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Molecular Virology Of Human Pathogenic Viruses

Author : Wang-Shick Ryu
ISBN : 9780128009994
Genre : Science
File Size : 69.18 MB
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Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author’s more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. Presents viruses within their family structure Contains recommended journal articles with perspectives to put primary literature in context Includes integrated recommended reading references within each chapter Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor’s manual, study guide, and test bank
Category: Science

Fundamentals Of Molecular Virology 2nd Edition

Author : Nicholas H. Acheson
ISBN : 9781118213827
Genre : Science
File Size : 65.31 MB
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Designed for students learning about viruses for the first time at the undergraduate or graduate level, Fundamentals of Molecular Virology is presented in a style which relates to today's students and professors. This book is also a valuable, up-to-date source of information for graduate students, postdoctoral fellows and research scientists working with viruses. Chapters contributed by prominent virologists were edited to conform to a clear and accessible style. The text provides a thorough presentation of basic and contemporary concepts in virology for a student's first exposure to the field.
Category: Science

Principles Of Molecular Virology

Author : Alan J. Cann
ISBN : 9780128019559
Genre : Science
File Size : 49.96 MB
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Principles of Molecular Virology, Sixth Edition, provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. This fully updated edition explores and explains the fundamental aspects of virology, including the structure of virus particles and genome, replication, gene expression, infection, pathogenesis and subviral agents. In addition, this update reflects advances made in the field, including HIV pathogenesis, cryoelectron microscopy, bioinformatics, and RNA interference. Provides a conceptual approach to the principles of molecular virology, with important examples of new advances in virology Includes online resources for students and instructors New concepts in this edition include coverage of newly discovered and emergent viruses such as MERS and Ebola Presents new and updated information on bioinformatics and metagenomics Contains updated learning outcomes and further reading for each chapter
Category: Science


Author : Sandra Knowles Weller
ISBN : 9781904455769
Genre : Science
File Size : 62.4 MB
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Alphaherpesviruses are a fascinating group of DNA viruses that include important human pathogens, such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV) - the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive study distills the most important research in this area, providing a timely overview of the field. Topics include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection, and oncolytic vectors for cancer therapy. In addition, there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity, and vaccine development. This is essential reading for everyone working with alphaherpesviruses and will be of interest to all virologists working on latent infections.
Category: Science

Human Virology

Author : Leslie Collier
ISBN : 9780198714682
Genre :
File Size : 89.70 MB
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Viruses are some of the simplest infectious agents on the planet, yet can cause severe and even life-threatening diseases in all forms of life - including humans. Despite relying on host cells in order to replicate, viruses can be capable of extremely rapid reproduction and very effective transmission from one person to another. Because of this, they have historically represented a significant proportion of the disease burden affectinghumans.Human Virology provides a vivid introduction to this fascinating field, by incorporating both the molecular and clinical aspects of the subject. Throughout the text, case studies bring the subject tolife by providing a unique perspective from real practicing doctors. In addition new 'hot topic' boxes have been incorporated into this edition, featuring current important areas of research. Little prior knowledge is assumed, making Human Virology the perfect text for those students new to the subject.


Author : Qinghua Wang
ISBN : 9781904455578
Genre : Medical
File Size : 50.25 MB
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In this timely book, internationally renowned scientists critically review the current research and the most important discoveries in this highly topical field.
Category: Medical

Structure Function Relationships Of Human Pathogenic Viruses

Author : Andreas Holzenburg
ISBN : 9780306476501
Genre : Medical
File Size : 69.10 MB
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Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis. Furthermore Structure-Function Relationships of Human Pathogenic Viruses illustrates in a single volume the fundamental processes involved in viral life cycles using up-to-date information from research laboratories around the world. Knowledge of these processes is crucial to develop rationales for the design of future drugs. The timeliness of the data and the comprehensive yet concise approach this book takes in order to present the world of viral pathogens should make it a frontrunner in higher education and R&D.
Category: Medical

