This unique reference source, edited by the world's most respected expert on molecular interaction field software, covers all relevant principles of the GRID force field and its applications in medicinal chemistry. Entire chapters on 3D-QSAR, pharmacophore searches, docking studies, metabolism predictions and protein selectivity studies, among others, offer a concise overview of this emerging field. As an added bonus, this handbook includes a CD-ROM with the latest commercial versions of the GRID program and related software.
Both volumes of this dictionary consists of some 63,000 and over 100,000 translations from all the main areas of chemistry and chemical technology including: Analytical Chemistry, Biochemistry, Biotechnology, Chromatography, Colour, Inorganic Chemistry, Laboratory techniques, Metallurgy & Treatment, Organic chemistry, Physical chemistry, Plastics, Process engineering, Spectroscopy and Industrial Chemistry.
Providing a comprehensive introduction to environmental chemistry, this volume presents an excellent overview of the important chemical aspects of pollution occurring in the atmosphere, in water and in soil. Presented in the book are: * commonly known harmful substances, such as carbon monoxide, heavy metals, and sulfur dioxide * toxins in food and basic consumer goods * radioisotopes such as plutonium and uranium It contains many examples and solutions to practical environmental problems such as pollution via foodstuffs, pesticides and detergents, showing their relation to biochemical processes, toxicology, climate, ecological aspects and other adjacent sciences. The range of topics covered in this book ensures it will be indispensable not only to students of chemistry but also for all those interested in the chemical principles of environmental pollutants.
Author : Mahendra Sahai
ISBN : 3709101409
Genre : Science
File Size : 66.60 MB
Format : PDF
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Lignans, by convention, are a group of natural products that are formed by linking two phenylpropanoid units (C C units) by oxidative coupling. Most importantly, in 6 3 a lignan, two (C C units) are bound through the central carbon of their side chains, 6 3 0 i. e. the 8 and 8 positions (1, 2). The occurrence of C C -dimers, linked at sites other 6 3 0 than the 8–8 positions, is also known and these compounds have been termed neolignans (3, 4). As these two groups of compounds have close structural as well as biosynthetic relationships, they are often associated together and incorporated under the general term “lignan” (5). The diverse structural categorization of true lignans and of a few neolignans is presented in Fig. 1. Through the years, several review articles or books covering different facets of lignans, including their ch- istry (6, 7), biogenesis (8), synthesis (9), and biological activities (10) have been published. Enduring research for the investigation of secondary metabolites of plants has evidenced some compounds that are biogenetically related to true lignans or neolignans but bear some features not discerned in conventional lignans. These compounds or groups of compounds have been termed as “non-conventional lignans”, and include coumarinolignans, ?avonolignans, and stilbenolignans. The non-conventional lignans, like the conventional ones, have two C C units linked 6 3 together but have additional structural features to place them also under the category of coumarins, ?avonoids, or stilbenes.