AN INTRODUCTION TO MOLECULAR EVOLUTION AND PHYLOGENETICS

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An Introduction To Molecular Evolution And Phylogenetics

Author : Lindell Bromham
ISBN : 9780198736363
Genre :
File Size : 86.23 MB
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An Introduction to Molecular Evolution and Phylogenetics presents the fundamental concepts and intellectual tools you need to understand how the genome records information about evolutionary past and processes, how that information can be "read", and what kinds of questions we can use that information to answer. Starting with evolutionary principles, and illustrated throughout with biological examples, it is the perfect starting point on the journey to anunderstanding of the way molecular data is used in modern biology.
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Evolution

Author : Brian Charlesworth
ISBN : 3150187052
Genre :
File Size : 49.16 MB
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Evolution auf den Punkt gebracht. Eine kurze Einführung in die Prinzipien und Fragen der Entstehung und Entwicklung des Lebens auf unserem Planeten.
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Molecular Evolution

Author : Roderick D.M. Page
ISBN : 9781444313369
Genre : Science
File Size : 80.43 MB
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The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.
Category: Science

Molecular Evolution And Phylogenetics

Author : Masatoshi Nei
ISBN : 0195135857
Genre : Medical
File Size : 86.81 MB
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During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.
Category: Medical

Statistical Methods In Molecular Evolution

Author : Rasmus Nielsen
ISBN : 9780387277332
Genre : Science
File Size : 23.23 MB
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In the field of molecular evolution, inferences about past evolutionary events are made using molecular data from currently living species. With the availability of genomic data from multiple related species, molecular evolution has become one of the most active and fastest growing fields of study in genomics and bioinformatics. Most studies in molecular evolution rely heavily on statistical procedures based on stochastic process modelling and advanced computational methods including high-dimensional numerical optimization and Markov Chain Monte Carlo. This book provides an overview of the statistical theory and methods used in studies of molecular evolution. It includes an introductory section suitable for readers that are new to the field, a section discussing practical methods for data analysis, and more specialized sections discussing specific models and addressing statistical issues relating to estimation and model choice. The chapters are written by the leaders of field and they will take the reader from basic introductory material to the state-of-the-art statistical methods. This book is suitable for statisticians seeking to learn more about applications in molecular evolution and molecular evolutionary biologists with an interest in learning more about the theory behind the statistical methods applied in the field. The chapters of the book assume no advanced mathematical skills beyond basic calculus, although familiarity with basic probability theory will help the reader. Most relevant statistical concepts are introduced in the book in the context of their application in molecular evolution, and the book should be accessible for most biology graduate students with an interest in quantitative methods and theory. Rasmus Nielsen received his Ph.D. form the University of California at Berkeley in 1998 and after a postdoc at Harvard University, he assumed a faculty position in Statistical Genomics at Cornell University. He is currently an Ole Rømer Fellow at the University of Copenhagen and holds a Sloan Research Fellowship. His is an associate editor of the Journal of Molecular Evolution and has published more than fifty original papers in peer-reviewed journals on the topic of this book. From the reviews: "...Overall this is a very useful book in an area of increasing importance." Journal of the Royal Statistical Society "I find Statistical Methods in Molecular Evolution very interesting and useful. It delves into problems that were considered very difficult just several years ago...the book is likely to stimulate the interest of statisticians that are unaware of this exciting field of applications. It is my hope that it will also help the 'wet lab' molecular evolutionist to better understand mathematical and statistical methods." Marek Kimmel for the Journal of the American Statistical Association, September 2006 "Who should read this book? We suggest that anyone who deals with molecular data (who does not?) and anyone who asks evolutionary questions (who should not?) ought to consult the relevant chapters in this book." Dan Graur and Dror Berel for Biometrics, September 2006 "Coalescence theory facilitates the merger of population genetics theory with phylogenetic approaches, but still, there are mostly two camps: phylogeneticists and population geneticists. Only a few people are moving freely between them. Rasmus Nielsen is certainly one of these researchers, and his work so far has merged many population genetic and phylogenetic aspects of biological research under the umbrella of molecular evolution. Although Nielsen did not contribute a chapter to his book, his work permeates all its chapters. This book gives an overview of his interests and current achievements in molecular evolution. In short, this book should be on your bookshelf." Peter Beerli for Evolution, 60(2), 2006
Category: Science

