle
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A volume in the new Principles and Applications in Engineering series, Tissue Engineering provides an overview of the major physiologic systems of current interest to biomedical engineers: cardiovascular, endocrine, nervous, visual, auditory, gastrointestinal, and respiratory. It contains useful definitions, tables of basic physiologic data, and an introduction to the literature. Then, the book reviews the status of tissue engineering of specific organs, including bone marrow, skeletal muscle, and cartilage. Readers will acquire a good understanding of the engineering and cell biological fundamentals of tissue engineering and will develop ideas for further development of this emerging and important field.
Category: Medical