BIOINFORMATICS THE MACHINE LEARNING APPROACH ADAPTIVE COMPUTATION AND MACHINE LEARNING SERIES

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Bioinformatics

Author : Pierre Baldi
ISBN : 026202506X
Genre : Computers
File Size : 86.29 MB
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A guide to machine learning approaches and their application to the analysis of biological data.
Category: Computers

Deep Learning

Author : Ian Goodfellow
ISBN : 9780262035613
Genre : Computers
File Size : 76.95 MB
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An introduction to a broad range of topics in deep learning, covering mathematical and conceptual background, deep learning techniques used in industry, and research perspectives.
Category: Computers

Introduction To Machine Learning

Author : Ethem Alpaydin
ISBN : 9780262028189
Genre : Computers
File Size : 85.58 MB
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The goal of machine learning is to program computers to use example data or past experience to solve a given problem. Many successful applications of machine learning exist already, including systems that analyze past sales data to predict customer behavior, optimize robot behavior so that a task can be completed using minimum resources, and extract knowledge from bioinformatics data. Introduction to Machine Learning is a comprehensive textbook on the subject, covering a broad array of topics not usually included in introductory machine learning texts. Subjects include supervised learning; Bayesian decision theory; parametric, semi-parametric, and nonparametric methods; multivariate analysis; hidden Markov models; reinforcement learning; kernel machines; graphical models; Bayesian estimation; and statistical testing.Machine learning is rapidly becoming a skill that computer science students must master before graduation. The third edition of Introduction to Machine Learning reflects this shift, with added support for beginners, including selected solutions for exercises and additional example data sets (with code available online). Other substantial changes include discussions of outlier detection; ranking algorithms for perceptrons and support vector machines; matrix decomposition and spectral methods; distance estimation; new kernel algorithms; deep learning in multilayered perceptrons; and the nonparametric approach to Bayesian methods. All learning algorithms are explained so that students can easily move from the equations in the book to a computer program. The book can be used by both advanced undergraduates and graduate students. It will also be of interest to professionals who are concerned with the application of machine learning methods.
Category: Computers

Introduction To Computational Biology

Author : Michael S. Waterman
ISBN : 9781351437080
Genre : Mathematics
File Size : 88.37 MB
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Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems associated with reading DNA sequences and comparing sequences to finding common patterns. The author then considers that statistics of pattern counts in sequences, RNA secondary structure, and the inference of evolutionary history of related sequences. Introduction to Computational Biology exposes the reader to the fascinating structure of biological data and explains how to treat related combinatorial and statistical problems. Written to describe mathematical formulation and development, this book helps set the stage for even more, truly interdisciplinary work in biology.
Category: Mathematics

Learning With Kernels

Author : Bernhard Schölkopf
ISBN : 0262194759
Genre : Computers
File Size : 27.65 MB
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A comprehensive introduction to Support Vector Machines and related kernel methods.
Category: Computers

Machine Learning In Non Stationary Environments

Author : Masashi Sugiyama
ISBN : 9780262300438
Genre : Computers
File Size : 77.19 MB
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As the power of computing has grown over the past few decades, the field of machine learning has advanced rapidly in both theory and practice. Machine learning methods are usually based on the assumption that the data generation mechanism does not change over time. Yet real-world applications of machine learning, including image recognition, natural language processing, speech recognition, robot control, and bioinformatics, often violate this common assumption. Dealing with non-stationarity is one of modern machine learning's greatest challenges. This book focuses on a specific non-stationary environment known as covariate shift, in which the distributions of inputs (queries) change but the conditional distribution of outputs (answers) is unchanged, and presents machine learning theory, algorithms, and applications to overcome this variety of non-stationarity. After reviewing the state-of-the-art research in the field, the authors discuss topics that include learning under covariate shift, model selection, importance estimation, and active learning. They describe such real world applications of covariate shift adaption as brain-computer interface, speaker identification, and age prediction from facial images. With this book, they aim to encourage future research in machine learning, statistics, and engineering that strives to create truly autonomous learning machines able to learn under non-stationarity.
Category: Computers

Feature Engineering For Machine Learning

Author : Alice Zheng
ISBN : 9781491953198
Genre : Computers
File Size : 78.69 MB
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Feature engineering is a crucial step in the machine-learning pipeline, yet this topic is rarely examined on its own. With this practical book, you’ll learn techniques for extracting and transforming features—the numeric representations of raw data—into formats for machine-learning models. Each chapter guides you through a single data problem, such as how to represent text or image data. Together, these examples illustrate the main principles of feature engineering. Rather than simply teach these principles, authors Alice Zheng and Amanda Casari focus on practical application with exercises throughout the book. The closing chapter brings everything together by tackling a real-world, structured dataset with several feature-engineering techniques. Python packages including numpy, Pandas, Scikit-learn, and Matplotlib are used in code examples. You’ll examine: Feature engineering for numeric data: filtering, binning, scaling, log transforms, and power transforms Natural text techniques: bag-of-words, n-grams, and phrase detection Frequency-based filtering and feature scaling for eliminating uninformative features Encoding techniques of categorical variables, including feature hashing and bin-counting Model-based feature engineering with principal component analysis The concept of model stacking, using k-means as a featurization technique Image feature extraction with manual and deep-learning techniques
Category: Computers

Machine Learning In Bioinformatics

Author : Yanqing Zhang
ISBN : 0470397411
Genre : Computers
File Size : 73.77 MB
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An introduction to machine learning methods and their applications to problems in bioinformatics Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. From an internationally recognized panel of prominent researchers in the field, Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics. Coverage includes: feature selection for genomic and proteomic data mining; comparing variable selection methods in gene selection and classification of microarray data; fuzzy gene mining; sequence-based prediction of residue-level properties in proteins; probabilistic methods for long-range features in biosequences; and much more. Machine Learning in Bioinformatics is an indispensable resource for computer scientists, engineers, biologists, mathematicians, researchers, clinicians, physicians, and medical informaticists. It is also a valuable reference text for computer science, engineering, and biology courses at the upper undergraduate and graduate levels.
Category: Computers

Bayesian Reasoning And Machine Learning

Author : David Barber
ISBN : 9780521518147
Genre : Computers
File Size : 75.94 MB
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A practical introduction perfect for final-year undergraduate and graduate students without a solid background in linear algebra and calculus.
Category: Computers

Kernel Methods And Machine Learning

Author : S. Y. Kung
ISBN : 9781139867634
Genre : Computers
File Size : 66.76 MB
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Offering a fundamental basis in kernel-based learning theory, this book covers both statistical and algebraic principles. It provides over 30 major theorems for kernel-based supervised and unsupervised learning models. The first of the theorems establishes a condition, arguably necessary and sufficient, for the kernelization of learning models. In addition, several other theorems are devoted to proving mathematical equivalence between seemingly unrelated models. With over 25 closed-form and iterative algorithms, the book provides a step-by-step guide to algorithmic procedures and analysing which factors to consider in tackling a given problem, enabling readers to improve specifically designed learning algorithms, build models for new applications and develop efficient techniques suitable for green machine learning technologies. Numerous real-world examples and over 200 problems, several of which are Matlab-based simulation exercises, make this an essential resource for graduate students and professionals in computer science, electrical and biomedical engineering. Solutions to problems are provided online for instructors.
Category: Computers