MOLECULAR VIROLOGY OF HUMAN PATHOGENIC VIRUSES

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Molecular Virology Of Human Pathogenic Viruses

Author : Wang-Shick Ryu
ISBN : 9780128009994
Genre : Science
File Size : 25.14 MB
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Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author’s more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. Presents viruses within their family structure Contains recommended journal articles with perspectives to put primary literature in context Includes integrated recommended reading references within each chapter Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor’s manual, study guide, and test bank
Category: Science

Principles Of Molecular Virology

Author : Alan Cann
ISBN : 9780123849397
Genre : Science
File Size : 87.45 MB
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The fifth edition of the highly successful Principles of Molecular Virology takes on a molecular approach to the explanation of virology, presenting basic in a clear, concise and student-friendly manner. This fully updated undergraduate text explores and explains the fundamental aspects of virology, including structure of virus particles and genome, replication, gene expression, infection, pathogenesis and subviral agents. A website with self-assessment questions and other resources aids in student understanding. Completely rewritten and updated Clear and easy to understand Examples covering important ideas in virology All new illustrations Accompanying website with interactive resources and teaching material for instructors
Category: Science

Fundamentals Of Molecular Virology

Author : Nicholas H. Acheson
ISBN : 0471351512
Genre : Science
File Size : 81.29 MB
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Designed for students learning about viruses for the first time(t the undergraduate or graduate level), Fundamentals of Molecular Virology is presented in a style which relates to today's students and professors. The text approaches learning about virology by presenting a set of chapters each of which covers a specific virus family, using one or two well-studied viruses as examples. Each chapter is designed to tell a story about the virus under discussion, and to portray the "personality" of that virus. The text incorporates lessons from classic and contemporary concepts providing a well-rounded presentation on the subject of virology. FEATURES OF FUNDAMENTALS OF MOLECULAR VIROLOGY * Unique, Applied Chapter Stories. Each chapter presents a unique example or case to help introduce the students to the different viruses that will be studied or examined in that chapter. * Evolutionary Boxes. Feature exciting and current developments in molecular virology. These are integrated throughout the entire book and can be found in every chapter. These help students understand the importance of currency and application of virology. * Comprehensive, Illustrative Art Program. The text contains a number of two-color figures which focus on the individual steps in virus replication and helps draw student's attention to important concepts and details. * Coverage of Human Pathogens. Includes chapters that cover important human pathogens such as smallpox virus, measles virus, poliovirus, herpes viruses, human immunodeficiency virus, hepatitis B virus, Ebola virus, SARS corona virus, West Nile virus, and others. What instructors are saying about Fundamentals of Molecular Virology "I like the structured treatment that is presented in Acheson. Overall, it is one of the best written and clearly organized texts on the subject I have seen." - Jeannine Williams, College of Marin "I found the text very readable and believe it will appeal to a wide audience of students...I believe this text will have broad appeal in a field where few texts exist." - Michael Roner, The University of Texas at Arlington "The main strength of the book is the great molecular detail the author achieves, but still at a level that an undergraduate student should be able to master. I like the blend of molecular with medical; this has been lacking in most virology books that I have considered using." - Darlene Walro, Walsh University
Category: Science

Alphaherpesviruses

Author : Sandra Knowles Weller
ISBN : 9781904455769
Genre : Science
File Size : 58.56 MB
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Alphaherpesviruses are a fascinating group of DNA viruses that include important human pathogens, such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV) - the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive study distills the most important research in this area, providing a timely overview of the field. Topics include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection, and oncolytic vectors for cancer therapy. In addition, there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity, and vaccine development. This is essential reading for everyone working with alphaherpesviruses and will be of interest to all virologists working on latent infections.
Category: Science

Henipavirus

Author : Benhur Lee
ISBN : 9783642298196
Genre : Medical
File Size : 32.27 MB
Format : PDF
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Henipaviruses form a new genus of emerging paramyxoviruses that are the deadliest human pathogens within the Paramyxoviridae family. This volume deals with the many facets of henipavirus biology, and covers our current understanding regarding the ecology, molecular virology, and pathogenesis of henipavirus infections. It is an international effort written by a multidisciplinary panel of experts at the front lines of research into this lethal emerging group of paramyxoviruses. The first section introduces the epidemiology and ecology of Nipah and Hendra viruses in their respective endemic areas, including a first-hand account of the discovery of Nipah virus during its initial outbreak in Malaysia; the next section documents the molecular virology of henipaviruses, and the substantial advances made towards understanding the unique features of henipavirus entry and tropism; and this is followed by accounts of the clinical and pathologic features of henipavirus infections in their human and naturally infected animal hosts. The next sections on pathogenesis provide a comprehensive reference on how henipaviruses counteract the innate immune system, and the relevant pathogenic features in animal challenge models developed to test potential therapeutic strategies. The final sections describe our current and future capabilities for diagnosis and control, including an account of potentially effective immunization strategies that are currently being tested. This book will not only serve as a useful reference for the henipavirus field; it will be useful to basic and animal virologists, ecologists, epidemiologists, physicians, and others interested in emerging infectious viral diseases, as it showcases the multidisciplinary efforts required to understand the genesis, spread and hopefully, control, of a group of lethal emerging zoonotic pathogens.
Category: Medical

