CAVE MICROBIOMES A NOVEL RESOURCE FOR DRUG DISCOVERY 1 SPRINGERBRIEFS IN MICROBIOLOGY

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Cave Microbiomes A Novel Resource For Drug Discovery

Author : Naowarat Cheeptham
ISBN : 9781461452065
Genre : Medical
File Size : 24.59 MB
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This book details recent findings in the field of cave microbiology and builds on fast-paced efforts to exploit an unconventional and underexplored environment for new microorganisms which may provide an untapped source of drugs: microorganisms from caves.
Category: Medical

Microbial Life Of Cave Systems

Author : Annette Summers Engel
ISBN : 9783110339888
Genre : Nature
File Size : 78.30 MB
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The earth's subsurface contains abundant and active microbial biomass, living in water, occupying pore space, and colonizing mineral and rock surfaces. Caves are one type of subsurface habitat, being natural, solutionally- or collapse-enlarged openings in rock. Within the past 30 years, there has been an increase in the number of microbiology studies from cave environments to understand cave ecology, cave geology, and even the origins of life. By emphasizing the microbial life of caves, and the ecological processes and geological consequences attributed to microbes, this book provides the first authoritative and comprehensive account of the microbial life of caves for students, professionals, and general readers.
Category: Nature

Bioresources And Bioprocess In Biotechnology

Author : Shiburaj Sugathan
ISBN : 9789811042843
Genre : Science
File Size : 79.27 MB
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This book is a compilation of detailed articles on various products and services that can be derived from bioresources through bioprocess. It offers in-depth discussions and case studies on commercially and therapeutically important enzymes, antimicrobials, anti-cancer molecules and anti-inflammatory substances. It also includes a separate section on emerging trends in bioactive substances research. This unique book is a valuable source of information for biotechnologists and bioprocess experts as well as academics and researchers who are actively involved in product and process development.
Category: Science

Water Civilization

Author : Yoshinori Yasuda
ISBN : 9784431541103
Genre : Social Science
File Size : 72.90 MB
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Water Civilization: From Yangtze to Khmer Civilizations comprises three major topics: 1) Discovery of the origin of rice agriculture and the Yangtze River civilization in southern China was mainly based on investigation of the Chengtoushan archaeological site, the earliest urban settlement in East Asia. The origin of rice cultivation can be traced back to 10000 BC, with urban settlement starting at about 6000 BP; 2) The Yangtze River civilization collapsed around 4200 BP. Palaeoenvironmental studies including analyses of annually laminated sediments in East and Southeast Asia indicate a close relationship between climate change and the rise and fall of the rice-cultivating and fishing civilization; and 3) Migrations from southern China to Southeast Asia occurred after about 4200 BP. Archaeological investigation of the Phum Snay site in Cambodia, including analyses of DNA and human skeletal remains, reveals a close relationship to southern China, indicating the migration of people from southern China to Southeast Asia. This publication is an important contribution to understanding the environmental history of China and Cambodia in relation to the rise and fall of the rice-cultivating and fishing civilization, which we call water civilization.
Category: Social Science

Microbial Cell Factories

Author : Deepansh Sharma
ISBN : 9781351668040
Genre : Medical
File Size : 59.39 MB
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Microbial Cell Factories is a conceptual, reference-based source including chapters covering microbial cell factories for industrial developments, microbial biotechnology for sustainable environmental solutions and agriculture practices, uses of microorganisms in food processing, metabolites as next generation food additives/food processing, and microbial cell factories in alternative energy fuel generation. The book highlights trends and developments in the field of microbial products, written by by an international team of leading academic and research scholars.
Category: Medical

Aging Research Methodological Issues

Author : Carmen García-Peña
ISBN : 9783319183237
Genre : Medical
File Size : 41.90 MB
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This book reviews classical epidemiological and clinical research studies, with a focus on aging. Chapters cover methodological topics like the scientific method, ethics, and the consequences of certain exclusion criteria and the work includes a look at clinical concepts like multi morbidity, frailty and functionality. The authors reveal the issues and challenges for researchers of age and aging, and also consider the translation of scientific knowledge, from basic to clinical and from clinical to public policies of social and health care. The focus on aging is what gives this book its valuable perspective on research methodology. All authors have considerable experience in aging, geriatrics or gerontology and each chapter includes both a theoretical framework and practical examples of studies in aging. Readers will discover study designs that are reviewed for basic structure, main flaws and advantages and are analyzed for specific conditions and variables regarding aging. This text is suited to both health care professionals caring for older adults and researchers who are new to research in aging. It is relevant across the disciplines, including medicine, psychology, social sciences and dentistry and it supports learning with graphs and figures.
Category: Medical

