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Cardiovascular Genomics New Pathophysiological Concepts

Author : P.A.F.M. Doevendans
ISBN : 9781461510055
Genre : Medical
File Size : 66.94 MB
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Four years ago-in December 1997-the first European Science Foundation Workshop on Cardiovascular Specific Gene Expression was held in Maastricht. It was hardly possible to imagine the progress in the field in those four years. In 1997, gene expression was still an art focused on individual genes; in 200 I, many labs have access to micro-array facilities to determine the expression of thousands of genes simultaneously. In 1997, gene expression was an area of fundamental research in basis molecular biology laboratories; in 200 I, clinical cardiovascular research has incorporated gene expression approaches. In 1997, the interpretation of a gene expression experiment was usually straightforward; in 200 I, advanced bioinformatics tools are needed to approach the extreme complexities of genetic control of cell and tissue function. The second symposium in this series is focused on Cardiovascular Genomics. New Pathophysiological Concepts. The organizing committee chose to invite a group of renown scientists and young investigators around four topics of eminent importance in cardiovascular research. These topics reflect the major present-day clinical cardiovascular problems: atherosclerosis, hypertension, arrhythmias and heart failure. In addition to these four disease-driven topics, the workshop has sessions on gene expression methodologies and cellular transplant approaches to cardiovascular disease.
Category: Medical

Books In Print

Author :
ISBN : UOM:39015062097749
Genre : American literature
File Size : 33.88 MB
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Books in print is the major source of information on books currently published and in print in the United States. The database provides the record of forthcoming books, books in-print, and books out-of-print.
Category: American literature

Forthcoming Books

Author : R.R. Bowker Company. Department of Bibliography
ISBN : 00158119
Genre :
File Size : 89.2 MB
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Atrial Fibrillation Therapy

Author : Gheorghe-Andrei Dan
ISBN : 9781447154754
Genre : Medical
File Size : 20.53 MB
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The paradigm for atrial fibrillation (AF) management has changed significantly in recent years. A new era has begun for the prevention of one of the most tremendous complication of AF, stroke. Prevention of ischemic stroke in AF patients with oral anticoagulants represents a huge challenge because of the narrow therapeutic change of these drugs, interindividual and intraindividual variability, and the unsatisfactory time in therapeutically range (TTR) with this type of medication. New guidelines have emerged as a result of new mechanisms for initiation and perpetuation for pharmacotherapy to cure AF and trials with new classes of antithrombotic drugs are ongoing. The treatment of AF is still in its infancy, but recent research is revealing how it can be applied with optimal efficacy. This book assists trainees, recertifying physicians, practicing physicians and other professional staff in internal medicine, cardiology, emergency medicine, and clinical pharmacology to apply new diagnostic tools for selecting the best treatment options for AF patients.
Category: Medical

Cardiovascular Genetics For Clinicians

Author : P.A.F.M. Doevendans
ISBN : 9789401010191
Genre : Medical
File Size : 44.18 MB
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All physicians practicing medicine encounter patients suffering from cardiovascular disease. This book has been outlined in such a way that vascular surgeons, general internists, neurologists and cardiologists should be able to use it. The book covers the complete scope of cardiac diseases in addition to chapters on hypertension and atherosclerosis. In many patients there is a family history of cerebrovascular accidents, myocardial infarction or peripheral arterial disease. Also in patients reporting collaps, palpitations and arrhythmias the family is crucial and can provide clues to a genetic cause of the disease. This book is published to guide physicians in the process of determining whether a genetic component is likely to be present. Furthermore, information is provided what the possibilities and limitations of DNA diagnostic techniques are. Finally, the importance of newly identified categories of potential patients, i. e. gene carriers without symptoms or any inducible sign of disease, is highlighted. For some patients a genetic diagnosis is essential to determine appropriate therapy and for counseling? In some other diseases DNA diagnostic tools are available but the relevant for the patients may be less clear. In other families the search for a disease causing gene is ongoing and the possibilities to find genes and to unravel the pathophysiology of the disease is limited by the lack of patients. To give insight into the current state of genetic diagnostics, the authors have classified the cardiovascular diseases.
Category: Medical