Molecular Virology And Control Of Flaviviruses

Author : Pei-Yong Shi
ISBN : 9781904455929
Genre : Medical
File Size : 74.28 MB
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Flaviviruses are a diverse group of small RNA enveloped viruses, many of which are important human and animal pathogens. The best known include dengue virus, yellow fever virus, Japanese encephalitis virus, and West Nile virus. These viruses are endemic in many tropical and sub-tropical regions of the world. Dengue virus alone infects over 100 million people annually. In recent years, research on flaviviruses has progressed at a remarkable rate, leading to significant advances in our understanding of virus biology. This should ultimately lead to the development of better vaccine and antiviral strategies. This up-to-date and cutting-edge anthology contains contributions from the leading experts in the flavivirus field. Chapters are balanced by contributions from established investigators who have dedicated their careers to flavivirus research with those from newcomers who have recently made significant contributions to the flavivirus field. The book is divided into two sections: Molecular Virology and Virus Prevention. The first section on Molecular Virology covers: virion structure * virus replication * the NS1 glycoprotein * the NS3 protein * the NS5 protein * innate immunity and flavivirus infection * host responses to flavivirus infection * flavivirus fitness and transmission. The Virus Prevention section includes: vaccines * antibody therapy * small molecule antiviral development * flavivirus diagnostics * vector-virus interactions * vector control. The book represents an important update of flavivirus research and will serve as a reference to flavivirus researchers at the graduate level and beyond. It is a recommended text for all virology libraries.
Category: Medical


Author : Benhur Lee
ISBN : 9783642298196
Genre : Medical
File Size : 27.93 MB
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Henipaviruses form a new genus of emerging paramyxoviruses that are the deadliest human pathogens within the Paramyxoviridae family. This volume deals with the many facets of henipavirus biology, and covers our current understanding regarding the ecology, molecular virology, and pathogenesis of henipavirus infections. It is an international effort written by a multidisciplinary panel of experts at the front lines of research into this lethal emerging group of paramyxoviruses. The first section introduces the epidemiology and ecology of Nipah and Hendra viruses in their respective endemic areas, including a first-hand account of the discovery of Nipah virus during its initial outbreak in Malaysia; the next section documents the molecular virology of henipaviruses, and the substantial advances made towards understanding the unique features of henipavirus entry and tropism; and this is followed by accounts of the clinical and pathologic features of henipavirus infections in their human and naturally infected animal hosts. The next sections on pathogenesis provide a comprehensive reference on how henipaviruses counteract the innate immune system, and the relevant pathogenic features in animal challenge models developed to test potential therapeutic strategies. The final sections describe our current and future capabilities for diagnosis and control, including an account of potentially effective immunization strategies that are currently being tested. This book will not only serve as a useful reference for the henipavirus field; it will be useful to basic and animal virologists, ecologists, epidemiologists, physicians, and others interested in emerging infectious viral diseases, as it showcases the multidisciplinary efforts required to understand the genesis, spread and hopefully, control, of a group of lethal emerging zoonotic pathogens.
Category: Medical

Animal Viruses

Author : Thomas C. Mettenleiter
ISBN : 9781904455226
Genre : Science
File Size : 37.3 MB
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The study of animal viruses contributes to the general understanding of the molecular basis of viral infection. The emergence of the SARS (Severe Acute Respiratory Syndrome) virus in the human population, coming from an animal source, highlights the importance of animals in harboring infectious agents. In addition, it has been recognized recently that influenza viruses, which persist in their natural avian host, can directly infect humans. In this book, an international panel of leading virologists provide a state-of-the-art overview of the field, comprehensively detailing the current understanding of viruses, their replication, evolution, and interaction with the host. The authors emphasize strategic and methodological aspects of current research, and provide key related references. Topics include foot-and-mouth disease virus, Pestivirus, Arteriviridae, Coronaviruses (including SARS), Herpesviridae, Paramyxoviridae, influenza viruses, Reoviridae, porcine circoviruses, Asfarviridae and much more.
Category: Science