Bio Pigmentation And Biotechnological Implementations

Author : Om V. Singh
ISBN : 9781119166184
Genre : Science
File Size : 42.49 MB
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Recent technological advances have provided unique opportunities for the exploration of alternatives to the industrial use of chemically produced synthetic colors. The most promising developments in this area have been in bio-pigmentation derived from microorganisms. This groundbreaking book reviews the current state of the science of bio-pigmentation, providing important insights into the molecular mechanisms of microbial biosynthesis of industrial pigments. Featuring contributions by leading researchers from both industry and academe, it explores the latest advances in the use of bio-pigments as safe, sustainable alternatives to chemically synthesized pigments, and provides extensive coverage the most promising sources of bio-pigments within the food, feed, and pharmaceutical industries. • Proposes microbial uniqueness of coloration in variety of food, feed and pharmaceuticals • Covers the basic science behind bio-pigmentation as well as the latest advances in the field • Describes detection strategies for screening and identifying color producing microorganisms under varying environmental conditions • Provides an exhaustive review of the literature on color producing extremophiles and offers fascinating insights into color production as a stress response in extremophiles • Explores microbial molecular mechanisms of color production, with special coverage of color production as secondary metabolites under environmental stress Bio-pigmentation and Biotechnological Implementations is required reading for professionals and post-doctoral students of microbiology, applied microbiology, food microbiology, food science, and food biochemistry. It is a valuable working resource for scientists working in color-dependent food, feed, and pharmaceuticals.
Category: Science

Antibiotics

Author : Sergio Sanchez
ISBN : 9781908230553
Genre : Medical
File Size : 79.90 MB
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The 'golden age' for antibiotic discovery, from 1940 until the early 1970s, ushered in a new era in human- and animal-health and the associated dramatic increase in human life expectancies. Indeed the possibility of eradicating infectious disease seemed feasible. However it soon became apparent that microorganisms wouldn't be defeated so easily. Their weapon: antibiotic resistance. Today microbial antibiotic resistance is rapidly exhausting our supply of effective compounds and making the possibility of a global public health disaster seems likely. The urgency of this situation has spawned a plethora of new multi-disciplinary research initiatives looking for novel antibiotics and other antimicrobial agents. In this timely book respected international experts summarize the most important research to provide a timely overview of the field. Opening chapters define 'antibiotic', explain why we need new compounds, outline the applications of antibiotics, both old and new, and describe the producing microbes. These are followed by chapters that cover antibiotic resistance, toxicity, overuse, new antimicrobial sources, new targets, novel technologies for antibiotic discovery (e.g. silent gene clusters), lantibiotics, natural antivirals, new macrolide derivatives, and antibiotics in the pipeline. This book is essential reading for everyone working in antimicrobial research in academia, biotechnology companies, and the pharmaceutical industry and a recommended volume for all microbiology libraries.
Category: Medical

Towards An Interdisciplinary Approach In Earth System Science

Author : Gerrit Lohmann
ISBN : 9783319138657
Genre : Science
File Size : 80.59 MB
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This book describes the latest advances at the Helmholtz “Earth System Science Research School” where scientists from the Alfred Wegener Institute in Bremerhaven, the University of Bremen, and the Jacobs University are involved in research. One of the greatest challenges is understanding ongoing environmental changes. The longer the time scale the more components of the Earth system are involved, e.g. interannual and decadal variations are related to the coupled atmosphere-ocean-sea ice system, whereas longer variations like glacial-interglacial or Cenozoic transitions involve the carbon cycle, ice sheets and gateways. In order to get deep insights into Earth system science, observations, remote sensing, past environmental data, as well as modeling need to be integrated. These different approaches are traditionally taught in separated disciplines at bachelor and master levels. It is, therefore, necessary to bring these disciplines together in PhD programs.
Category: Science

Free Radicals And Diseases

Author : Tilman Grune
ISBN : 9781586035181
Genre : Medical
File Size : 47.49 MB
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This publication contains an extensive overview of free radicals and diseases, including both basic science approaches and clinical applications. The research of the last decades has contributed substantially to the understanding role and function of these metabolites. It is the aim of the editors to include a large variety of biological models ranging from yeast over mitochondria, isolated cells and cell culture models to animals and humans. The topics discussed focus on the function and integrity of mitochondria under oxidative conditions, the role of protein oxidation and proteolysis in the cellular stress response. Also the new aspects in the fields of antioxidant treatment are dealt with intensively. Some chapters are introducing more methodological approaches and their application in the investigation of oxidative stress and diseases related to this condition.
Category: Medical