Cardiac Arrest

Author : Norman A. Paradis
ISBN : 9781139465700
Genre : Medical
File Size : 79.54 MB
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Cardiac Arrest is the definitive and most comprehensive reference in advanced life support and resuscitation medicine. This new edition brings the reader completely up-to-date with developments in the field, focusing on practical issues of decision making, clinical management and prevention, as well as providing clear explanations of the science informing the practice. The coverage includes information on the latest pharmacotherapeutic options, the latest chest compression techniques and airway management protocols, all backed by clearly explained, evidence-based scientific research. The content is consistent with the latest guidelines for practice in this area, as detailed by the major international governing organisations. This volume is essential reading for all those working in the hospital environments of emergency medicine, critical care, cardiology and anesthesia, as well as those providing care in the pre-hospital setting, including paramedics and other staff from the emergency services.
Category: Medical

Understanding Clinical Cardiac Electrophysiology

Author : Peter Spector
ISBN : 9781118905463
Genre : Medical
File Size : 23.14 MB
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In the fast paced world of clinical training, students are often inundated with the what of electrophysiology without the why. This new text is designed to tell the story of electrophysiology so that the seemingly disparate myriad observations of clinical practice come into focus as a cohesive and predictable whole. Presents a unique, conceptually-guided approach to understanding the movement of electrical current through the heart, the impact of various disease states and the positive effect of treatment Reviews electrophysiologic principles and the analytic tools which, when combined with a firm grasp of EP mechanisms, allow the reader to think through any situation Presents the mathematics necessary for the practice of cardiac electrophysiology in an accessible and understandable manner Contains accompanying video clips, including computer simulations showing the flow of electrical current through the heart, which help explain and visualise concepts discussed in the text Includes helpful chapter summaries and full color illustrations aid comprehension
Category: Medical

Head And Neck Vascular Anomalies

Author : Gresham T. Richter
ISBN : 9781597567343
Genre : Medical
File Size : 34.37 MB
Format : PDF
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Head and Neck Vascular Anomalies: A Practical Case-Based Approach is a useful guide to the management of lesions caused by vascular anomalies, providing specific treatment algorithms for their management. This book offers consistent and straightforward techniques to the more frequently encountered and some of the more difficult vascular anomalies. Coming from the world-renowned vascular anomalies center at the University of Arkansas for Medical Sciences, known for its clinical expertise and multi-disciplinary approach, editors Dr. Suen and Dr. Richter have over 40 years combined experience in treating these lesions. With contributed chapters from international leaders in the field, the editors present a practical guide, based upon clinical and scientific evidence, on the approach to diagnosis and management to each vascular anomaly based upon type, extent and location. The book provides a case-based approach to simple and complex lesions. Initial steps for diagnosis followed by a recommended treatment approach is presented with photographs, imaging and step-by-step illustrations to surgical or alternative therapies. All presented information is based upon current literature, providing a timeless and seamless algorithm to each lesion. Each case begins with a diagnostic approach, followed by next best steps to imaging treatment and follow up. This case-based approach is a wonderful quick resource for those physicians in a variety of specialties making clinical decisions. With the increasing number of vascular anomaly centers, and physicians participating in the care of these patients along with the recent advancements and consistency in managing these patients, the timing for this text is ideal.
Category: Medical

Progress In Catheter Ablation

Author : Liong Bing Liem
ISBN : 9789401597913
Genre : Medical
File Size : 45.75 MB
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Catheter ablation is widely accepted as an effective and safe form of therapy for cardiac arrhythmia. In many instances this curative procedure is considered as the first line of therapy if not the ultimate treatment of choice. With the use of radiofrequency (RF) modality; which has revolutionized the technology from a barotraumatic, potentially injurious procedure using high voltage, direct-current (DC) shock to a safe and relatively painless one; catheter ablation procedure now carries a very low risk and is extremely effective for certain types of arrhythmia. Its efficacy rate in curing supraventricular tachycardia involving an accessory pathway or dual atrioventricular nodal pathways has been near perfect and its application for certain types of atrial and ventricular arrhythmia have also been very satisfactory. However, conventional RF ablation has several well known limitations, most notably is its ability to only produce relatively small, point lesions; rendering it effective only for an arrhythmia with a small and/or a superficial target. It was soon recognized that the technology would not likely to have significant utility in arrhythmia with a more widespread target such as atrial fibrillation or those which involve scarred and deep myocardial tissue such as ventricular tachycardia. Indeed, the application of conventional RF technology in these complex but common arrhythmia has yielded unsatisfactory results.
Category: Medical