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Advanced Genetic Analysis

Author : R. Scott Hawley
ISBN : 9781444313086
Genre : Science
File Size : 55.33 MB
Format : PDF, ePub, Mobi
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Advanced Genetic Analysis brings a state-of-the-art, exciting new approach to genetic analysis. Focusing on the underlying principles of modern genetic analysis, this book provides the 'how' and 'why' of the essential analytical tools needed. The author's vibrant, accessible style provides an easy guide to difficult genetic concepts, from mutation and gene function to gene mapping and chromosome segregation. Throughout, a balanced range of model organisms and timely examples are used to illustrate the theoretical basics. Basic principles - Focuses students attention on the 'how' and 'why' of the essential analytical tools. Vibrant, accessible style provides an easy guide through difficult genetic concepts and techniques. Text boxes highlight key questions and timely examples. Boxes of key information in each chapter, chapter summaries and extensive references - prompt the student to synthesise and reinforce the chapter material. Special reference section addressing a range of model organisms to help provide a particularly relevant context for students' research interests.
Category: Science

Introduction To Genetic Analysis

Author : Anthony J.F. Griffiths
ISBN : 0716768879
Genre : Science
File Size : 40.39 MB
Format : PDF, Mobi
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Provides an introduction to genetic analysis. This book covers contemporary genetics, and helps students understand the essentials of genetics, featuring various experiments, teaching them how to analyze data, and how to draw their own conclusions
Category: Science

Genetic Analysis

Author : Philip Meneely
ISBN : 9780199651818
Genre : Medical
File Size : 85.7 MB
Format : PDF, ePub, Docs
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How do we know what role a particular gene has? How do some genes control the expression of others? How do genes interact to form gene networks? With its unique integration of genetics and molecular biology, Genetic Analysis probes fascinating questions such as these, detailing how our understanding of key genetic phenomena can be used to understand biological systems. Opening with a brief overview of key genetic principles, model organisms, and epigenetics, the book goes on to explorethe use of gene mutations and the analysis of gene expression and activity. A discussion of the genetic structure of natural populations follows, before the interaction of genes during suppression and epistasis, how we study gene networks, and personalized genomics are considered. Drawing on the latest experimental tools, including microarrays, RNAi screens, and bioinformatics approaches, Genetic Analysis provides a state-of-the-art review of the field, but in a truly student-friendly manner. It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research, without losing clarity of explanation and insight. We are in an age where, despite knowing so much about biological systems, we are just beginning to realise how much more there is still to understand. Genetic Analysis is the ideal guide to how we can use the awesome power of molecular genetics to further our understanding. Online Resource Centre: The Online Resource Centre to accompany Genetic Analysis features the following resources for teachers and students: For students: * Topical updates - key updates on topics or tools presented in the book, to keep you up-to-date with the latest developments in the field. * Additional case studies and text boxes to complement and add to those found in the book. * Practice problems, to test the reader's knowledge of the concepts presented, and help to master them. For registered adopters ofthe book: * Figures from the book in electronic format, ready to download. * Journal clubs - suggested papers and discussion questions linked to topics covered in the book.
Category: Medical

Genetic Analysis

Author : John R. S. Fincham
ISBN : 9781444313826
Genre : Science
File Size : 58.94 MB
Format : PDF
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Authored by a very eminent geneticist, this text gives students a thorough appreciation of the development and potential of analytical genetic techniques. Beginning with a consideration of both the classical Mendelian and the molecular biological aspects of genetic analysis, the book goes on to discuss progress in three key areas of genetics. Firstly the elucidation of the detailed structure and overall organization of the genome, secondly the way that genetic differences at the molecular level account for heritable variation in populations, and finally an explanation of how the genes control the metabolism and development of the whole organism. Professor Fincham takes as his theme the links between classical and molecular genetics, and throughout the book shows how the combination of these two approaches can be a powerful tool for the advancement of genetic research. A clear and simple text from one of the world's leading geneticists Abundant and innovative illustrations Links classical Mendelian genetics with the new molecular genetic techniques
Category: Science

Modern Genetic Analysis

Author : Anthony J.F. Griffiths
ISBN : 0716743825
Genre : Science
File Size : 67.99 MB
Format : PDF
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Part 1: Fundamentals of gene structure, function, and transmission; Genetics and the organism; The structure of genes and genomes; Gene function; The transmission of DNA at cell division; The inheritance of single-gene differences; Genetic recombination in eukaryotes; Recombination in bacteria and their viruses. Part 2: Methods of genetic manipulation; Recombinant DNA and genetic engineering; Genomics; Gene mutation: origins and repair processes; Chromosome mutations; Mutation dissection. Part 3: Systems genetics: from gene to phenotype; Regulation of hene transciption; From gene to phenotype; Regulation of cell number: normal and cancer cells; The genetic basis of development. Part 4: Genetic analysis of populations; Population genetics; Quantitative genetics; Evolutionary genetics.
Category: Science

