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Ethnomedicine And Drug Discovery

Author : M.M. Iwu
ISBN : 0080531253
Genre : Medical
File Size : 73.76 MB
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The emergence of new infectious, chronic and drug resistant diseases have prompted scientists to look towards medicinal plants as agents for treatment and prevention. This book provides an interphase between ethnomedical and ethnobotanical approaches to new drug discovery and advances in biotechnology and molecular science that has made it increasingly feasible to transform traditional medicines into modern drugs. These novel approaches also raise new issues and the volume explores economic, ethical and policy considerations of drug development based on indigenous knowledge or traditional medicine. This work also features standardization and development of phytomedicines for major therapeutic indications, including emerging infectious diseases affecting developing and developed countries. The publication provides state-of-the-art information on the most innovative science, the research, the industry, the market, and the future of ethnomedicine and drug discovery.
Category: Medical

Lead Molecules From Natural Products

Author :
ISBN : 0080459331
Genre : Science
File Size : 42.51 MB
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Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.
Category: Science

Naturally Occurring Bioactive Compounds

Author :
ISBN : 0080464920
Genre : Science
File Size : 20.2 MB
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This timely book provides an overview of natural products/botanicals used for the management of insect-pest and diseases. It will help readers to update and widen their knowledge about natural products and their bio-activities against plant pathogens. The volume explores activity, chemistry, toxicity and geographic distribution of plants. Discussions concerning the methodology used for the detection of active principles, their mode of action and commercial prospects are of utmost importance and worthy of note. Focuses on recent achievements in natural bio-actives Global coverage of natural products / plants Targets the most important issues of natural botanicals/ biocides Includes innovative ideas with lucid explanations Contains specialized chapters, such as, natural control of multi-drug resistant organisms, anti-salmonella agents, natural house-dust-mite control agents, and naturally occurring anti-insect proteins, etc. Covers research on bioactives: From Lab to Field and Field to Market Includes eco-friendly and economically viable herbal technology
Category: Science

New Look To Phytomedicine

Author : Mohd Sajjad Ahmad Khan
ISBN : 9780128146200
Genre : Medical
File Size : 80.4 MB
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New Look to Phytomedicine: Advancements in Herbal Products as Novel Drug Leads is a compilation of in-depth information on the phytopharmaceuticals used in modern medicine for the cure and management of difficult-to-treat and challenging diseases. Readers will find cutting-edge knowledge on the use of plant products with scientific validation, along with updates on advanced herbal medicine in pharmacokinetics and drug delivery. This authoritative book is a comprehensive collection of research based, scientific validations of bioactivities of plant products, such as anti-infective, anti-diabetic, anti-cancer, immune-modulatory and metabolic disorders presented by experts from across the globe. Step-by-step information is presented on chemistry, bioactivity and the functional aspects of biologically active compounds. In addition, the pharmacognosy of plant products with mechanistic descriptions of their actions, including pathogenicity is updated with information on the use of nanotechnology and molecular tools in relation to herbal drug research. Compiles up-to-date information on the chemotherapeutics used in the treatment of infective and metabolic disorders Presents advancements in the discovery of new drugs from plants using molecular and nanotechnology tools Examines detailed information on the use of herbals agents in cancer, HIV and other ailments, including diabetes, malaria and neurological disorders
Category: Medical

Status And Potential Of Commercial Bioprospecting Activities In Latin America And The Caribbean

Author : Fernando Santibáñez Quezada
ISBN : 9211216486
Genre : Technology & Engineering
File Size : 46.19 MB
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The increasing availability of new scientific and technological tools have enabled new levels of precision and effectiveness in the identification, collection, processing and utilization of novel substances for applications in medical, agricultural or industrial applications. The present report provides an introductory overview of biodiversity prospecting in terms of the principles and practices which have defined it both historically and currently. Discussion is offered regarding the stakeholders and the issues involved in the formulation of national policy, particularly with regard to the implementation of provisions of the Convention on Biological Diversity. These include issues of access and benefit sharing, recognition of indigenous knowledge, prior informed consent, intellectual property protection and others.
Category: Technology & Engineering

Time And Complexity In Historical Ecology

Author : William L. Balée
ISBN : 9780231509619
Genre : Science
File Size : 22.93 MB
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This collection of studies by anthropologists, botanists, ecologists, and biologists is an important contribution to the emerging field of historical ecology. The book combines cutting-edge research with new perspectives to emphasize the close relationship between humans and their natural environment. Contributors examine how alterations in the natural world mirror human cultures, societies, and languages. Treating the landscape like a text, these researchers decipher patterns and meaning in the Ecuadorian Andes, Amazonia, the desert coast of Peru, and other regions in the neotropics. They show how local peoples have changed the landscape over time to fit their needs by managing and modifying species diversity, enhancing landscape heterogeneity, and controlling ecological disturbance. In turn, the environment itself becomes a form of architecture rich with historical and archaeological significance. Time and Complexity in Historical Ecology explores thousands of years of ecological history while also addressing important contemporary issues, such as biodiversity and genetic variation and change. Engagingly written and expertly researched, this book introduces and exemplifies a unique method for better understanding the link between humans and the biosphere.
Category: Science

