MODELLING METABOLISM WITH MATHEMATICA

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Modelling Metabolism With Mathematica

Author : Peter Mulquiney
ISBN : 9780203503935
Genre : Science
File Size : 48.1 MB
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With the advent of sophisticated general programming environments like Mathematica, the task of developing new models of metabolism and visualizing their responses has become accessible to students of biochemistry and the life sciences in general. Modelling Metabolism with Mathematica presents the approaches, methods, tools, and algorithms for modelling the chemical-dynamics of metabolic pathways. The authors explain the concepts underpinning the deterministic theory of chemical and enzyme kinetics, present a graded series of computer models of metabolic pathways leading up to that of the human erythrocyte, and document a consistent set of rate equations and associated kinetic parameters. The experimental and theoretical study of metabolism in mammalian cells has a long and fruitful history, but our understanding of cellular metabolism at the molecular level is far from complete. This book enables its readers to formulate their own models of time-dependent metabolic systems and aids them in the quest for the many fundamental and clinically relevant discoveries that remain to be made.
Category: Science

Bioengineering And Molecular Biology Of Plant Pathways

Author :
ISBN : 0080556965
Genre : Science
File Size : 28.57 MB
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The increased knowledge about the structure of genomes in a number of species, about the complexity of transcriptomes, and the rapid growth in knowledge about mutant phenotypes have set off the large scale use of transgenes to answer basic biological questions, and to generate new crops and novel products. Bioengineering and Molecular Biology of Plant Pathways includes twelve chapters, which to variable degrees describe the use of transgenic plants to explore possibilities and approaches for the modification of plant metabolism, adaptation or development. The interests of the authors range from tool development, to basic biochemical know-how about the engineering of enzymes, to exploring avenues for the modification of complex multigenic pathways, and include several examples for the engineering of specific pathways in different organs and developmental stages. Prologue by Paul K. Stumpf and Eric E. Conn Incorporates new concepts and insights in plant biochemistry and biology Provides a conceptual framework regarding the challenges faced in engineering pathways Discusses potential in engineering of metabolic end-products that are of vast economical importance, including genetic engineering of cellulose, seed storage proteins, and edible and industrial oils
Category: Science

Nostradamus 2013 Prediction Modeling And Analysis Of Complex Systems

Author : Ivan Zelinka
ISBN : 9783319005423
Genre : Computers
File Size : 24.47 MB
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Prediction of behavior of the dynamical systems, analysis and modeling of its structure is vitally important problem in engineering, economy and science today. Examples of such systems can be seen in the world around us and of course in almost every scientific discipline including such “exotic” domains like the earth’s atmosphere, turbulent fluids, economies (exchange rate and stock markets), population growth, physics (control of plasma), information flow in social networks and its dynamics, chemistry and complex networks. To understand such dynamics and to use it in research or industrial applications, it is important to create its models. For this purpose there is rich spectra of methods, from classical like ARMA models or Box Jenkins method to such modern ones like evolutionary computation, neural networks, fuzzy logic, fractal geometry, deterministic chaos and more. This proceeding book is a collection of the accepted papers to conference Nostradamus that has been held in Ostrava, Czech Republic. Proceeding also comprises of outstanding keynote speeches by distinguished guest speakers: Guanrong Chen (Hong Kong), Miguel A. F. Sanjuan (Spain), Gennady Leonov and Nikolay Kuznetsov (Russia), Petr Škoda (Czech Republic). The main aim of the conference is to create periodical possibility for students, academics and researchers to exchange their ideas and novel methods. This conference will establish forum for presentation and discussion of recent trends in the area of applications of various predictive methods for researchers, students and academics.
Category: Computers

Enzyme Kinetics

Author : Robert A. Alberty
ISBN : 1118002156
Genre : Science
File Size : 67.80 MB
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Rapid-Equilibrium Enzyme Kinetics helps readers emphasize the estimation of kinetic parameters with the minimum number of velocity measurements, thereby reducing the amount of laboratory work necessary, and allowing more time for the consideration of complicated mechanisms. The book systematically progresses through six levels of understanding the enzyme-catalyzed reaction, and includes a CD-ROM so that the reader may use the programs in the book to input their own experimental data.
Category: Science

Enzyme Kinetics Catalysis And Control

Author : Daniel L. Purich
ISBN : 9780123809254
Genre : Science
File Size : 28.66 MB
Format : PDF
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Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. Historical analysis of kinetic principles including advanced enzyme science Provides both theoretical and practical measurements tools Coverage of single molecular kinetics Examination of force generation mechanisms Discussion of organic and inorganic enzyme reactions
Category: Science

Who S Who In Australia

Author : Suzannah Pearce
ISBN : 1740951301
Genre : Australia
File Size : 52.82 MB
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Category: Australia

Systems Biology

Author : Olaf Wolkenhauer
ISBN : UOM:39015080770004
Genre : Medical
File Size : 21.38 MB
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Contains topics including modelling the dynamics of signalling pathways, modelling metabolic networks using power-laws and S-systems, modelling reaction kinetics in cells, the regulatory design of cellular processes, metabolomics and fluxomics, modelling cellular signalling systems, and systems analysis of MAPK signal transduction.
Category: Medical