Mathematical And Statistical Methods For Genetic Analysis

Author : Kenneth Lange
ISBN : 9781475727395
Genre : Mathematics
File Size : 43.33 MB
Format : PDF, Kindle
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Geneticists now stand on the threshold of sequencing the genome in its entirety. The unprecedented insights into human disease and evolution offered by mapping and sequencing are transforming medicine and agriculture. This revolution depends vitally on the contributions made by applied mathematicians, statisticians, and computer scientists. Kenneth Lange has written a book to enable graduate students in the mathematical sciences to understand and model the epidemiological and experimental data encountered in genetics research. Mathematical, statistical, and computational principles relevant to this task are developed hand-in-hand with applications to gene mapping, risk prediction, and the testing of epidemiological hypotheses. The book covers many topics previously only accessible in journal articles, such as pedigree analysis algorithms, Markov chain, Monte Carlo methods, reconstruction of evolutionary trees, radiation hybrid mapping, and models of recombination. The whole is backed by numerous exercise sets.
Category: Mathematics

Primer Of Genetic Analysis

Author : James N. Thompson, Jr
ISBN : 1139465643
Genre : Science
File Size : 29.26 MB
Format : PDF, Kindle
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An invaluable student-tested study aid, this primer, first published in 2007, provides guided instruction for the analysis and interpretation of genetic principles and practice in problem solving. Each section is introduced with a summary of useful hints for problem solving and an overview of the topic with key terms. A series of problems, generally progressing from simple to more complex, then allows students to test their understanding of the material. Each question and answer is accompanied by detailed explanation. This third edition includes additional problems in basic areas that often challenge students, extended coverage in molecular biology and development, an expanded glossary of terms, and updated historical landmarks. Students at all levels, from beginning biologists and premedical students to graduates seeking a review of basic genetics, will find this book a valuable aid. It will complement the formal presentation in any genetics textbook or stand alone as a self-paced review manual.
Category: Science

Genetic Analysis

Author : Mark F. Sanders
ISBN : 0134605179
Genre : Genetics
File Size : 59.49 MB
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The molecular basis of heredity, variation, and evolution -- Transmission genetics -- Cell division and chromosome heredity -- Gene interaction -- Genetic linkage and mapping in eukaryotes -- Genetic analysis and mapping in bacteria and bacteriophages -- DNA structure and replication -- Molecular biology of transcription and RNA processing -- The molecular biology of translation -- Eukaryotic -chromosome abnormalities and molecular organization -- Gene mutation, DNA repair, and homologous recombination -- Regulation of gene expression in bacteria and bacteriophage -- Regulation of gene -expression in eukaryotes -- Analysis of gene function by forward genetics and reverse genetics -- Recombinant DNA technology and its applications -- Genomics : genetics from a whole-genome perspective -- Organellar inheritance and the evolution of organellar genomes -- Developmental genetics -- Genetic analysis of -quantitative traits -- Population genetics and evolution at the population, species, and molecular levels
Category: Genetics

Genetic Analysis

Author : Raphael Falk
ISBN : 9780521884181
Genre : Philosophy
File Size : 89.42 MB
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There is a paradox lying at the heart of the study of heredity. To understand the ways in which features are passed on down from one generation to the next, we have to dig deeper and deeper into the ultimate nature of things - from organisms, to genes, to molecules. And yet as we do this, increasingly we find we are out of focus with our subjects. What has any of this to do with the living, breathing organisms with which we started? Organisms are living. Molecules are not. How do we relate one to the other? In Genetic Analysis, one of the most important empirical scientists in the field in the twentieth century attempts, through a study of history and drawing on his own vast experience as a practitioner, to face this paradox head-on. His book offers a deep and innovative understanding of our ways of thinking about heredity.
Category: Philosophy

Introduction To Genetic Analysis Solutions Megamanual

Author : William Fixen
ISBN : 1429201770
Genre : Science
File Size : 52.67 MB
Format : PDF, ePub
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The solutions mega manual contains complete worked-out solutions to all the problems in the textbook. Used in conjunction with the main text, this manual is one of the best ways to develop a fuller appreciation of genetic principles.
Category: Science