Advances In Drug Discovery Techniques

Author : Alan L. Harvey
ISBN : 0471975095
Genre : Medical
File Size : 65.35 MB
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A guide to techniques for the discovery and evaluation of pharamcologically active compounds for therapeutic development, this book covers rational drug design, high-throughput screening, and genetic approaches to drug discovery. The authors focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. They examine typical screening studies and their link to robotics and informatics in detail and present an overview of current progress within anitsense therapeutics. The book explores the rapid changes in drug discovery resulting from developments in molecular biology, robotics, and informatics.
Category: Medical

Modern Phytomedicine

Author : Iqbal Ahmad
ISBN : 9783527609536
Genre : Medical
File Size : 81.44 MB
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This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.
Category: Medical


Author : National Society of Ethnopharmacology (India). National Conference
ISBN : 8170355648
Genre : Ethnopharmacology
File Size : 83.39 MB
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Ethnopharmacology is a multidisciplinary subject and an area of research where tradition and modern science coexists. The progress of this interdisciplinary science is expanding fast with our increasing quest for phytopharmaceuticals and our increasing awareness on traditional and alternative systems of medicines. The book is a compilation of articles written by eminent researchers working on phytomedicine and on various aspects of ethnopharmacology. Many of the articles are modern approaches to ethnopharmacological research. The book will be immensely useful to students, teachers, scientists and pharmaceutical industries interested in plant based medicine and drug development. Contents Chapter 1: Mechanisms of Apoptosis Induced by Garlic-Derived Components by D Karunagaran and Suby Oommen; Chapter 2: Music Therapy: An Introduction by T V Sairam; Chapter 3: Application of Traditional Knowledge of Medicinal Plants by Tribes of Some Part of Rajasthan; Chapter 4: An Experimental Evaluation to the Anticancer Activity of Homeopathic Medicines by Ramadasan Kuttan, Girija Kuttan, E S Sunila, K C Preethi, C Nimita Venugopal and K B Hari Kumar; Chapter 5: Molecular Mechanisms Underlying Immunomodulatory Effects of Viscum album Preparations by Fabienne Prost, Jean-Paul Duong Van Huyen, Sriramulu Elluru, Sandrime Delignat, Jagadeesh Bayry, Michel D Kazatchkine and Srini V Kaveri; Chapter 6: A Rasayana, ICHOR-CR as a Possible Chemoprotectant Againt Doxorubicin-Related Toxicity by Renee Vanessa Gardner, Hernan Correa, Randall Craver, Evangeline Mckinnon, Halina Sadowska-Krowicka and Rajasekharan Warrier; Chapter 7: Ethnomedicinal Potential of Herbal Drugs on Gastric Dysfunction in Experimental Animals by Ch V Rao and P Pushpangadam; Chapter 8: Anti-inflammatory, Anti-inflammatory, Antinociceptive and Diuretic Activities of Amoora cucullata Roxb by A K Das, I Z Shahid, M S K Choudhuri, J A Shilpi and Firoj Ahmed; Chapter 9: The Role of Ethnomedical Leads in Drug Discovery by V George and J Anil John; Chapter 10: Quality of Natural Health Products through Marker Profiling: Promotion and International Coordination by Pulok K Mukherjee, V Kumar, Peter J Houghton; Chapter 11: Potential Use of Some Natural Compounds as Radioprotectors C K K Nair; Chapter 12: Resveratrol Miracle: From Chemoprevention to Cardioprotection by Samarjit Das and Dipak K Das; Chapter 13: Protective Effect of Phytochemicals in Cancer Chemoprevention, Wound Healing and Ischemia-Reperfusion Injury by Rajesh L Thangapazham, Anuj Sharma, and Radha K Maheshwari; Chapter 14: A Brief Review on Phytoconstituents with Potential Antidiabetic Activity by K Rajendran and Annie Shirwaikar; Chapter 15: Scientific Evaluation of Traditional Medicine: Ethnopharmacology, Reverse Pharmacology, System Biology to Metabolmics by Palpu Pushpangadan, R Govindarajan, S K Srivastava, Ch V Rao, K Narayanan Nair, A K S Rawat, Shanta Mehrotra, A K Sharma, S Rajasekharan, V George and P G Latha; Chapter 16: Biological Diversity in Curcuma: A Review by Sharad Srivastava, A K S Rawat and Shanta Mehrotra; Chapter 17: Therapeutic Potential of Medicinal Mushrooms Occurring in South India Amelioration of Oxidative Stress-Induced Hepato-Renal Damages: A Pre-Clinical Evaluation by T A Ajith and K K Janardhanan; Chapter 18: Traditional Medicine and the Intellectual Property Rights (IPR) Regime of 21st Century by Palpu Pushpangadam; Chapter 19: Antimitotic Polysaccharide from Punica granatum by T T Sreelekha, K K Vijayan, Prabha Balaram; Chapter 20: Documentation of Traditional Knowledge and IPR Protection Related to Plants Used for Food and Medicine by S Rajasekharan, P G Latha and P Pushpangadan
Category: Ethnopharmacology