Algorithmen Und Datenstrukturen

Author : Thomas Ottmann
ISBN : 9783662556504
Genre : Computers
File Size : 87.90 MB
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Dieses bestens eingeführte Lehrbuch wendet sich an Studierende der Informatik in Grund- und Hauptstudium. Es behandelt gut verständlich alle Themen, die üblicherweise in der Standardvorlesung "Algorithmen und Datenstrukturen” vermittelt werden. Die einzelnen Algorithmen werden theoretisch fundiert dargestellt; ihre Funktionsweise wird ausführlich anhand vieler Beispiele erläutert. Zusätzlich zur halbformalen Beschreibung werden wichtige Algorithmen in Java formuliert. Das Themenspektrum reicht von Algorithmen zum Suchen und Sortieren über Hashverfahren, Bäume, Manipulation von Mengen bis hin zu Geometrischen Algorithmen und Graphenalgorithmen. Dabei werden sowohl der Entwurf effizienter Algorithmen und Datenstrukturen als auch die Analyse ihres Verhaltens mittels mathematischer Methoden behandelt. Durch eine übersichtliche Gliederung, viele Abbildungen und eine präzise Sprache gelingt den Autoren in vorbildlicher Weise die Vermittlung des vielschichtigen Themengebiets. Die 5. Auflage ist vollständig durchgesehen und überarbeitet. Neu aufgenommen wurden Einführungen in die Themen Dynamisches Programmieren, Backtracking, Onlinealgorithmen, Approximationsalgorithmen sowie einige Algorithmen für spezielle Probleme wie die schnelle Multiplikation von Matrizen, von ganzen Zahlen, und die Konstruktion der konvexen Hülle von Punkten in der Ebene. Das Buch eignet sich zur Vorlesungsbegleitung, zum Selbststudium und zum Nachschlagen. Eine Vielzahl von Aufgaben dient der weiteren Vertiefung des Gelernten. Unter http://ad.informatik.uni-freiburg.de/bibliothek/books/ad-buch/ werden Java-Programme für die wichtigsten Algorithmen und ergänzende Materialien zum Buch bereitgestellt.
Category: Computers

Analysis Of Phylogenetics And Evolution With R

Author : Emmanuel Paradis
ISBN : 9781461417439
Genre : Science
File Size : 81.10 MB
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The increasing availability of molecular and genetic databases coupled with the growing power of computers gives biologists opportunities to address new issues, such as the patterns of molecular evolution, and re-assess old ones, such as the role of adaptation in species diversification. In the second edition, the book continues to integrate a wide variety of data analysis methods into a single and flexible interface: the R language. This open source language is available for a wide range of computer systems and has been adopted as a computational environment by many authors of statistical software. Adopting R as a main tool for phylogenetic analyses will ease the workflow in biologists' data analyses, ensure greater scientific repeatability, and enhance the exchange of ideas and methodological developments. The second edition is completed updated, covering the full gamut of R packages for this area that have been introduced to the market since its previous publication five years ago. There is also a new chapter on the simulation of evolutionary data. Graduate students and researchers in evolutionary biology can use this book as a reference for data analyses, whereas researchers in bioinformatics interested in evolutionary analyses will learn how to implement these methods in R. The book starts with a presentation of different R packages and gives a short introduction to R for phylogeneticists unfamiliar with this language. The basic phylogenetic topics are covered: manipulation of phylogenetic data, phylogeny estimation, tree drawing, phylogenetic comparative methods, and estimation of ancestral characters. The chapter on tree drawing uses R's powerful graphical environment. A section deals with the analysis of diversification with phylogenies, one of the author's favorite research topics. The last chapter is devoted to the development of phylogenetic methods with R and interfaces with other languages (C and C++). Some exercises conclude these chapters.
Category: Science

Gene Und Genome

Author : Maxine Singer
ISBN : 3860250019
Genre :
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Molecular Evolution And Adaptive Radiation

Author : Thomas J. Givnish
ISBN : 0521779294
Genre : Science
File Size : 28.14 MB
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This volume surveys advances in the study of adaptive radiation showing how molecular characters can be used to analyze the origin and pattern of diversification within a lineage in a non-circular fashion.
Category: Science

Plant Molecular Evolution

Author : J.J. Doyle
ISBN : 0792360966
Genre : Medical
File Size : 88.85 MB
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Plant molecular biology has produced an ever-increasing flood of data about genes and genomes. Evolutionary biology and systematics provides the context for synthesizing this information. This book brings together contributions from evolutionary biologists, systematists, developmental geneticists, biochemists, and others working on diverse aspects of plant biology whose work touches to varying degrees on plant molecular evolution. The book is organized in three parts, the first of which introduces broad topics in evolutionary biology and summarizes advances in plant molecular phylogenetics, with emphasis on model plant systems. The second segment presents a series of case studies of gene family evolution, while the third gives overviews of the evolution of important plant processes such as disease resistance, nodulation, hybridization, transposable elements and genome evolution, and polyploidy.
Category: Medical