Influenza

Author : Qinghua Wang
ISBN : 9781904455578
Genre : Medical
File Size : 51.41 MB
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In this timely book, internationally renowned scientists critically review the current research and the most important discoveries in this highly topical field.
Category: Medical

Molecular Virology And Control Of Flaviviruses

Author : Pei-Yong Shi
ISBN : 9781904455929
Genre : Medical
File Size : 47.94 MB
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Flaviviruses are a diverse group of small RNA enveloped viruses, many of which are important human and animal pathogens. The best known include dengue virus, yellow fever virus, Japanese encephalitis virus, and West Nile virus. These viruses are endemic in many tropical and sub-tropical regions of the world. Dengue virus alone infects over 100 million people annually. In recent years, research on flaviviruses has progressed at a remarkable rate, leading to significant advances in our understanding of virus biology. This should ultimately lead to the development of better vaccine and antiviral strategies. This up-to-date and cutting-edge anthology contains contributions from the leading experts in the flavivirus field. Chapters are balanced by contributions from established investigators who have dedicated their careers to flavivirus research with those from newcomers who have recently made significant contributions to the flavivirus field. The book is divided into two sections: Molecular Virology and Virus Prevention. The first section on Molecular Virology covers: virion structure * virus replication * the NS1 glycoprotein * the NS3 protein * the NS5 protein * innate immunity and flavivirus infection * host responses to flavivirus infection * flavivirus fitness and transmission. The Virus Prevention section includes: vaccines * antibody therapy * small molecule antiviral development * flavivirus diagnostics * vector-virus interactions * vector control. The book represents an important update of flavivirus research and will serve as a reference to flavivirus researchers at the graduate level and beyond. It is a recommended text for all virology libraries.
Category: Medical

Essential Human Virology

Author : Jennifer Louten
ISBN : 9780128011713
Genre : Science
File Size : 69.3 MB
Format : PDF
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Essential Human Virology is written for the undergraduate level with case studies integrated into each chapter. The structure and classification of viruses will be covered, as well as virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters will focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses, and emerging and dangerous viruses. Additionally, how viruses cause disease, or pathogenesis, will be highlighted during the discussion of each virus family, and a chapter on the immune response to viruses will be included. Further, research laboratory assays and viral diagnosis assays will be discussed, as will vaccines, anti-viral drugs, gene therapy, and the beneficial uses of viruses. By focusing on general virology principles, current and future technologies, familiar human viruses, and the effects of these viruses on humans, this textbook will provide a solid foundation in virology while keeping the interest of undergraduate students. Focuses on the human diseases and cellular pathology that viruses cause Highlights current and cutting-edge technology and associated issues Presents real case studies and current news highlights in each chapter Features dynamic illustrations, chapter assessment questions, key terms, and summary of concepts, as well as an instructor website with lecture slides, test bank, and recommended activities
Category: Science

Human Virology

Author : Leslie Collier
ISBN : 9780198714682
Genre :
File Size : 49.93 MB
Format : PDF
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Viruses are some of the simplest infectious agents on the planet, yet can cause severe and even life-threatening diseases in all forms of life - including humans. Despite relying on host cells in order to replicate, viruses can be capable of extremely rapid reproduction and very effective transmission from one person to another. Because of this, they have historically represented a significant proportion of the disease burden affectinghumans.Human Virology provides a vivid introduction to this fascinating field, by incorporating both the molecular and clinical aspects of the subject. Throughout the text, case studies bring the subject tolife by providing a unique perspective from real practicing doctors. In addition new 'hot topic' boxes have been incorporated into this edition, featuring current important areas of research. Little prior knowledge is assumed, making Human Virology the perfect text for those students new to the subject.
Category:

Viruses

Author : Paula Tennant
ISBN : 9780128111949
Genre : Science
File Size : 36.72 MB
Format : PDF
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Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived ‘interactomics’ as defined by the molecules and the processes by which virus gene products interact with themselves and their host’s cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses Provides key insights into recent technological advances, including high-throughput sequencing Presents viruses not only as formidable foes, but also as entities that can be beneficial to their hosts and humankind that are helping to shape the tree of life Features exposition on the diversity and versatility of viruses, how they cause disease, and an exploration of virus-host interactions
Category: Science